ChemicalBook > Product Catalog >API >Antineoplastic agents >Antibiotics anticancer drugs >Bleomycin sulfate
Bleomycin sulfate
- CAS No.
- 9041-93-4
- Chemical Name:
- Bleomycin sulfate
- Synonyms
- BLEOMYCIN SULPHATE;BLENOXANE;Bleomycin Sulfate (mixture);BLEOMYCIN SULFATE CELL CULTURE TESTED;BLEO;BLEXANE;Bleolem;BLEOcell;BLEO cell;BLEO-cell
- CBNumber:
- CB8412175
- Molecular Formula:
- C110H168N34O46S7
- Molecular Weight:
- 2927.17
- MOL File:
- 9041-93-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/14 10:20:38
| Melting point | 200-204°C (dec.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: 20 mg/mL |
| form | powder |
| color | white |
| Water Solubility | Soluble in water or DMSO |
| Merck | 14,1318 |
| Stability | Stable for 1 year from the date of purchase. Solutions in distilled water may be stored at -20°C for up to 3 months. |
| InChIKey | OOXTWFJZZAJGKA-YWZNXBAZNA-N |
| CAS DataBase Reference | 9041-93-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H340-H351-H361fd | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 46-40-36/37/38-63 | |||||||||
| Safety Statements | 53-36/37-45-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | EC5991990 | |||||||||
| F | 10 | |||||||||
| HS Code | 2941906000 | |||||||||
| NFPA 704 |
|
Bleomycin sulfate price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B8416 | Bleomycin sulfate from Streptomyces verticillus 1.5-2.0?units/mg solid, BioReagent, suitable for cell culture | 9041-93-4 | 15UNITS | ₹112774.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B5507 | Bleomycin sulfate from Streptomyces verticillus crystalline, 1.5-2.0?U/mg | 9041-93-4 | 15UNITS | ₹92488.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B2434 | Bleomycin sulfate from Streptomyces verticillus BioXtra, crystalline | 9041-93-4 | 20MG | ₹131025.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 15361 | Bleomycin sulfate from Streptomyces verticillus for fluorescence, mixture of bleomycin sulfate salts, lyophilized, powder or crystals, white to off-white | 9041-93-4 | 1MG | ₹18196.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 15361 | Bleomycin sulfate from Streptomyces verticillus for fluorescence, mixture of bleomycin sulfate salts, lyophilized, powder or crystals, white to off-white | 9041-93-4 | 10MG | ₹83872.1 | 2022-06-14 | Buy |
Bleomycin sulfate Chemical Properties,Uses,Production
Chemical Properties
White Powder
Uses
Bleomycin sulfate binds to DNA, and can inhibit DNA synthesis and causes scission of DNA. Cleaves DNA, requires binding to oxygen and a metal ion, such as copper or iron. Able to cleave RNA, but at less and more selective degree. Also reported to induce and regulate apoptosis in a variety of cells, and inhibit tumor angiogenesis.
General Description
Bleomycin occurs as a white powder and is available in 15-and 30-U vials for reconstitution in water. It may be givenintravenously, intramuscularly, or subcutaneously. It is used in the treatment of squamous cell carcinoma of the headneck, cervix, penis, and vulva. It is also used in Hodgkin’sand non-Hodgkin’s lymphoma as well as testicular carcinoma.Unlabeled uses include the treatment of mycosis fungoides,osteosarcoma, and AIDS-related Kaposi sarcoma.
Clinical Use
Bleomycin is used IV in the palliative treatment of squamous cell head and neck cancers, testicular and other genital carcinomas, and Hodgkin's and non-Hodgkin's lymphoma.
Side effects
It is excreted via the kidneys, and serum concentrations of active drug are increased in patients with renal disease. The elimination half-life can rise from 2 to 4 hours to more than 20 hours in renal failure, resulting in significant toxicity, especially pulmonary toxicity.
Bleomycin sulfate Preparation Products And Raw materials
Raw materials
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Global( 446)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Bio Pharma Chemicals | 08069033785Ext 465 | Hyderabad, India | 32 | 58 | Inquiry |
| Merck Life Science Private Limited | 08046045443 | Mumbai, India | 101 | 58 | Inquiry |
| Triveni Interchem Private Limited (Group Of Triveni... | 08046042087 | Gujarat, India | 497 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
9041-93-4(Bleomycin sulfate)Related Search:
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Bleomycin sulfate, 1.5-2.0 units/mg
BLEOMYCIN SULFATE, BPC
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BleoMycin Sufate
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BleoMycin sulfate API
Blenoxane, Bleo, Blexane
Bleomycin Sulfate (15 mg)
Bleomycin Sulfate (A mixture of bleomycin sulfate salts) >90%
Bleomycin Sulfate (A mixture of bleomycin sulfate salts)
Bleomycin sulfate - mixture of Bleomycin A2, B2, B4
Blenoxane, Bleo
Blenmycins
bleomycin,sulfate(salt)
NSC-125066
BLEOMYCIN SULFATE, STREPTOMYCES VERTICILLUS
BLEXANE
BLEO
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BleoMycin Blenoxane
BLEOMYCIN SULFATE
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Bleomycin Sulfate (mixture)>
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Bleomycin sulfate USP/EP/BP
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Bleomycin Sulfate, Streptomyces verticillus - CAS 9041-93-4 - Calbiochem
Bleomycin sulfate - mixture of Bleomycin A2, B2
Bleomycin Sulfate (A mixture of bleomycin sulfate salts) >
Bleomycin Sulfate (mixture)
BLEOMYCIN SULFATE CELL CULTURE TESTED
BLEOMYCIN SULPHATE
BLENOXANE
inhibit,Bleomycin Sulfate,DNA/RNA Synthesis,Antibiotic,Bleomycin,Inhibitor
Bleomycin sulfate（1:x）
Bleomycin Sulfate, USP
BLEO cell
BLEOcell
BLEO-cell
Bleolem
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9041-93-4
C110H168N34O46S7
C55H84N17O21S3HSO4
C50H75N17O25S3
A2C55H84N17O21S3
2C55H84N17O21S3O4S
C55H85N17O25S4
C55H84O17N21S3