PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT
- CAS No.
- 4265-07-0
- Chemical Name:
- PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT
- Synonyms
- PEP;PEP-K;PEP, potassium salt;PEP MONOPOTASSIUM SALT;POTASSIUM PHOSPHOENOLPYRUVATE;MONOPOTASSIUM PHOSPHOENOLPYRUVATE;PHOSPHOENOLPYRUVATE POTASSIUM SALT;PHOSPHO(ENOL)PYRUVATE MONOPOTASSIUM;1-carboxyethenyl hydrogen phosphate;Potassium Phosphoenol Pyruvate-2-13C
- CBNumber:
- CB5778797
- Molecular Formula:
- C3H4KO6P
- Molecular Weight:
- 206.13
- MOL File:
- 4265-07-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:11
| Melting point | 175 °C (dec.)(lit.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | solid |
| color | White to off-white |
| Water Solubility | Soluble in water. Slightly soluble in methanol. |
| Sensitive | Hygroscopic |
| BRN | 4603446 |
| CAS DataBase Reference | 4265-07-0(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Propenoic acid, 2-(phosphonooxy)-, monopotassium salt (4265-07-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29199000 | |||||||||
| NFPA 704 |
|
PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P7127 | Phospho(enol)pyruvic acid monopotassium salt ≥97% (enzymatic) | 4265-07-0 | 10MG | ₹2089.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P7127 | Phospho(enol)pyruvic acid monopotassium salt ≥97% (enzymatic) | 4265-07-0 | 100MG | ₹12784.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P7127 | Phospho(enol)pyruvic acid monopotassium salt ≥97% (enzymatic) | 4265-07-0 | 500MG | ₹20307.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P7127 | Phospho(enol)pyruvic acid monopotassium salt ≥97% (enzymatic) | 4265-07-0 | 250MG | ₹23858.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P7127 | Phospho(enol)pyruvic acid monopotassium salt ≥97% (enzymatic) | 4265-07-0 | 1G | ₹29465.65 | 2022-06-14 | Buy |
PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Chemical Properties,Uses,Production
Description
Phosphoenolpyruvic acid plays a role in both glycolysis and gluconeogenesis. During glycolysis, it is formed by the action of enolase on 2-phosphoglycerate and is metabolized to pyruvate by pyruvate kinase. One molecule of ATP is formed during its metabolism in this pathway. During gluconeogenesis, it is formed from phosphoenolpyruvate carboxykinase-catalyzed oxaloacetate decarboxylation and GTP hydrolysis. In plants, it is metabolized to form aromatic amino acids and also serves as a substrate for phosphoenolpyruvate carboxylase-catalyzed carbon fixation.
Chemical Properties
white to light yellow fine crystalline powder
Uses
Phosphoenolpyruvic acid monopotassium salt is used in glycolysis and gluconeogeneis. It is used for regeneration of ATP from ADP in enzyme-catalyzed syntheses. It is metabolized by an enzyme namely pyruvate kinase to yield pyruvate. It acts as protection against cell injury induced by oxidative stress and against dysfunction in carbohydrate metabolism.
General Description
Phospho(enol)pyruvic acid (PEP) acts as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase. It is a bifunctional carbohydrate, which exhibits antioxidant property. PEP may be a potential organ preservation agent in clinical transplantation.
Purification Methods
KPEP is purified via the monocyclohexylamine salt (see next entry). The salt (534mg) in H2O (10mL) is added to Dowex 50Wx4 H+ form (200-400 mesh, 2mL, H2O washed) and stirred gently for 30minutes and filtered. The resin is washed with H2O (6mL), and the combined solutions are adjusted to pH 7.4 with 3N KOH (~1.4mL) and the volume adjusted to 18.4mL with H2O to give a solution of 0.1M KPEP which can be lyophilised to a pure powder and is very good for enzyme work. It has been recrystallised from MeOH/Et2O. [Clark & Kirby Biochemical Preparations 11 103 1966, Wold & Ballou J Biol Chem 227 301 1957, Cherbuliez & Rabinowitz Helv Chim Acta 39 1461 1956, Beilstein 3 IV 977.] The triNa salt [5541-93-5] M 360.0, is purified as follows: the salt (1g) is dissolved in MeOH (40mL) and dry Et2O is added in excess. The white crystals are collected and dried over P2O5 at 20o. [Cramer & Voges Chem Ber 92 952 1959, Beilstein 3 IV 977.]
PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| R&D Scientific Inc. | +12266000236 | Canada | 1393 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 7287 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | China | 1328 | 58 | Inquiry |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | China | 12210 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Alfa Aesar | 58 |
| R&D Scientific Inc. | 58 |
| career henan chemical co | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | 58 |
| Chongqing Chemdad Co., Ltd | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | 58 |
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