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3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE

3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Structure
CAS No.
335165-68-9
Chemical Name:
3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE
Synonyms
BAX CHANNEL BLOCKER;Bax channel blocke;)-3-(piperazin-1-yL;Baxchannelblocker2HCl;1-(3,6-Dibromo-9H-carbazoL;Bax channel blocker(BAI-1);BAI1 (Bax channel blocker);9H-Carbazole-9-ethanol, 3,6-dibromo-α-(1-piperazinylmethyl)-;1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(piperazin-1-yl)propan-2-ol;"(+/-)-1-(3,6-dibromocarbazol-9-yl)-3-piperazin-1-ylpropan-2-ol"
CBNumber:
CB6143286
Molecular Formula:
C19H21Br2N3O
Molecular Weight:
467.2
MOL File:
335165-68-9.mol
Modify Date:
2023/5/18 11:31:05
Request For Quotation

3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Properties

Boiling point 388.1±42.0 °C(Predicted)
Density 1.71±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility ≥28.2 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O
form solid
pka 14.48±0.20(Predicted)
color White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Chemical Properties,Uses,Production

Biological Activity

Potent inhibitor of Bax-mediated mitochondrial cytochrome c release (IC 50 = 0.52 μ M). Suggested to inhibit Bax channel formation/activity.

3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

1-Piperazinecarboxylic acid, 4-[(2S)-3-(3,6-dibromo-9H-carbazol-9-yl)-2-hydroxypropyl]-, 1,1-dimethylethyl ester 1-Piperazinecarboxylic acid, 4-[(2R)-3-(3,6-dibromo-9H-carbazol-9-yl)-2-hydroxypropyl]-, 1,1-dimethylethyl ester

Preparation Products

3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Suppliers

Global( 74)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd +86-86-22-87899925 +86-8618522618860 China 694 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
ATK CHEMICAL COMPANY LIMITED 60
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd 58
Career Henan Chemica Co 58
InvivoChem 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
LEAPCHEM CO., LTD. 58

3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Spectrum

3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE(335165-68-9)1HNMR

335165-68-9(3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE)Related Search:

Carbazole-9-ethanol 3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE 5-Bromo-1-methyl-1H-indole 1-(4-[2-HYDROXY-3-(1,3,6-TRIBROMO-9H-CARBAZOL-9-YL)PROPYL]PIPERAZINO)-3-(1,3,6-TRIBROMO-9H-CARBAZOL-9-YL)PROPAN-2-OL DIHYDROCHLORIDE 3,6-Dibromo-9-ethylcarbazole
3-Bromo-9H-carbazole 3-(1H-INDOL-1-YL)PROPAN-1-AMINE HYDROCHLORIDE 5-BROMO-1-ETHYL-1H-INDOLE 1-PROPYL-PIPERAZINE MONOHYDROBROMIDE 1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL
1-N-PROPYLPIPERAZINE DIHYDROBROMIDE 3,6-Dibromocarbazole
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Baxchannelblocker2HCl 3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE 3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanoldihydrochloride Bax channel blocke Bax channel blocker(BAI-1) 1-(3,6-Dibromo-9H-carbazoL 9H-Carbazole-9-ethanol, 3,6-dibromo-α-(1-piperazinylmethyl)- )-3-(piperazin-1-yL 1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(piperazin-1-yl)propan-2-ol BAI1 (Bax channel blocker) "(+/-)-1-(3,6-dibromocarbazol-9-yl)-3-piperazin-1-ylpropan-2-ol" BAX CHANNEL BLOCKER Inhibitor,mitochondrial,cell,inhibit,BAI1,effector,BAI 1,critical,BAX,death,BAI-1,Bcl-2 Family,pathway,Apoptosis 335165-68-9 335165-69-9 C19H21Br2N3O2HCl Caspases/Apoptosis Apoptosis Inhibitors