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PCI 34051

PCI 34051 Structure
CAS No.
950762-95-5
Chemical Name:
PCI 34051
Synonyms
PCI-34051;PCI 34051;PCI-34051;PCI 34051;PCI-34051, 10 mM in DMSO;N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide;1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide;N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide;N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide;1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]-
CBNumber:
CB52622953
Molecular Formula:
C17H16N2O3
Molecular Weight:
296.32
MOL File:
950762-95-5.mol
MSDS File:
SDS
Modify Date:
2025/4/17 18:22:24

PCI 34051 Properties

Density 1.25
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL in DMSO
form Powder
pka 9.16±0.30(Predicted)
color White to gray

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
NFPA 704
0
2 0

PCI 34051 Chemical Properties,Uses,Production

Uses

PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast.

PCI 34051 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 135)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 33024 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29808 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32239 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10473 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6391 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24727 58 Inquiry
TargetMol Chemicals Inc. United States 38648 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry

PCI 34051 Spectrum

N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide PCI 34051 PCI-34051 1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide 1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]- N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide PCI-34051;PCI 34051 N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide PCI-34051, 10 mM in DMSO 950762-95-5 Apoptosis Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Inhibitor