CARBOCROMEN

CARBOCROMEN Structure
CAS No.
804-10-4
Chemical Name:
CARBOCROMEN
Synonyms
D07619;Chromonar;CARBOCROMEN;carbochromen;carbochromene;Carbocromen (inn);Chromonar USP/EP/BP;CHROMONARHYDROCHLORIDE;Capolomon hydrochloride;KLOIYEQEVSIOOO-UHFFFAOYSA-N
CBNumber:
CB5771475
Molecular Formula:
C20H27NO5
Molecular Weight:
361.43
MOL File:
804-10-4.mol
Modify Date:
2023/5/4 17:34:42

CARBOCROMEN Properties

Melting point 220-222 °C
Boiling point 488.6±45.0 °C(Predicted)
Density 1.126±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka pKa 8.3 (Uncertain)
color Off-White

CARBOCROMEN price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PH003074 Ethyl ({3-[2-(diethylamino)ethyl]-4-methyl-2-oxo-2h-chromen-7-yl}oxy)acetate AldrichCPR 804-10-4 1MG ₹11983.28 2022-06-14 Buy
Product number Packaging Price Buy
PH003074 1MG ₹11983.28 Buy

CARBOCROMEN Chemical Properties,Uses,Production

Originator

Intensain,Hoechst,Switz,1963

Manufacturing Process

18.7 g of 3β-diethylaminoethyl-4-methyl-7-hydroxy-coumarin chlorhydrate are dissolved in 200 cc methyl ethyl ketone and 18 g anhydrous potassium carbonate are added. The mixture is stirred for 1 hour at 70°C and then 12 g bromoacetic acid ethyl ester are allowed to drop in. The reaction mixture is stirred under reflux for 9 hours and then it is filtered off with suction in the heat. The filtrate is concentrated in the vacuum to dryness and the resultant
residue is dissolved in ether. The etheric solution is washed with diluted caustic soda solution for several times and, subsequently, dried with Glauber's salt. By introduction of hydrochloric acid gas into the etheric solution the reaction product is precipitated in the form of chlorhydrate. Yield: 15 g of 3β- diethylaminoethyl-4-methylcoumarin-7-ethyl oxyacetate chlorhydrate having a melting point of 154° to 156°C (= 63% of the theory).
The starting material is produced by reacting resorcinol with 2-(2- diethylaminoethyl)acetic acid ethyl ester.

Therapeutic Function

Coronary vasodilator

CARBOCROMEN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 19)Suppliers
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CARBOCROMEN aceticacid,((3-(2-(diethylamino)ethyl)-4-methyl-2-oxo-2h-1-benzopyran-7-yl)ox carbochromen carbochromene Chromonar CHROMONARHYDROCHLORIDE [[3-[2-(Diethylamino)ethyl]-4-methyl-2-oxo-2H-1-benzopyran-7-yl]oxy]acetic acid ethyl ester 3-[2-(Diethylamino)ethyl]-4-methyl-2-oxo-α-chromen-7-yloxyacetic acid ethyl ester Carbocromen (inn) D07619 KLOIYEQEVSIOOO-UHFFFAOYSA-N Acetic acid, 2-[[3-[2-(diethylamino)ethyl]-4-methyl-2-oxo-2H-1-benzopyran-7-yl]oxy]-, ethyl ester Chromonar USP/EP/BP Capolomon hydrochloride 804-10-4 65-35-6 C20H27NO5 API