ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Quinoline compounds >3,4-DIHYDROQUINOLIN-2(1H)-ONE
3,4-DIHYDROQUINOLIN-2(1H)-ONE
- CAS No.
- 553-03-7
- Chemical Name:
- 3,4-DIHYDROQUINOLIN-2(1H)-ONE
- Synonyms
- 3,4-DIHYDRO-1H-QUINOLIN-2-ONE;HYDROCARBOSTYRIL;3,4-DIHYDRO-2(1H)-QUINOLINONE;inone;DIHYDROCARBOSTYRIL;dihydro-α-quinolone;3,4-Dihydrocarbostyril;3,4-Dihydro-2-quinolone;3,4-Dihydro-2(1H)-quinoL;3,4-Dihydro-2-quinolinone
- CBNumber:
- CB5772351
- Molecular Formula:
- C9H9NO
- Molecular Weight:
- 147.17
- MOL File:
- 553-03-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:03:02
| Melting point | 165-167 °C (lit.) |
|---|---|
| Boiling point | 267.28°C (rough estimate) |
| Density | 1.1135 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml |
| form | Crystalline Powder |
| pka | 14.76±0.20(Predicted) |
| color | Off-white |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Light Sensitive |
| Merck | 13,4800 |
| CAS DataBase Reference | 553-03-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301-H302-H315-H317-H319-H335 | |||||||||
| Precautionary statements | P280a-P301+P310a-P405-P501a-P261-P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38-43 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 2 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29337900 | |||||||||
| NFPA 704 |
|
3,4-DIHYDROQUINOLIN-2(1H)-ONE price More Price(2)
3,4-DIHYDROQUINOLIN-2(1H)-ONE Chemical Properties,Uses,Production
Chemical Properties
Off-white crystalline powder
Uses
3,4-Dihydro-2-(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments. It is used to prepare potent bicyclic peptide deformylase inhibitors with antibacterial effects. It is also used to synthesize substituted iminopiperidines as inhibitors of human nitric oxide synthase isoforms.
General Description
Series of 3,4-dihydro-2(1H)-quinolinone derivatives having sigma-1 receptor (σ1R) antagonist activity have been synthesized. 3,4-dihydro-2((1)H)-quinolinones have been synthesized using N-(1′-alkoxy)cyclopropyl-2-haloanilines as starting reagent. Cyclopropane ring expansion in the presence of palladium catalyst is the major step involved in the synthesis. Library of 3,4-dihydro-2(1H)-quinolinones have been synthesized through the rearrangement of β-lactam intermediates on the solid-phase
3,4-DIHYDROQUINOLIN-2(1H)-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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Global( 187)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Indus Biosciences Pvt. Ltd. | +91 (40) 2717-1045 | New Delhi, India | 43 | 50 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10259 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26368 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| CD Chemical Group Limited | +8615986615575 | China | 20356 | 58 | Inquiry |
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DIHYDROCARBOSTYRIL
3,4-DIHYDRO-2(H)-QUINOLINE
3,4-DIHYDRO-2(1H)-QUINOLONE
1,2,3,4-Tetrahydroquinolin-2-one
2-OXO-1,2,3,4-TETRAHYDROQUINOLINE
2-OXO-1,3,4-TRIHYDROQUINOLINE
dihydro-α-quinolone
o-aminohydrocinnamic acid lactam
3,4-Dihydrocarbostyril
3,4-DIHYDRO-1H-QUINOLIN-2-ONE, 99+%
2-Oxo-1,2,3,4-tetrahydroquinoline, 3,4-Dihydrocarbostyril
3,4-Dihydroquinolin-2(1H)-one 97%
4-Dihydro-2(1H)-quinolinone
3,4-Dihydro-2-quinolone
1,2,3,4-Tetrahydro-2(1H)-quinolinone
1,2,3,4-Tetrahydro-2-oxoquinoline
3,4-Dihydro-2-quinolinone
1,2,3,4-Tetrahydroquinoline-2-one
3,4-Dihydro-2(1H)-quinolinone,98%
3,4-Dihydro-2(1H)-quinolinoneHydrocarbostyril
2(1H)-Quinolinone, 3,4-dihydro-
3,4-Dihydro-2(1H)-quinolinone, 97+%
3,4-Dihydro-2(1H)-quinolinone 98%
3,4-Dihydro-2(1H)-quinoL
inone
1,2,3,4-Tetrahydroquinolin-2-one ISO 9001：2015 REACH
4-Tetrahydroquinolin-2-one
HYDROCARBOSTYRIL
3,4-DIHYDRO-2(1H)-QUINOLINONE
3,4-DIHYDRO-1H-QUINOLIN-2-ONE
3,4-DIHYDROQUINOLIN-2(1H)-ONE
553-03-7
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