N-Isopropylbenzylamine
![N-Isopropylbenzylamine Structure](CAS/GIF/102-97-6.gif)
- CAS No.
- 102-97-6
- Chemical Name:
- N-Isopropylbenzylamine
- Synonyms
- Isopropylbenzylamine;Benzylisopropylamine;N-BENZYLISOPROPYLAMINE;N-benzylpropan-2-aMine;Benzylamine, N-isopropyl-;n-(1-methylethyl)-benzenemethanamine;AURORA KA-7714;N-Isopropylbenzylamine Crystal;n-(1-methylethyl)-benzenemethanamin;N-(1-Methylethyl)-benzeneMethanaMine hydrochloride
- CBNumber:
- CB9199936
- Molecular Formula:
- C10H15N
- Molecular Weight:
- 149.23
- MOL File:
- 102-97-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/29 11:33:17
Melting point | 143°C (estimate) |
---|---|
Boiling point | 200 °C(lit.) |
Density | 0.892 g/mL at 25 °C(lit.) |
refractive index |
n |
Flash point | 190 °F |
storage temp. | Store below +30°C. |
solubility | Chloroform (Slightly), Ethy Acetate (Slightly), Methanol (Slightly) |
form | Oil |
pka | 9.77±0.19(Predicted) |
color | Colourless |
BRN | 2638437 |
InChIKey | LYBKPDDZTNUNNM-UHFFFAOYSA-N |
CAS DataBase Reference | 102-97-6(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenemethanamine, N-(1-methylethyl)-(102-97-6) |
EPA Substance Registry System | Benzenemethanamine, N-(1-methylethyl)- (102-97-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
RIDADR | 2735 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29214980 | |||||||||
NFPA 704 |
|
N-Isopropylbenzylamine price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 8.41618 | N-Isopropylbenzylamine for synthesis | 102-97-6 | 100ML | ₹8620 | 2022-06-14 | Buy |
Sigma-Aldrich | 136964 | N-Isopropylbenzylamine 97% | 102-97-6 | 25G | ₹4254.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 136964 | N-Isopropylbenzylamine 97% | 102-97-6 | 25G | ₹4254.23 | 2022-06-14 | Buy |
TCI Chemicals (India) | B1216 | N-Isopropylbenzylamine min. 98.0 % | 102-97-6 | 25ML | ₹1800 | 2022-05-26 | Buy |
TCI Chemicals (India) | B1216 | N-Isopropylbenzylamine min. 98.0 % | 102-97-6 | 500ML | ₹9000 | 2022-05-26 | Buy |
N-Isopropylbenzylamine Chemical Properties,Uses,Production
Chemical Properties
CLEAR VERY SLIGHTLY YELLOW TO YELLOW LIQUID
Uses
N-Isopropylbenzylamine, can be used as an intermediate in the synthesis of pharmaceutical compounds,and as a precursor to the manufacture of some drugs. Due to it’s similarity in appearance and physical properties to methamphetamine, it has been recently come under consideration of DEA.
Application
N-Isopropylbenzylamine was used as ligand in the preparation and characterization of bis(cyclopentadienyl)magnesium. It was also used in the synthesis of N-benzylideneisopropylamine-N-oxide.
Preparation
N-benzylisopropylamine is synthesized by the reduction reaction of N-isopropylbenzamide or prepared from benzylamine and acetone by reductive amination reaction.
General Description
N-isopropylbenzylamine is a structural isomer of methamphetamine, is one of the most common adulterants. It forms amine adducts with magnesocene at ambient temperature in toluene.
Cytotoxicity
The toxicity of N-isopropylbenzylamine was evaluated in SH-SY5Y, PC12, and SN4741 cell lines. Cells were treated with 0.3–10 mM N-isopropylbenzylamine for 24 hours, and cell viability was measured using MTT assay. N-isopropylbenzylamine concentration-dependently reduced cell viability in these cells. The IC50 values of N-isopropylbenzylamine on cell viability were 3.47, 1.49, and 3.21 mM for SH-SY5Y cells, PC12 cells, and SN4741 cells, respectively. N-isopropylbenzylamine produced toxicity in cell lines that model neurons. Moreover, the activation of nNOS and the production of intracellular NO might be involved in N-isopropylbenzylamine-induced toxicity in SN4741 cells[1].
References
[1] Peng Xu . “N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro.” Toxicology 480 (2022): Article 153337.
N-Isopropylbenzylamine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Alkyl Amines Chemicals Limited | +91-91-22-24930710 +91-9075727921 | Mumbai, India | 65 | 58 | Inquiry |
CNS CHEMICALS | +91-9381957258 +91-9381957258 | Telangana, India | 354 | 58 | Inquiry |
Allchem Lifescience Pvt. Ltd | +919867655500 | Gujarat, India | 971 | 58 | Inquiry |
Dr Prem's Molecules Pvt. Ltd. | +91 9825310038 | New Delhi, India | 547 | 50 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Alkyl Amines Chemicals Limited | 09509697361 | Mumbai, India | 33 | 58 | Inquiry |
Trilok Enterprises | 08069033833Ext 392 | Karnataka, India | 25 | 58 | Inquiry |
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