ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Mercaptopyrimidine >2-Thiobarbituric acid
2-Thiobarbituric acid
- CAS No.
- 504-17-6
- Chemical Name:
- 2-Thiobarbituric acid
- Synonyms
- TBA;THIOBARBITURIC ACID;2-Thioxodihydropyrimidine-4,6(1H,5H)-dione;2-sulfanylpyriMidine-4,6-diol;4,6-DIHYDROXY-2-MERCAPTOPYRIMIDINE;bathyran;austranal;usafek-660;2-Mercapto-4;Thiobarbituric
- CBNumber:
- CB5251676
- Molecular Formula:
- C4H4N2O2S
- Molecular Weight:
- 144.15
- MOL File:
- 504-17-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/13 14:26:59
| Melting point | 245 °C (dec.)(lit.) |
|---|---|
| Density | 1.451 (estimate) |
| refractive index | 1.7690 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | 50g/l slightly soluble |
| form | Liquid |
| pka | 3.96±0.20(Predicted) |
| color | Clear colorless |
| PH | 1.7-1.9 (10g/l, H2O, 20℃) |
| Water Solubility | <6 g/L (20 ºC) |
| BRN | 120663 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | RVBUGGBMJDPOST-UHFFFAOYSA-N |
| CAS DataBase Reference | 504-17-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 4,6(1H,5h)-pyrimidinedione, dihydro-2-thioxo-(504-17-6) |
| EPA Substance Registry System | 4,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo- (504-17-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-37/39-26 | |||||||||
| RIDADR | UN 3335 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | CQ7700000 | |||||||||
| F | 13-23 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29335995 | |||||||||
| NFPA 704 |
|
2-Thiobarbituric acid price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T5500 | 2-Thiobarbituric acid ≥98% | 504-17-6 | 25G | ₹3441 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T5500 | 2-Thiobarbituric acid ≥98% | 504-17-6 | 100G | ₹11488.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T5500 | 2-Thiobarbituric acid ≥98% | 504-17-6 | 250G | ₹20579.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T5500 | 2-Thiobarbituric acid ≥98% | 504-17-6 | 500G | ₹39826.8 | 2022-06-14 | Buy |
| TCI Chemicals (India) | T0192 | 2-Thiobarbituric Acid | 504-17-6 | 25G | ₹4800 | 2022-05-26 | Buy |
2-Thiobarbituric acid Chemical Properties,Uses,Production
Chemical Properties
Off-White to Yellow Powder. soluble in hot water, alcohol, ether, alkali and sodium carbonate solution, slightly soluble in water.
Uses
2-Thiobarbituric acid has been used to measure malondialdehyde (MDA) in lipid peroxidation assay.
Definition
ChEBI: 2-thiobarbituric acid is a barbiturate, the structure of which is that of barbituric acid in which the oxygen at C-2 is replaced by sulfur. It has a role as a reagent and an allergen.
Preparation
2-thiobarbituric acid was synthesized by the reaction of diethyl malonate with thiourea. Dissolve thiourea in methanol, add sodium methoxide and diethyl malonate, heat under reflux for 4-5h, then distill under reduced pressure to recover methanol to the end, and add hydrochloric acid to acidify to pH 1-2 after cooling. After standing overnight, thiobarbituric acid crystals were precipitated, filtered, and recrystallized with water to obtain the pure product.
General Description
2-Thiobarbituric acid is a molecule made up of heteroatoms: nitrogen, sulphur and oxygen.
Purification Methods
Crystallise it from water. [Beilstein 24 H 476, 24 I 414, 24 II 275, 24 III/IV 1884.]
2-Thiobarbituric acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 488)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Bhakti Impex | +919822268653 | Pune, India | 76 | 58 | Inquiry |
| Bhavesh Chem Labs | +91 9182312179 | Telangana, India | 322 | 58 | Inquiry |
| GRINDLAYS PHARMACEUTICALS PRIVATE LIMITED | +91-91-22-25278801 +91-2225278801 | Mumbai, India | 83 | 58 | Inquiry |
| SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 404 | 58 | Inquiry |
| Evans Fine Chem | +91-9821340302 +91-9821340302 | Maharashtra, India | 286 | 58 | Inquiry |
| Ronak Chemicals | +91-8141418480 +91-8141418480 | Gujarat, India | 14 | 58 | Inquiry |
| Cefa-Cilinas Biotics Pvt Ltd | +91-7875033155 +91-8080701561 | Maharashtra, India | 121 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Dhara Industries | +91-9322395199 +91-9322395199 | Mumbai, India | 190 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Bhakti Impex | 58 |
| Bhavesh Chem Labs | 58 |
| GRINDLAYS PHARMACEUTICALS PRIVATE LIMITED | 58 |
| SNECOFRi Pvt Ltd | 58 |
| Evans Fine Chem | 58 |
| Ronak Chemicals | 58 |
| Cefa-Cilinas Biotics Pvt Ltd | 58 |
| JSK Chemicals | 58 |
| Dhara Industries | 58 |
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504-17-6(2-Thiobarbituric acid)Related Search:
austranal
bathyran
Dihydro-2-thioxo-4,6-(1H,5H)-pyrimidinedione
dihydro-2-thioxo-4,6(1h,5h)-pyrimidinedione
Mealonylthiourea
Thiobarbituicacid
Thiobarbituric
2-THIOBARBITURICACID,REAGENT
2-MERCAPTO-4,6-DIHYDROXYPYRIMIDINE (2-THIOBARBITURIC ACID)
ThiobarbituricAcidGr
1-ThioglycerolGr90%
2-ThiobarbituricAcid98%
4,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo- (9CI)
4,6(1H,5H)-PYRIMIDINEDIONE, DIHYDRO-2-THIOXO-
4,6-DIHYDROXY-2-THIOPYRIMIDINE
4,6-DIHYDROXYPYRIMIDINE-2-THIOL
2-thiobarbituric acid minimum 98%
Thiobarbituric Acid, 2-
4,6-Dihydroxy-2-mercaptopyrimidine, 4,6-Dihydroxypyrimidine-2-thiol, TBA
2-Thio-4,6-dioxypyrimidine
2-Thioxo-6-hydroxy-1,2,3,4-tetrahydropyrimidine-4-one
6-Hydroxy-2-thioxo-1,2-dihydropyrimidin-4(3H)-one
2,3-Dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
4,6-Dihydroxy-2-mercaptopyrimidine,98%
3,4-Dihydroxy-2-mercaptopyrimidine
2-Thioxo-dihydro-pyrimidine-4,6-dione
usafek-660
4,6-Dihydroxypyrimidine-2-thiol ( 2-Thiobarbitursure)
2-THIOBARBITURIC ACIDANALYTICAL GRADE
MALONYLTHIOUREA
LABOTEST-BB LT00440785
AURORA KA-3842
2-MERCAPTO-4,6-DIHYDROXY-PYRIMIDINE
2-THIOBARBITURIC ACID
2-Mercapto-4
2-Thiobarbituric Acid [for BiocheMical Research]
4,6-Dihydroxy-2-MercaptopyriMidine, 98% 100GR
4,6-Dihydroxy-2-MercaptopyriMidine, 98% 5GR
4.6-Dihydroxy-2-mercaptopyrimidine 1g [504-17-6]
2-Thiobarbituric acid p.a.
4,6-Dihydroxy-2-merc
4,6-DihydroxypyriMidine-2-thiol (2-Thiobarbitursre)
2-THIOBARBITURIC ACID REAGENT FOR SORBIC
HexahydropyriMidine-4,6-dione-2-thione
Thiobarbituric aci
thiobarbituric acid (TBA)
2 - Mercapto - 4, 6-2 hydroxy pyriMidine
2-Thiobarbituric acid Vetec(TM) reagent grade, >=98%
2-Thiobarbituric acid(TBA)
2-Mercaptopyrimidine-4,6-dione
TIMTEC-BB SBB004132
2-mercaptobarbituricacid
2-thio-barbituricaci
5h)-pyrimidinedione,dihydro-2-thioxo-6(1h
6(1H,5H)-Pyrimidinedione,dihydro-2-thioxo-4
2-Thiobarbituric Acid >
2-Thiobarbituric acid ISO 9001：2015 REACH
2-Thiobarbituric acid 4,6-Dihydroxy-2-mercaptopyrimidine