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5-Bromo-2-chloropyridine

CAS No.: 53939-30-3

Chemical Name:: 5-Bromo-2-chloropyridine

Synonyms: N-methyl-1-(pyridin-3-yl)methanamine;CL025;2-cholro-5-broMopyridine;2-CHLORO-5-BROMOPYRIDINE;5-BROMO-2-CHLOROPYRIDINE;3-Bromo-6-chloropyridine;5-Bromo-2-chloro pyridne;5-bromo-2-chlorolpyridine;PYRIDINE, 5-BROMO-2-CHLORO-;2-chloro -5-pyridyl broMide

CBNumber:: CB6177511

Molecular Formula:: C5H3BrClN

Molecular Weight:: 192.44

MOL File:: 53939-30-3.mol

MSDS File:: SDS

Modify Date:: 2023/10/30 12:13:21

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5-Bromo-2-chloropyridine Properties

Melting point	65-69 °C (lit.)
Boiling point	208.1±20.0 °C(Predicted)
Density	1.7783 (rough estimate)
refractive index	1.5400 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	-2.25±0.10(Predicted)
form	Crystalline Powder or Crystals
color	Off-white
BRN	108887
InChI	InChI=1S/C5H3BrClN/c6-4-1-2-5(7)8-3-4/h1-3H
InChIKey	PEAOEIWYQVXZMB-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=C(Br)C=C1
CAS DataBase Reference	53939-30-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39-36/37/39

WGK Germany

Hazard Note

Irritant

TSCA

HazardClass

IRRITANT, IRRITANT-HARMFUL

HS Code

29333990

NFPA 704

	1
2		0

5-Bromo-2-chloropyridine price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	551902	5-Bromo-2-chloropyridine 95%	53939-30-3	5G	₹1569.63	2022-06-14	Buy
Sigma-Aldrich	551902	5-Bromo-2-chloropyridine 95%	53939-30-3	25G	₹6191.9	2022-06-14	Buy
Sigma-Aldrich(India)	551902	5-Bromo-2-chloropyridine 95%	53939-30-3	25G	₹6191.9	2022-06-14	Buy
TCI Chemicals (India)	B2329	5-Bromo-2-chloropyridine min. 98.0 %	53939-30-3	5G	₹2100	2022-05-26	Buy
ALFA India	ALF-B24862-14	5-Bromo-2-chloropyridine, 98%	53939-30-3	25g	₹2702	2022-05-26	Buy

Product number	Packaging	Price	Buy
551902	5G	₹1569.63	Buy
551902	25G	₹6191.9	Buy
551902	25G	₹6191.9	Buy
B2329	5G	₹2100	Buy
ALF-B24862-14	25g	₹2702	Buy

5-Bromo-2-chloropyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow Cryst

Uses

5-Bromo-2-chloropyridine may be used in the preparation of following compounds:

Amino-2-chloropyridine via palladium-catalyzed amination.
5-Bromo-2-fluoropyridine via halogen-exchange reaction using anhydrous potassium fluoride.
2-Chloro-5-(2,5-dimethoxyphenyl)pyridine via Suzuki coupling with 2,5-dimethoxyphenylboronic acid.

Synthesis

6-Chloro-pyridin-3-ylamine was dissolved slowly with constant stirring in 48% HBr solution (50 mL) at r.t. and then the solution was cooled to -10 °C. A solution of sodium nitrite in cold water was added dropwise at -10 °C with constant stirring over 2 h, followed by a solution of copper (I) bromide in 48% HBr dropwise. The mixture was then stirred at r.t. until complete. The mixture was neutralized with sodium carbonate and extracted with ethyl acetate. The organic phase was washed with brine, dried over sodium sulfate, and concentrated. The residue was purified by column chromatography on silica gel (60-120 mesh) eluting with 1% ethyl acetate/petroleum ether to afford 5- bromo-2-chloropyridine.
5-Bromo-2-chloropyridine

5-Bromo-2-chloropyridine Preparation Products And Raw materials

Raw materials

3-Bromo-4-chloropyridine 5-BROMO-1-METHYL-2(1H)-PYRIDINONE 5-Bromo-2-chloropyridine N-oxide 3-Bromo-2-chloropyridine 3-BROMOPYRIDINE-N-OXIDE

Preparation Products

2-Chloropyridine-5-boronic acid 5-Bromo-2-chloro-4-iodopyridine 3-Bromo-6-mercaptopyridine 4-BOC-1-(5-BROMO-2-PYRIDYL)PIPERAZINE 5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE

tert-Butyl 4-(6-chloropyridin-3-yl)piperazine-1-carboxylate

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5-Bromo-2-chloropyridine Suppliers

Global( 598)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
GLR Innovations	+91 9891111994	New Delhi, India	4542	58	Inquiry
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Varna Chems	+91-9030000693 +91-9030000693	Hyderabad, India	483	58	Inquiry
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Sintilla Medcoms Pvt Ltd	+91-4027808001 +91-8886733867	Telangana, India	307	58	Inquiry

Supplier	Advantage
GLR Innovations	58
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED	58
Varna Chems	58
SVH BIOSCIENCES	58
JUVENUS DRUGS	58
Lorven therapeutics Pvt Ltd	58
VGS SYNTHESIS PRIVATE LIMITED	58
CHATURYA BIOTECH	58
JSK Chemicals	58
Sintilla Medcoms Pvt Ltd	58

5-Bromo-2-chloropyridine Spectrum

5-Bromo-2-chloropyridine(53939-30-3)MS 5-Bromo-2-chloropyridine(53939-30-3)¹HNMR 5-Bromo-2-chloropyridine(53939-30-3)¹³CNMR 5-Bromo-2-chloropyridine(53939-30-3)IR1 5-Bromo-2-chloropyridine(53939-30-3)IR2

53939-30-3(5-Bromo-2-chloropyridine)Related Search:

1-Hexadecylpyridinium bromide 2-Chloro-5-chloromethylpyridine Clopidol 2-Chloro-5-fluoropyridine 2-Chloro-3-cyanopyridine

5-Amino-2-chloropyridine 2-chloro-5-cyanopyridine 3-Bromo-6-chloro-2-methylpyridine 6-Chloro-2-methyl-3-nitropyridine 2-Chloro-5-hydroxypyridine

2-CHLORO-5-METHOXYPYRIDINE 2-Chloro-5-nitropyridine 2-Chloro-5-iodopyridine 5-Bromo-2-chlorobenzoic acid pyridinium Chlorochromate

Difluorochloromethane Bromine 2-Chloropyridine

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5-BROMO-2-CHLOROPYRIDINE 2-CHLORO-5-BROMOPYRIDINE PYRIDINE, 5-BROMO-2-CHLORO- 3-Bromo-6-chloropyridine 5-bromo-2-chlorolpyridine 5-Bromo-2-chloropyridine, 98+% 5-BROMO-2-CHLOROPYRIDINE 98% 2-CHLORO-5-BROMOPYRIDINE 5-BROMO-2-CHLORO-PYRIDINE 5-Bromo-2-chloropyridine 2-Chloro-5-Bromopyridine 2-cholro-5-broMopyridine 2-chlorine-5- broMine Pyridine 2-chloro -5-pyridyl broMide 5-broMo -2-chlorine pyridine 5-BroMo-2-chloropyridine, 97+% CL025 2-CHLORO-5-BROMOPYRIDINE 5-BROMO-2-CHLORO-PYR 5-Bromo-2-chloro pyridne 5-Bromo-2-chloropyridine > 5-Bromo-2-chloropyridine ISO 9001：2015 REACH N-methyl-1-(pyridin-3-yl)methanamine 53939-30-3 53930-30-3 52939-30-3 C5H3BrClN Pyridines Heterocyclic Building Blocks Halogenated Heterocycles Building Blocks Chloropyridines Halopyridines Bromopyridines Pyridines derivates Halogenated Organohalides Bromopyridines Chloropyridines Halopyridines Boronic Acid C5Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Variety of halogenated heterocyclic series blocks Bromides Pyridines Pyridine pyridine derivative Pyridine Series Pyridines, Pyrimidines, Purines and Pteredines compounds of pyridine Risdiplam bc0001