ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Epigenetics >HDAC inhibitors >Tacedinaline
Tacedinaline
- CAS No.
- 112522-64-2
- Chemical Name:
- Tacedinaline
- Synonyms
- acetyldinaline;CI 994;CS-617;Cl-994;Goe 5549;PD 123654;CI994, >=99%;Tacedinaline;N-Acetyldinaline;CI994 (Tacedinaline)
- CBNumber:
- CB5855542
- Molecular Formula:
- C15H15N3O2
- Molecular Weight:
- 269.3
- MOL File:
- 112522-64-2.mol
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 216.1 °C |
|---|---|
| Boiling point | 450.6±30.0 °C(Predicted) |
| Density | 1.322±0.06 g/cm3(Predicted) |
| RTECS | CU8702023 |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Soluble in DMSO |
| pka | 13.15±0.70(Predicted) |
| form | powder |
| color | off-white |
| Sensitive | Air Sensitive |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| InChIKey | VAZAPHZUAVEOMC-UHFFFAOYSA-N |
Tacedinaline price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C0621 | CI−994 ≥98% (HPLC), powder | 112522-64-2 | 5MG | ₹12795.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C0621 | CI−994 ≥98% (HPLC), powder | 112522-64-2 | 25MG | ₹49849.13 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A2501 | Acetyldinaline | 112522-64-2 | 10MG | ₹4100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A2501 | Acetyldinaline | 112522-64-2 | 50MG | ₹10400 | 2022-05-26 | Buy |
Tacedinaline Chemical Properties,Uses,Production
Definition
ChEBI: A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Al o used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.
Biological Activity
Orally active histone deacetylase (HDAC) inhibitor (K i values are 0.41, 0.75, >100 and >100 μ M for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Mediates G 1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo .
Tacedinaline Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 196)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24722 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
112522-64-2(Tacedinaline)Related Search:
Benzamide, 4-(acetylamino)-N-(2-aminophenyl)-
Tacedinaline
CI 994
N-Acetyldinaline
4-AcetaMido-N-(2-aMinophenyl)benzaMide
Cl-994(Tacedinalin,N-Acetyldinalin)
CI994 (Tacedinaline)
CI-994 4-Acetylamino-N-(2'-aminophenyl)benzamide
Goe 5549
PD 123654
CI994, >=99%
4-acetylamino-n-(2'-aminophenyl)benzamide
CI 994 - PD 123654 | Tacedinaline
-aminophenyl)benzamide
PD-123654;CI-994;PD123654
CS-617
Cl-994
CI-994 (Acetyldinaline,PD123654)
4-Acetamido-N-(2-aminophenyl)benzamide >
Tacedinaline (CI994)
Tacedinaline USP/EP/BP
Tacedinaline (GOE-5549, PD-123654, CI-994
acetyldinaline
Goe5549,CI-994,Tacedinaline,inhibit,HDAC,CI 994,Inhibitor,Histone deacetylases,Apoptosis,Goe 5549
112522-64-2
Inhibitors
Inhibitor
Apoptosis Inducers