SCH 58261

CAS No.: 160098-96-4

Chemical Name:: SCH 58261

Synonyms: CS-2187;SCH-58261;SCH 58261;Butanoicacid,4-bromo-5-oxo-,ethylester;Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor;2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine

CBNumber:: CB8497477

Molecular Formula:: C18H15N7O

Molecular Weight:: 345.36

MOL File:: 160098-96-4.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

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SCH 58261 Properties

Melting point	223 °C
Density	1.54±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	DMSO: >10 mg/mL, soluble
pka	2.78±0.30(Predicted)
form	solid
color	off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

WGK Germany

HS Code

2934.99.3000

NFPA 704

	0
2		0

SCH 58261 price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	S4568	SCH 58261 ≥98% (HPLC), solid	160098-96-4	5MG	₹15923.58	2022-06-14	Buy
Sigma-Aldrich(India)	S4568	SCH 58261 ≥98% (HPLC), solid	160098-96-4	25MG	₹63748.43	2022-06-14	Buy
TCI Chemicals (India)	C3599	SCH 58261	160098-96-4	5MG	₹4100	2022-05-26	Buy
TCI Chemicals (India)	C3599	SCH 58261	160098-96-4	25MG	₹11900	2022-05-26	Buy

Product number	Packaging	Price	Buy
S4568	5MG	₹15923.58	Buy
S4568	25MG	₹63748.43	Buy
C3599	5MG	₹4100	Buy
C3599	25MG	₹11900	Buy

SCH 58261 Chemical Properties,Uses,Production

Uses

SCH 58261 is a potent and selective A2A adenosine receptor antagonist.

Biological Activity

Potent and selective A 2A adenosine receptor competitive antagonist (K i = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A 1 , A 2B and A 3 receptors, respectively.

Biochem/physiol Actions

SCH 58261 reduces the levels of TNF-α, Fas-L, Bax expression and activation of JNK-MAPK pathway. It has neuroprotective effects as it reduces demyelination of the neurons. SCH 58261 increases the concentration of secretion of dopamine and elicits locomotor sensitization, an attractive option in the possible treatment of Parkinson′s disease.

SCH 58261 Preparation Products And Raw materials

Raw materials

5-Amino-1-phenethyl-1H-pyrazole-4-carbonitrile Furan-2-carbohydrazide Cyanamide

Preparation Products

SCH 58261 Suppliers

Global( 109)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32836	60	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29824	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49739	58	Inquiry
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	China	3136	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	China	11681	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
TCI Chemicals (India) Pvt. Ltd.	58
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
career henan chemical co	58
InvivoChem	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58

SCH 58261 Spectrum

SCH 58261(160098-96-4)¹HNMR

160098-96-4(SCH 58261)Related Search:

SCH54292 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2) 2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride 6-(p-Nitrophenyl)pyrrolo[2,1-d][1,5]benzothiazepine 5,5-dioxide

SCH772984 2-PROPYL-2H-PYRAZOL-3-YLAMINE 4-METHYL-2-PROPYL-2 H-PYRAZOL-3-YLAMINE SCH 58261 1H-1,2,4-Triazole-1-carboximidamide hydrochloride

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7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine CS-2187 SCH-58261;SCH 58261 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine Butanoicacid,4-bromo-5-oxo-,ethylester Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor 160098-96-4 C18H15N7O Adenosine receptor