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Guanadrel

Guanadrel Structure
CAS No.
40580-59-4
Chemical Name:
Guanadrel
Synonyms
C07035;Guanadrel;Guanadrel USP/EP/BP;N-(1,4-Dioxaspiro[4.5]dec-2-ylmethyl)guanidine;1-(1,4-Dioxaspiro[4.5]decan-2-ylmethyl)guanidine;2-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)guanidine;Guanidine, N-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)-;2-((1,4-dioxaspiro[4.5]decan-2-yl)methyl)guanidine
CBNumber:
CB5875306
Molecular Formula:
C10H19N3O2
Molecular Weight:
213.28
MOL File:
40580-59-4.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:12
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Guanadrel Properties

Boiling point 341.5±40.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
form A solid
pka 12.59±0.70(Predicted)
color Colorless to light yellow

Guanadrel Chemical Properties,Uses,Production

Description

Guanadrel is an adrenergic neuron blocker used for essential hypertension. Its mechanism of action and side effects are similar to those of guanethidine.

Uses

Guanadrel is an adrenergic neuron blocker used for essential hypertension. The mechanism of action and side effects are similar to guanethidine. It is used for treating hypertension in patients who do not respond to thiazide diuretics. It can be used as an adjuvant drug in thiazide treatment for reaching an optimal level of blood pressure.

Definition

ChEBI: A spiroketal resulting from the formal condensation of the keto group of cyclohexanone with the hydroxy groups of 1-(2,3-dihydroxypropyl)guanidine. A postganglionic adrenergic blocking agent formerly used (generally as the sulfate salt) for the management f hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).

Guanadrel Preparation Products And Raw materials

Raw materials

2-Methyl-2-thiopseudourea sulfate

Preparation Products

Guanadrel Suppliers

Global( 21)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9030 58 Inquiry
Nanjing Doge Biomedical Technology Co., Ltd +86-25-58227606 +86-15305155328 China 4128 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 China 39997 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
Taizhou Nanfeng Pharmaceutical Research Institute 18616377689 China 20566 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Amel Pharmatech Corporation 888-4366503 China 5351 58 Inquiry
Supplier Advantage
Career Henan Chemica Co 58
Shaanxi Dideu Medichem Co. Ltd 58
Nanjing Doge Biomedical Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
LEAPCHEM CO., LTD. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
TargetMol Chemicals Inc. 58
Taizhou Nanfeng Pharmaceutical Research Institute 58
Cayman Chemical Company 81
Amel Pharmatech Corporation 58

40580-59-4(Guanadrel)Related Search:

(2,2-DIMETHYL-[1,3]-DIOXOLAN-4-YL)-METHYLAMINE Guanadrel Guanadrel HeMisulfate 2-methyl-1,4-dioxaspiro[4.5]decane 1,4-Dioxaspiro[4.5]decane-2-methanamine
Guanadrel 1-(1,4-Dioxaspiro[4.5]decan-2-ylmethyl)guanidine C07035 N-(1,4-Dioxaspiro[4.5]dec-2-ylmethyl)guanidine 2-((1,4-dioxaspiro[4.5]decan-2-yl)methyl)guanidine 2-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)guanidine Guanidine, N-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)- Guanadrel USP/EP/BP 40580-59-4