thiosemicarbazide
- CAS No.
- 79-19-6
- Chemical Name:
- thiosemicarbazide
- Synonyms
- HYDRAZINECARBOTHIOAMIDE;TSC;Aminothiourea;n-aminothiourea;TSZ;3-thiosemicarbazide;CHP3;NSC 2213;ai3-16319;NSC 31792
- CBNumber:
- CB0132714
- Molecular Formula:
- CH5N3S
- Molecular Weight:
- 91.14
- MOL File:
- 79-19-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/24 13:33:21
| Melting point | 180-183 °C (dec.)(lit.) |
|---|---|
| Boiling point | 208.6±23.0 °C(Predicted) |
| Density | 1.221 (estimate) |
| vapor pressure | 1.15Pa at 25℃ |
| refractive index | 1.5800 (estimate) |
| storage temp. | Store at +15°C to +25°C. |
| solubility | DMSO : 125 mg/mL (1371.52 mM; Need ultrasonic) |
| pka | pK1:1.5(+1) (25°C,μ=0.1) |
| form | Powder |
| color | White to light yellow |
| PH | 5-7 (50g/l, H2O, 20℃) |
| Water Solubility | soluble |
| Merck | 14,9361 |
| BRN | 506320 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | BRWIZMBXBAOCCF-UHFFFAOYSA-N |
| LogP | -1.67 |
| CAS DataBase Reference | 79-19-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Hydrazinecarbothioamide(79-19-6) |
| EPA Substance Registry System | Thiosemicarbazide (79-19-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300-H412 | |||||||||
| Precautionary statements | P264-P270-P273-P301+P310-P405-P501 | |||||||||
| Hazard Codes | T+ | |||||||||
| Risk Statements | 28-52/53-26/27/28 | |||||||||
| Safety Statements | 22-26-36/37-45-61-28A-36/37/39 | |||||||||
| RIDADR | UN 2811 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VT4200000 | |||||||||
| F | 8-9-23 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29309070 | |||||||||
| HS Code | 29335995 | |||||||||
| Toxicity | LD50 orally in adult Norway rats: 13 mg/kg, Dieke, Proc. Soc. Exp. Biol. Med. 70, 688 (1949) | |||||||||
| NFPA 704 |
|
thiosemicarbazide price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T33405 | Thiosemicarbazide 99% | 79-19-6 | 100G | ₹3420.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T33405 | Thiosemicarbazide 99% | 79-19-6 | 500G | ₹5986.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 89050 | Thiosemicarbazide puriss. p.a., 98% | 79-19-6 | 25G | ₹3637.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 89050 | Thiosemicarbazide puriss. p.a., 98% | 79-19-6 | 100G | ₹10013.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21119 | Thiosemicarbazide for synthesis | 79-19-6 | 250G | ₹8739.99 | 2022-06-14 | Buy |
thiosemicarbazide Chemical Properties,Uses,Production
Chemical Properties
Thiosemicarbazide is an odorless, white crystalline powder.
Uses
Used in TLC to stain alpha-keto acidsThiosemicarbazide is used as a reagent for ketones as well as chemical intermediate. It is involved in the detection of metals. It is also used in photography. Further, it is effective for controlling bacterial leaf blight in rice. In addition to this, it is used to prepare 1,3,4-thiadiazoles.
General Description
N-Aminothiourea is a white crystalline powder and is odorless. N-Aminothiourea is used as a reagent for ketones and certain metals, for photography and as a rodenticide. N-Aminothiourea is also effective for control of bacterial leaf blight of rice. Not a registered pesticide in the U.S. N-Aminothiourea is a chemical intermediate for herbicides and a reagent for detection of metals.
Reactivity Profile
Isocyanates and thioisocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].
Health Hazard
N-Aminothiourea is highly toxic by ingestion. May induce goiter and cause delayed toxic effects in blood and skin. May be mutagenic in human cells.
Fire Hazard
When heated to decomposition, very toxic fumes of sulfur oxides and nitrogen oxides are emitted.
Safety Profile
Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Potential Exposure
Thiosemicarbazide is a dithiocarbamide compound is used as an intermedialte for pharmaceuticals and herbicides; as a reagent for ketones and certain metals; in certain photography and dye operations; as a rodenticide. It is also effective for control of bacterial leaf blight of rice.
Shipping
UN2771 Thiosemicarbazide, pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Purification Methods
Crystallise thiosemicarbazide from H2O (solubility is 20.3% w/w at 80o). The hydrochloride has m 190-191o(dec, 184o also reported). It forms salts with heavy metals. [Beilstein 3 H 195, 3 I 79, 3 II 134, 3 III 315, 3 IV 374.]
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.) and strong reducing agents; contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. May react with nitrates.
thiosemicarbazide Preparation Products And Raw materials
Raw materials
Preparation Products
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Evans Fine Chem | +91-9821340302 +91-9821340302 | Maharashtra, India | 286 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| SHUBH LIFECARE | +91-9328040211 +91-9909086363 | Gujarat, India | 24 | 58 | Inquiry |
| Dhara Industries | +91-9322395199 +91-9322395199 | Mumbai, India | 190 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Valens Molecules | +91-040-23417926 +91-4023417926 | Hyderabad, India | 10 | 58 | Inquiry |
| Medinex Laboratories Pvt Ltd | +91-2782883162 +91-2782883161 | Maharashtra, India | 20 | 58 | Inquiry |
| Bhushilpa Chemicals Pvt Ltd | +91-7498719961 +91-9960027412 | Maharashtra, India | 8 | 58 | Inquiry |
| Orex Pharma Pvt Ltd | +91-9773669524 +91-9167688585 | Maharashtra, India | 11 | 58 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
| Supplier | Advantage |
|---|---|
| Evans Fine Chem | 58 |
| JSK Chemicals | 58 |
| SHUBH LIFECARE | 58 |
| Dhara Industries | 58 |
| Ralington Pharma | 58 |
| Valens Molecules | 58 |
| Medinex Laboratories Pvt Ltd | 58 |
| Bhushilpa Chemicals Pvt Ltd | 58 |
| Orex Pharma Pvt Ltd | 58 |
| ALPHA CHEMIKA | 43 |
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