Oxandrolone
- CAS No.
- 53-39-4
- Chemical Name:
- Oxandrolone
- Synonyms
- Anavar;Oxandrolone (Anavar);17BETA-HYDROXY-17-METHYL-2-OXA-5ALPHA-ANDROSTAN-3-ONE;8075cb;sc11585;Lonavar;Vasorome;SC 11585;Provitar;Protivar
- CBNumber:
- CB6112482
- Molecular Formula:
- C19H30O3
- Molecular Weight:
- 306.44
- MOL File:
- 53-39-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/30 16:33:02
| Melting point | 235-238°C |
|---|---|
| alpha | D25 -23° (c = approx 1% in chloroform) |
| Boiling point | 387.04°C (rough estimate) |
| Density | 1.0829 (rough estimate) |
| refractive index | 1.4200 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble2mg/mL (clear solution; warmed) |
| form | powder |
| pka | 15.15±0.60(Predicted) |
| color | white to beige |
| optical activity | [α]/D -19 to -26°, c = 1 (CDCl3) |
| Merck | 6921 |
| InChIKey | QSLJIVKCVHQPLV-PEMPUTJUSA-N |
| CAS DataBase Reference | 53-39-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Oxandrolone(53-39-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H351-H360FD | |||||||||
| Precautionary statements | P201-P308+P313 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 60-63-20/21/22 | |||||||||
| Safety Statements | 22-36/37/39-45 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | RN6800700 | |||||||||
| HS Code | 2937290000 | |||||||||
| Toxicity | LD50 oral in rabbit: > 5gm/kg | |||||||||
| NFPA 704 |
|
Oxandrolone Chemical Properties,Uses,Production
Description
Oxandrolone is a synthetic anabolic-androgenic steroid. It is a 17 alpha-methylated version of dihydrotestosterone (DHT). It can be used for the treatment of many kinds of disorders such as idiopathic short stature, body mass loss due to catabolic illness, severe burns, trauma and hereditary angioedema as well as turner syndrome. Oxandrolone is especially effective in the treatment of severe burns without causing obvious side effects. It acts as an agonist of the androgen receptor, which modulates related gene expression to increase protein synthesis, further boosting muscle growth and increasing body mass as well as bone mineral density. However, it should be noted that its androgenic effect is less than its anabolic effect.
Chemical Properties
white Solid. Soluble in chloroform, slightly soluble in ethanol, acetone, slightly soluble in ether, very slightly soluble in water.
Uses
Oxandrolone is used for the same indications as nandrolone. It is a synthetic, anabolic steroid. Used to promote muscle growth and combat involuntary weight loss. It has also been used to treat cases of osteoporosis.
General Description
Oxandrolone, 17β-hydroxy-17-methyl-2-oxaandrostan-3-one, is approved to aid in the promotionof weight gain after weight loss following surgery,chronic infections, or severe trauma and to offset protein catabolismassociated with long-term corticosteroid use.Oxandrolone is also used to relieve bone pain accompanyingosteoporosis. It has been used to treat alcoholic hepatitisand HIV wasting syndrome.
Safety Profile
Moderately toxic by ingestion andintraperitoneal routes. Experimental reproductive effects.When heated to decomposition it emits acrid smoke andfumes.
References
Li, H., et al. "The efficacy and safety of oxandrolone treatment for patients with severe burns: A systematic review and meta-analysis. " Burns Journal of the International Society for Burn Injuries 42.4(2016): 717.
Hart, D. W., et al. "Anabolic effects of oxandrolone after severe burn." Annals of Surgery 233.4(2001): 556-564.
Sheffieldmoore, M, et al. "Short-term oxandrolone administration stimulates net muscle protein synthesis in young men. " Journal of Clinical Endocrinology & Metabolism 84.8(1999): 2705-11.
https://en.wikipedia.org/wiki/Oxandrolone
Oxandrolone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Max Supplement | 08046048373 | Delhi, India | 1 | 58 | Inquiry |
| The Nikilakarnataka Central Ayurvedic Pharmacy | 08068441087Ext 183 | Karnataka, India | 1 | 58 | Inquiry |
| Blushing Beauty | 08048987521 | Delhi, India | 2 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | +8618068519287 | China | 833 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | China | 3582 | 58 | Inquiry |
| Hebei Endun Biological Technology Co. LTD | +86-8615932657220 +86-15932657220 | China | 300 | 58 | Inquiry |
| Doublewin Biological Technology Co., Ltd | +86-19971437628 | China | 97 | 58 | Inquiry |
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