Dithizone
- CAS No.
- 60-10-6
- Chemical Name:
- Dithizone
- Synonyms
- DIPHENYLTHIOCARBAZONE;dithizon;Dithizone (min. 98%);1,5-diphenyl-3-thiocarbazone;(E)-1,5-diphenylthiocarbazone;Diazenecarbothioic acid, 2-phenyl-, 2-phenylhydrazide;Ditizon;DITHIZONE;usafek-3092;DITHIZONE(P)
- CBNumber:
- CB5753569
- Molecular Formula:
- C13H12N4S
- Molecular Weight:
- 256.33
- MOL File:
- 60-10-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/14 18:30:21
| Melting point | 168 °C (dec.) (lit.) |
|---|---|
| Boiling point | 376.1±25.0 °C(Predicted) |
| Density | 1.2578 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | no restrictions. |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | pK1:4.50;pK2:15 (25°C) |
| form | Crystalline |
| color | Black powder |
| Water Solubility | Soluble in ethanol, chloroform, dimethylsulfoxide, and pyridine. Insoluble in water. |
| Merck | 14,3377 |
| BRN | 748838 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 60-10-6(CAS DataBase Reference) |
| EPA Substance Registry System | Diazenecarbothioic acid, phenyl-, 2-phenylhydrazide (60-10-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 36-26 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LQ9450000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29309090 | |||||||||
| NFPA 704 |
|
Dithizone price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D5130 | Dithizone Practical Grade | 60-10-6 | 10G | ₹4286.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D5130 | Dithizone Practical Grade | 60-10-6 | 50G | ₹14397.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 43820 | Dithizone ACS reagent, for spectrophotometric det. of Cd, Cu, Hg, Pb, Zn, ≥98.0% (TLC) | 60-10-6 | 10G | ₹6559.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 43820 | Dithizone ACS reagent, for spectrophotometric det. of Cd, Cu, Hg, Pb, Zn, ≥98.0% (TLC) | 60-10-6 | 50G | ₹19658.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 1.03092 | Dithizone for analysis (1,5-diphenylthiocarbazone) Reag. Ph Eur | 60-10-6 | 5G | ₹11480 | 2022-06-14 | Buy |
Dithizone Chemical Properties,Uses,Production
Chemical Properties
dark brown or black crystals
Uses
Dithizone is an organosulfur compound that acts as a chelating agent and forms complexes with metals such as lead and mercury. Dithizone is used to assess the purity of human pancreatic islet preparations used for transplantation into patients with type 1 diabetes.
General Description
Dithizone (Diphenylthiocarbazone) is used as chelating agent for zinc. It is widely used for the liquid-liquid and solid phase extraction of various metals since it forms stable complexes with the metals.
Purification Methods
The crude dithizone is dissolved in CCl4 to give a concentrated solution. This is filtered through a sintered glass funnel and shaken with 0.8M aqueous ammonia to extract dithizonate ion. The aqueous layer is washed with several portions of CCl4 to remove undesirable materials. The aqueous layer is acidified with dilute H2SO4 to precipitate pure dithizone. This is dried in a vacuum. When only small amounts of dithizone are required, purification by paper chromatography is convenient. [Cooper & Hibbits J Am Chem Soc 75 5084 1933.] Instead of CCl4, CHCl3 can be used, and the final extract, after washing with water, can be evaporated in air at 40-50o and dried in a desiccator. It complexes with Cd, Hg, Ni and Zn. [Beilstein 16 H 26, 16 IV 18.]
Dithizone Preparation Products And Raw materials
Raw materials
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Global( 355)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Bhakti Impex | +919822268653 | Pune, India | 76 | 58 | Inquiry |
| GRINDLAYS PHARMACEUTICALS PRIVATE LIMITED | +91-91-22-25278801 +91-2225278801 | Mumbai, India | 83 | 58 | Inquiry |
| Arnish Laborates Pvt Ltd | +91 7208475595 | Maharashtra, India | 187 | 58 | Inquiry |
| Dhara Industries | +91-9322395199 +91-9322395199 | Mumbai, India | 190 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| DeFINE CHEMICALS | +91-8010769889 +91-9320057099 | Maharashtra, India | 120 | 58 | Inquiry |
| Explicit Chemicals Pvt Ltd | +919822268653 | Maharashtra, India | 10 | 58 | Inquiry |
| Kemona Impex | 08068441141Ext 577 | Mumbai, India | 221 | 58 | Inquiry |
| Maitree Chemicals | 08048371810Ext 121 | Maharashtra, India | 29 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Bhakti Impex | 58 |
| GRINDLAYS PHARMACEUTICALS PRIVATE LIMITED | 58 |
| Arnish Laborates Pvt Ltd | 58 |
| Dhara Industries | 58 |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
| DeFINE CHEMICALS | 58 |
| Explicit Chemicals Pvt Ltd | 58 |
| Kemona Impex | 58 |
| Maitree Chemicals | 58 |
60-10-6(Dithizone)Related Search:
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Dithizone, for analysis (1,5-diphenylthiocarbazone) Reag.
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