ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Metabolism >Transferase Inhibitors >Tipifarnib
Tipifarnib
- CAS No.
- 192185-72-1
- Chemical Name:
- Tipifarnib
- Synonyms
- R115777;CS-2330;IND 58359;Zarnestra;ipifarnib;TIPIFARNIB;NSC-702818;(R)-(+)-R 115777;Tipifarnib(R115777);TIPIFARNIB ZARNESTRA
- CBNumber:
- CB61011759
- Molecular Formula:
- C27H22Cl2N4O
- Molecular Weight:
- 489.4
- MOL File:
- 192185-72-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
| Melting point | 211-213°C (dec.) |
|---|---|
| Boiling point | 681.7±55.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 7.20±0.10(Predicted) |
| form | powder |
| color | white to beige |
| optical activity | [α]/D 17 to 24°, c = 1 in methanol |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P305+P351+P338 |
| HS Code | 2933790090 |
Tipifarnib price More Price(2)
Tipifarnib Chemical Properties,Uses,Production
Chemical Properties
Off-White to Pale Beige Solid
General Description
Pre-clinical studies show that tipifarnib has antiproliferative effects on pancreatic cancer cell lines at clinically relevant concentrations (concentration that inhibits 50% growth [IC50] from 9.5 to 500?nmol/L). It also exhibits marked growth retardation and antiangiogenic effects in a pancreatic cancer xenograft model.
Tipifarnib Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 160)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | China | 29730 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29858 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32202 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 22854 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10473 | 58 | Inquiry |
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TIPIFARNIB
TIPIFARNIB ZARNESTRA
(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
Zarnestra
(R)-(+)-R 115777
6-[(R)-AMino(4-chlorophenyl)(1-Methyl-1H-iMidazol-5-yl)Methyl]-4-(3-chlorophenyl)-1-Methyl-2(1H)-quinolinone
Tipifarnib(Zarnestra,NSC-702818, R-115777)
IND 58359
R115777
Tipifarnib(R115777)
(R)-6-(amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one
Tipifarnib (IND 58359
ipifarnib
CS-2330
ZARNESTRA; IND 58359; R115777; IND-58359; IND58359; R-115777; R 115777
Tipifarnib (Zarnestra) IND 58359, R115777
2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-
Tipifarnib USP/EP/BP
6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one
Tipifarnib, 10 mM in DMSO
NSC-702818
192185-72-1
192185-71-4
Inhibitors
Amines
Aromatics
Heterocycles
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Pharmaceuticals
Tyrosine Kinase Inhibitors
Inhibitor
Antineoplastic