ACYCLOVIR-D4
- CAS No.
- 1185179-33-2
- Chemical Name:
- ACYCLOVIR-D4
- Synonyms
- Zyclir-d4;Zovirax-d4;Herpevir-d4;Gerpevir-d4;Cargosil-d4;ACYCLOVIR-D4;Acicloftal-d4;Acycloguanosine-d4;Acyclovir Impurity 18;Cytarabine Impurity 60
- CBNumber:
- CB6128250
- Molecular Formula:
- C8H7D4N5O3
- Molecular Weight:
- 229.23
- MOL File:
- Mol file
- Modify Date:
- 2023/6/8 9:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
ACYCLOVIR-D4 Chemical Properties,Uses,Production
Description
Acyclovir-d4 is intended for use as an internal standard for the quantification of acyclovir by GC- or LC-MS. Acyclovir is a guanosine analog that has antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1-63.1 μM). It diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a virus-specific thymidine kinase. During DNA replication, the phosphorylated form of acyclovir is preferentially incorporated into viral DNA, resulting in premature chain termination and inhibition of further DNA polymerase activity. Acyclovir (5 mg/kg) reduces viral titers in mice infected with the herpes simplex virus-1 (HSV-1) strain SC16.
Chemical Properties
Colourless Powder
Uses
Acyclovir-d4can be ued as orally active acyclic labelled nucleoside with inhibitory activity towards several herpes viruses.
ACYCLOVIR-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Shanghai Saikerui Biotechnology Co. , Ltd. | 021-58000709 15900491054 | China | 9268 | 58 | Inquiry |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | China | 12584 | 58 | Inquiry |
| Xi'an Ruipuyuan Biotechnology Co., Ltd | 18909235869 18909235890 | China | 155 | 58 | Inquiry |
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