1，2-Dimethyl hydrazine
- CAS No.
- 540-73-8
- Chemical Name:
- 1，2-Dimethyl hydrazine
- Synonyms
- Hydrazine, 1,2-dimethyl-;SDMH;1，2-Dimethyl hydrazine;Dimethyl hydrazine (symmetrical);Hydrazine, 1,2-dimethyl- (7CI,8CI,9CI)
- CBNumber:
- CB5852046
- Molecular Formula:
- C2H8N2
- Molecular Weight:
- 60.1
- MOL File:
- 540-73-8.mol
- Modify Date:
- 2024/3/14 15:18:27
| Melting point | -8.9°C |
|---|---|
| Boiling point | 87.05°C |
| Density | 0.8274 |
| refractive index | 1.4209 |
| pka | 9.29±0.70(Predicted) |
| Stability | Stable. Incompatible with oxidizing agents, water, moisture. |
| IARC | 2A (Vol. 4, Sup 7, 71) 1999 |
| EPA Substance Registry System | 1,2-Dimethylhydrazine (540-73-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H311-H331-H350-H411 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501 |
| Hazard Codes | T,N |
| Risk Statements | 45-23/24/25-51/53 |
| Safety Statements | 53-45-61 |
| RIDADR | 2382 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
1，2-Dimethyl hydrazine Chemical Properties,Uses,Production
Chemical Properties
colourless or yellow hygroscopic liquid which fumes in air
Uses
1,2-Dimethylhydrazine (SDMH) unlike its analog 1,1- dimethylhydrazine (UDMH) is used only in small quantities as a research chemical. There are no known commercial uses, although it was evaluated as a high-energy rocket fuel. The material is a fuming, strongly alkaline, moderately volatile liquid.
Definition
ChEBI: A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
General Description
A colorless liquid with an ammonia-like odor. Less dense than water. Flash point is 5°F. Contact irritate skin, eyes, and mucous membranes. Very toxic by ingestion, inhalation and skin absorption. Used to make photographic chemicals.
Air & Water Reactions
Highly flammable. Fumes upon exposure to air . Soluble in water with evolution of heat.
Reactivity Profile
1，2-Dimethyl hydrazine dissolves, swells, and disintegrates many plastics [USCG, 1999].
Health Hazard
Breathing of vapor causes pulmonary irritation, delayed gastro-intestinal irritation, tremors, and convulsions. Contact with skin or mucous membranes causes chemical burns. Can be absorbed through skin to cause systemic intoxication and convulsions.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and intramuscular routes. Moderately toxic by inhalation. Human mutation data reported. A very dangerous fire hazard when exposedto heat, flame, or oxidizers. A hgh-energy propellant for liquid-fueled rockets. When heated to decomposition it emits toxic fumes of NOx
Carcinogenicity
SDMH is carcinogenic to mice, rats, and hamsters using a variety of exposure routes. Oral doses of 21 mg/kg for 11 weeks produced intestinal tumors in rats. A lower dose (3 mg/kg) in drinking water for 12 months produced liver hemangioendotheliomas.A number of these tumors were metastatic. Mice given doses of 60–90 mg/day in drinking water developed a variety of tumors including angiosarcomas and lung adenomas . Both oral administration and intraperitoneal injection increased lung adenomas in the A/J strain mouse. Hamsters also developed angiosarcomas, intestinal tumors, and liver tumors following average daily intakes of 160 mg in drinking water. An in-depth description of the uniqueness of the colonic tumors was presented.
1，2-Dimethyl hydrazine Preparation Products And Raw materials
Raw materials
Preparation Products
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