R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride

CAS No.: 125941-87-9

Chemical Name:: R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride

Synonyms: R(+)-SCH-23390;SCH 23390(HCI);SCH 23390 hydrochlor;SCH 23390 HYDROCHLORIDE;SCH 23390 hydrochloride NEW;(+)-SCH23390 Hydrochloride, 98.0+ % (HPLC);R(+)-SCH-23390 HYDROCHLORIDE SELECTIVE D 1 DOPAMINE;SCH23390 HYDROCHLORIDE; SCH-23390 HYDROCHLORIDE; R-(+)-SCH23390 HYDROCHLORIDE;R(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine;(5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride

CBNumber:: CB62131148

Molecular Formula:: C17H18ClNOHCl

Molecular Weight:: 324.24

MOL File:: 125941-87-9.mol

MSDS File:: SDS

Modify Date:: 2023/9/20 16:43:00

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R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Properties

alpha	+27～+31°(D/20℃)(c=0.5,DMF)
storage temp.	protect from light
solubility	H2O: >5mg/mL
form	solid
color	white
optical activity	[α]/D +32.1°, c = 1 in DMF(lit.)
EPA Substance Registry System	(5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride (125941-87-9)

SAFETY

Risk and Safety Statements

WGK Germany	3

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	D054	R(+)-SCH-23390 hydrochloride ≥98% (HPLC), solid	125941-87-9	5MG	₹9309.5	2022-06-14	Buy
Sigma-Aldrich(India)	D054	R(+)-SCH-23390 hydrochloride ≥98% (HPLC), solid	125941-87-9	10MG	₹19430.88	2022-06-14	Buy
Sigma-Aldrich(India)	D054	R(+)-SCH-23390 hydrochloride ≥98% (HPLC), solid	125941-87-9	25MG	₹44101.05	2022-06-14	Buy
Sigma-Aldrich(India)	D054	R(+)-SCH-23390 hydrochloride ≥98% (HPLC), solid	125941-87-9	100MG	₹137542.45	2022-06-14	Buy
Sigma-Aldrich(India)	5.05723	SCH 23390 Hydrochloride - CAS 125941-87-9 - Calbiochem	125941-87-9	10MG	₹14590	2022-06-14	Buy

Product number	Packaging	Price	Buy
D054	5MG	₹9309.5	Buy
D054	10MG	₹19430.88	Buy
D054	25MG	₹44101.05	Buy
D054	100MG	₹137542.45	Buy
5.05723	10MG	₹14590	Buy

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Chemical Properties,Uses,Production

Uses

A selective dopamine D1 receptor antagonist.

Biological Activity

Potent D 1 antagonist (K i values are ~ 0.2, 0.3, ~ 1100, ~ 800 and ~ 3000 nM at D 1 , D 5 , D 2 , D 3 and D 4 receptors respectively). Also an agonist at 5-HT 1C/2C receptors (K i = 6.3 nM) in vitro .

Biochem/physiol Actions

R(+)-SCH-23390 hydrochloride is a selective D1 dopamine receptor antagonist. It has greater binding capacity towards 5-hydroxytryptamine 2 (5-HT2) and 5-HT1C serotonin receptor subtypes in in vitro. R(+)-SCH-23390 has a half-life of about 25 minutes after administration. It is known to possess anti-stereotypic effect and cataleptogenic effect. It also has inhibitory effect on motor activity.

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Suppliers

Global( 79)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
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ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
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Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
InvivoChem	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Cayman Chemical Company	81
Shanghai EFE Biological Technology Co., Ltd.	58

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Spectrum

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride(125941-87-9)¹HNMR

125941-87-9(R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride)Related Search:

SCH772984 6-(p-Nitrophenyl)pyrrolo[2,1-d][1,5]benzothiazepine 5,5-dioxide SCH 58261 2-CHLORO-5-METHYLPHENOL P-CHLORO-BETA-METHYL-PHENETHYLAMINE HYDROCHLORIDE

2-(3-Chlorophenyl)ethylamine 4-Chlorophenethylamine 2-CHLORO-4,5-DIMETHYLPHENOL [2-(3-CHLORO-PHENYL)-ETHYL]-METHYL-AMINE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride

8-CHLORO-2,3,4,5-TETRAHYDRO-5-PHENYL-1H-3-BENZAZEPIN-7-OL-(5R) 7-CHLORO-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE 2-(4-CHLOROPHENYL)-2-PHENYLETHYLAMINE HYDROCHLORIDE N,N-BIS(2-PHENYLETHYL)AMINE HYDROCHLORIDE [2-(4-CHLORO-PHENYL)-ETHYL]-METHYL-AMINE

N,beta-Dimethylphenethylamine hydrochloride [2-(3-CHLORO-PHENYL)-ETHYL]-ETHYL-AMINE 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-OL

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R(+)-7-CHLORO-8-HYDROXY-3-METHYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROCHLORIDE SCH 23390 HYDROCHLORIDE R(+)-SCH-23390 HYDROCHLORIDE SELECTIVE D 1 DOPAMINE (5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride SCH 23390(HCI) (+)-SCH23390 Hydrochloride, 98.0+ % (HPLC) R(+)-SCH-23390 R(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine SCH23390 HYDROCHLORIDE; SCH-23390 HYDROCHLORIDE; R-(+)-SCH23390 HYDROCHLORIDE SCH 23390 hydrochloride NEW SCH 23390 hydrochlor (R)-8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride 125941-87-9 Dopamine receptor Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals