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1H-1,2,4-Triazole-1-carboximidamide hydrochloride

CAS No.: 19503-26-5

Chemical Name:: 1H-1,2,4-Triazole-1-carboximidamide hydrochloride

Synonyms: 1H-1,2,4-triazole-1-carboxiMidaMide hydrochloride;NOLA-010;1H-1,2,4-TRI;TIMTEC-BB SBB004089;Methotrexate (Abitrexate);1-CARBAMIDINO-1,2,4-TRIAZOLE;1,2,4-triazole-1-carboximidamide;1H-1,2,4-Triazole-1-CarboxaMidine;1-AMIDINO-1,2,4-TRIAZOLE HYDROCHLORIDE;1H-1,2,4-triazole-1-carboximidamide HCl

CBNumber:: CB1711419

Molecular Formula:: C3H6ClN5

Molecular Weight:: 147.57

MOL File:: 19503-26-5.mol

Modify Date:: 2023/11/22 14:05:49

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1H-1,2,4-Triazole-1-carboximidamide hydrochloride Properties

Melting point	215-220 °C
storage temp.	Inert atmosphere,Room Temperature
Water Solubility	Soluble in water
form	powder to crystal
color	White to Almost white
BRN	9500271
InChI	InChI=1S/C3H5N5.ClH/c4-3(5)8-2-6-1-7-8;/h1-2H,(H3,4,5);1H
InChIKey	JDDXNENZFOOLTP-UHFFFAOYSA-N
SMILES	C(N1N=CN=C1)(N)=N.Cl
CAS DataBase Reference	19503-26-5

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H317-H319-H412
Precautionary statements	P264-P280i-P301+P312a-P337+P313-P501a-P280-P301+P312+P330-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22-36-52/53-43
Safety Statements	26-36/37-61
RIDADR	2811
WGK Germany	3
HazardClass	6.1
PackingGroup	III
HS Code	29339900

1H-1,2,4-Triazole-1-carboximidamide hydrochloride price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	T3124	1,2,4-Triazole-1-carboximidamide Hydrochloride	19503-26-5	1G	₹2000	2022-05-26	Buy
TCI Chemicals (India)	T3124	1,2,4-Triazole-1-carboximidamide Hydrochloride	19503-26-5	5G	₹3800	2022-05-26	Buy
ALFA India	ALF-H60475-14	1H-1,2,4-Triazole-1-carboxamidine hydrochloride, 98%	19503-26-5	25g	₹9003	2022-05-26	Buy
ALFA India	ALF-H60475-06	1H-1,2,4-Triazole-1-carboxamidine hydrochloride, 98%	19503-26-5	5g	₹1063	2022-05-26	Buy

Product number	Packaging	Price	Buy
T3124	1G	₹2000	Buy
T3124	5G	₹3800	Buy
ALF-H60475-14	25g	₹9003	Buy
ALF-H60475-06	5g	₹1063	Buy

1H-1,2,4-Triazole-1-carboximidamide hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White crystalline

Uses

[1,2,4]Triazole-1-carboxamidine is an intermediate used in the synthesis of peramivir (P285500), a neuraminidase inhibitor developed as an antiviral agent for the treatment of influenza.

Synthesis

1H-1,2,4-Triazole-1-carboxamidine hydrochloride is prepared by the reaction of dicyandiamide and 1,2,4-Triazole. The steps are as follows:
Dissolve the compound (19.7 g, 0.29 mol) in 20 ml of tetrahydrofuran, and the temperature was raised to 70℃. A solution of dicyandiamide (20 g, 0.24 mol) was added and a solution of 4 mol / L HCl in tetrahydrofuran 27 g, 0.26 mol) at 70℃ for 2 h, the temperature was removed and cooled to room temperature. The solid was removed by filtration and 26.0 g was removed by filtration. The solvent was dried in vacuo at 45℃ to give a colorless oil which was recrystallized from methanol: dichloromethane = 2: 1 Of the mixed solution 50ml recrystallization, cooling crystallization, suction filter to get 6.2g solid, drying a total of 30.1g white powder. Yield 90.3%, purity 99,8%.
1H-1,2,4-Triazole-1-carboxamidine hydrochloride synthesis

1H-1,2,4-Triazole-1-carboximidamide hydrochloride Preparation Products And Raw materials

Raw materials

1,2,4-Triazole Ethanol Sodium chloride 1,4-Dioxane Hydrochloric acid

Cyanamide Sulfuric acid

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Preparation Products

1H-1,2,4-Triazole-1-carboximidamide hydrochloride Suppliers

Global( 217)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6913	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
Sinopharm International Guangzhou Ltd.	+86-2038033341 +86-18520036739	China	77	58	Inquiry
Jinan Jianfeng Chemical Co., Ltd	+8615562555968	China	247	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21661	55	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
TCI Chemicals (India) Pvt. Ltd.	58
Alfa Aesar	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58
Sinopharm International Guangzhou Ltd.	58
Jinan Jianfeng Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55

19503-26-5(1H-1,2,4-Triazole-1-carboximidamide hydrochloride)Related Search:

SCH 58261 FLUQUINCONAZOLE MRS 1220 1H-1,2,4-Triazole-1-carboximidamide hydrochloride CGS 15943

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SALOR-INT L120987-1EA 3-(4-CHLOROPHENYL)-1-(8-IMINO-8,9-DIHYDRO-7H-[1,2,4]TRIAZOLO[1,5-D][1,2,4]TRIAZEPIN-5-YL)-5-(TRIFLUOROMETHYL)-4,5-DIHYDRO-1H-PYRAZOL-5-OL SALOR-INT L121002-1EA 1-(7-AMINO[1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-YL)-3-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-4,5-DIHYDRO-1H-PYRAZOL-5-OL 1-(8-IMINO-8,9-DIHYDRO-7H-[1,2,4]TRIAZOLO[1,5-D][1,2,4]TRIAZEPIN-5-YL)-3-(2-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)-4,5-DIHYDRO-1H-PYRAZOL-5-OL

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1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHYDROCHLORIDE 1-CARBAMIDINO-1,2,4-TRIAZOLE 1H-1,2,4-Triazole-1-carboxamidine monohydrochloride ,98.5% 1-AMIDINO-1,2,4-TRIAZOLE HYDROCHLORIDE TIMTEC-BB SBB004089 1h-1,2,4-triazole-1-carboxamidinehydrochloride 1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHY (1H)-1,2,4-Triazole-1-carboxamidineHClpurum (1H)-1,2,4-Triazole-1-carboxamidinemonohydrochloridepurum 1-amidino-1h-1,2,4-triazole hydrochloride 1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHY DROCHLORIDE PURUM 98+% 1H-1,2,4-Triazole-1-CarboxaMidine Methotrexate (Abitrexate) 1H-1,2,4-Triazole-1-carboxaMidine Monohydrochloride ,98% [1,2,4]Triazole-1-carboxaMidine Hydrochloride 1,2,4-Triazole-1-carboximidamide Hydrochloride 1H-1,2,4-Triazole-1-carboxamidine hydrochloride≥ 98%(Titration) 1-Carbamimidoyl-1,2,4-triazole Hydrochloride 1H-1,2,4-Triazole-1-carboximidamide, hydrochloride (1:1) 1-Amidino-1,2,4-triazole monohydrochloride NOLA-010 1H-1,2,4-TRI TIANFU-CHEM - 1H-1,2,4-TRIAZOLE-1-CARBOXAMIDINE MONOHYDROCHLORIDE 1,2,4-triazole-1-carboximidamide 1H-1,2,4-triazole-1-carboxiMidaMide hydrochloride 1H-1,2, 4-triazol-1-methylamidine monohydrochloride 1H-1,2,4-triazole-1-carboximidamide HCl 19503-26-5 C3H6ClN5 C3H5N5HCl C3H5N5ClH Guanidine Protection/Guanidinylation Peptide Synthesis Specialty Synthesis