Guanadrel HeMisulfate
- CAS No.
- 22195-34-2
- Chemical Name:
- Guanadrel HeMisulfate
- Synonyms
- Anarel;Hylorel;U-28288D;CL-1388R;Hyloride;CHEBI:5556;Guanadrel HeMisulfate;GUANADREL SULFATE (200 MG);(1,4-Dioxaspiro[4.5]dec-2-ylMethyl)guanidine Sulfate;N-(1,4-Dioxaspiro[4.5]dec-2-ylMethyl)guanidine Sulfate
- CBNumber:
- CB5501416
- Molecular Formula:
- C10H19N3O2.H2O4S
- Molecular Weight:
- 311.357
- MOL File:
- 22195-34-2.mol
- Modify Date:
- 2022/12/21 16:56:50
Guanadrel HeMisulfate Chemical Properties,Uses,Production
Uses
Guanadrel is an orally active postganglionic sympathetic inhibitor. Guanadrel HeMisulfate is used as an antihypertensive.
Definition
ChEBI: A sulfate salt resulting from the reaction of 2 eq. guanadrel with 1 eq. sulfuric acid. A postganglionic adrenergic blocking agent formerly used for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthosta ic hypotension (dizzy spells on standing up or stretching).
General Description
Guanadrel sulfate, (1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanadine sulfate (Hylorel), issimilar to guanethidine monosulfate in the manner in whichit reduces elevated blood pressure. It acts as a postganglionicadrenergic blocking agent by displacing norepinephrinein adrenergic neuron storage granules, therebypreventing release of the endogenous neurotransmitter onnerve stimulation. Guanadrel sulfate has a much shorterhalf-life (10 hours) than guanethidine monosulfate, whose half-life is measured in days. In the stepped-care approachto hypertension, guanadrel sulfate is usually a step 2 agent.
Guanadrel HeMisulfate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Energy Chemical | 021-58432009 400-005-6266 | China | 44843 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 4008200310 | China | 24017 | 58 | Inquiry |
| Whyte Chemicals | +44 (20) 8346-5946 | United Kingdom | 3755 | 50 | Inquiry |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | China | 94717 | 76 | Inquiry |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | China | 56057 | 58 | Inquiry |
| Nantong Chem-Tech.(Group) Co., Ltd | 0086-513-85081108 85335860 | Europe | 1812 | 56 | Inquiry |
| Waterstone Technology, LLC | 317 644 0862 | United States | 6801 | 30 | Inquiry |