PCI 34051
PCI 34051
- CAS:
- 950762-95-5
- MF:
- C17H16N2O3
- MW:
- 296.32
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Properties
- Density
- 1.25
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL in DMSO
- form
- Powder
- pka
- 9.16±0.30(Predicted)
- color
- White to gray
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H319
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P
- Hazard Codes
- Xn
- Risk Statements
- 22-36
- Safety Statements
- 26
Use
PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast.
0 India supplier list of "PCI 34051"
- Product Name: N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
- Products Intro:Purity: Min98% HPLC | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1KG