Agmatine sulfate
- CAS No.
- 2482-00-0
- Chemical Name:
- Agmatine sulfate
- Synonyms
- AGMATINE SULPHATE;2-(4-aminobutyl)guanidine,sulfuric acid;gmatine sulfate;agmatine sulfate salt;1-AMINO-4-GUANIDINOBUTANE SULFATE SALT;ARGAMINE;matine SuL;Agmatine SuL;Agmatine sulfat;AGMATINE SULFATE
- CBNumber:
- CB7421831
- Molecular Formula:
- C5H16N4O4S
- Molecular Weight:
- 228.27
- MOL File:
- 2482-00-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/16 10:38:43
| Melting point | 234-238 °C(lit.) |
|---|---|
| RTECS | ME8413000 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: 50 mg/mL |
| form | powder |
| color | white to off-white |
| Water Solubility | Soluble in water, nearly insoluble in alcohol |
| Merck | 14,188 |
| BRN | 3918807 |
| InChI | InChI=1S/C5H14N4.H2O4S/c6-3-1-2-4-9-5(7)8;1-5(2,3)4/h1-4,6H2,(H4,7,8,9);(H2,1,2,3,4) |
| InChIKey | PTAYFGHRDOMJGC-UHFFFAOYSA-N |
| SMILES | C(CCCN)NC(N)=N.S(O)(O)(=O)=O |
| CAS DataBase Reference | 2482-00-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HS Code | 29252900 | |||||||||
| NFPA 704 |
|
Agmatine sulfate price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A7127 | Agmatine sulfate salt ≥97%, powder | 2482-00-0 | 1G | ₹7014.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A7127 | Agmatine sulfate salt ≥97%, powder | 2482-00-0 | 5G | ₹27571.28 | 2022-06-14 | Buy |
| ALFA India | ALF-H55363-MD | Agmatine sulfate, 97% | 2482-00-0 | 250mg | ₹1340 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A0310 | Agmatine Sulfate | 2482-00-0 | 100MG | ₹2100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A0310 | Agmatine Sulfate | 2482-00-0 | 1G | ₹3600 | 2022-05-26 | Buy |
Agmatine sulfate Chemical Properties,Uses,Production
Description
Agmatine sulfate is the sulfate of the Agmatine. Agmatine is an aninoguanidine that is naturally derived from the arginine. It can exert modulatory effect on many molecular targets such as neurotransmitter systems, opioid analgesia, ion channels, and nitric oxide (NO) synthesis and polyamine metabolism. It has been also found that it can reverse the pain induced from inflammation, neuropathy, and spinal cord injury. Those effects make it a potential candidate for multiple pharmacological applications in the future.
Chemical Properties
White to off-white powder
Uses
Agmatine Sulfate is a a polyamine derived from L-arginine (A769500) decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine a t α2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects.
Biological Activity
Arginine metabolite that is synthesized within bovine brain and exhibits clonidine-displacing substance (CDS) activity. Putative endogenous ligand for the imidazoline binding site.
Purification Methods
Crystallise the salt from aqueous MeOH. The free base has m 101.5-103o, the gold chloride hydrochloride crystallises from H2O with m 223o(dec), and the picrate has m 236-238o. [Odo J Chem Soc Jpn 67 132 1946, Beilstein 4 I 420, 4 II 703, 4 III 575, 4 IV 1291.]
References
Fairbanks, C. A., et al. "Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury." Proceedings of the National Academy of Sciences of the United States of America97.19(2000):10584.
Kolesnikov, Yuri, S. Jain, and G. W. Pasternak. "Modulation of opioid analgesia by agmatine." European Journal of Pharmacology296.1(1996):17-22.
Su, R. B., J. Li, and B. Y. Qin. "A biphasic opioid function modulator: agmatine. "Acta Pharmacologica Sinica24.7(2003):631.
Galea, Elena, et al. "Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine." Biochemical Journal 316 ( Pt 1).1(1996):247.
https://en.wikipedia.org/wiki/Agmatine
Agmatine sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Gold Gym | 08607164824 | Uttar Pradesh, India | 1 | 58 | Inquiry |
| Hitech Pharma | 08068979693Ext 225 | Ahmedabad, India | 2 | 58 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
| Gold Gym | 58 |
| Hitech Pharma | 58 |
| Reax Chemicals | 58 |
| Pharma Affiliates | 58 |
| Clearsynth Labs | 58 |
2482-00-0(Agmatine sulfate )Related Search:
1of4
chevron_right