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5-Chlorouracil

5-Chlorouracil Structure
CAS No.
1820-81-1
Chemical Name:
5-Chlorouracil
Synonyms
5-CHLOROPYRIMIDINE-2,4(1H,3H)-DIONE;Fluorouracil EP Impurity E;5-Chloro-1H-pyrimidine-2,4-dione;NSC 28172;5-chloro-uraci;5-CHLOROURACIL;Uracil,5-chloro-;5-CHLORO-5-URACIL;5-Chlorouracil,99%;5-Chlorouracil,98%
CBNumber:
CB6216858
Molecular Formula:
C4H3ClN2O2
Molecular Weight:
146.53
MOL File:
1820-81-1.mol
MSDS File:
SDS
Modify Date:
2023/8/22 13:52:55

5-Chlorouracil Properties

Melting point >300 °C (lit.)
Density 1.6838 (rough estimate)
refractive index 1.6550 (estimate)
storage temp. 2-8°C
solubility 1 M NH4OH: soluble50mg/mL
pka 6.77±0.10(Predicted)
form Solid
color White to Off-White
Water Solubility 2.501g/L(25 ºC)
BRN 127173
InChIKey ZFTBZKVVGZNMJR-UHFFFAOYSA-N
CAS DataBase Reference 1820-81-1(CAS DataBase Reference)
EPA Substance Registry System 5-Chlorouracil (1820-81-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H341
Precautionary statements  P201-P202-P264-P270-P280-P301+P310
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
RTECS  YQ9410000
HS Code  29335995
NFPA 704
1
0 0

5-Chlorouracil price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 224588 5-Chlorouracil ReagentPlus?, 99% 1820-81-1 5G ₹4492.38 2022-06-14 Buy
Sigma-Aldrich(India) PHR2867 Fluorouracil Related Compound E certified reference material, pharmaceutical secondary standard 1820-81-1 50MG ₹56030.2 2022-06-14 Buy
Sigma-Aldrich(India) 224588 5-Chlorouracil ReagentPlus?, 99% 1820-81-1 25G ₹13542.08 2022-06-14 Buy
ALFA India ALF-A11084-22 5-Chlorouracil, 98% 1820-81-1 100g ₹10057 2022-05-26 Buy
TCI Chemicals (India) C0969 5-Chlorouracil 1820-81-1 5G ₹2600 2022-05-26 Buy
Product number Packaging Price Buy
224588 5G ₹4492.38 Buy
PHR2867 50MG ₹56030.2 Buy
224588 25G ₹13542.08 Buy
ALF-A11084-22 100g ₹10057 Buy
C0969 5G ₹2600 Buy

5-Chlorouracil Chemical Properties,Uses,Production

Chemical Properties

white to light beige crystalline powder

Uses

5-Chlorouracil can be used for the experimental and clinical treatment of neoplastic and viral diseases.

Definition

ChEBI: An organochlorine compound consisting of uracil having an chloro substituent at the 5-position.

General Description

The shape resonance spectra of 5-chlorouracil, obtained from fixed-nuclei elastic scattering calculations by the Schwinger multichannel method with pseudopotentials, was studied.

Purification Methods

It recrystallises from hot H2O (4g/500mL) using charcoal. [McOmie et al. J Chem Soc 3478 1955, West & Barrett J Am Chem Soc 76 3146 1954, Beilstein 24 III/IV 1231.]

5-Chlorouracil Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 447)Suppliers
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NSR Laboratories Pvt. Ltd. +91-9866989891 +91-9000457345 Hyderabad, India 196 58 Inquiry
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Spectrochem Private Limited 08048372608Ext 246 Maharashtra, India 1056 58 Inquiry
Opulent Pharma 08068441147Ext 981 Gujarat, India 810 58 Inquiry
TIMTEC-BB SBB004103 2,4(1H,3H)-Pyrimidinedione,5-chloro- 2,4-Pyrimidinediol,5-chloro- 3h)-pyrimidinedione,5-chloro-4(1h 5-Chloro-1,2,3,4-tetrahydropyrimidine-2,4-dione 5-Chloropyrimidine-2,4-diol 5-Chlorouracil,99% Fluorouracil Related CoMpound E 5-Chlorouracil ReagentPlus(R), 99% Fluorouracil Related Compound E (25 mg) (5-Chloropyrimidine-2,4(1H,3H)-dione) 5-Chlorouracil Vetec(TM) reagent grade, 98% 5-Chlor-2,4-dihydroxypyrimidin 5-Chloro-2,4-pyrimidinedione 5-chloro-uraci Uracil,5-chloro- 5-CHLORO-2,4-DIHYDROXYPYRIMIDINE 5-CHLORO-5-URACIL 5-CHLOROURACIL 5-CHLOROURACIL,5-CHLORO-2,4-DIHYDROXYPYRIMIDINE 2,4(1H,3H)-Pyrimidinedione, 5-chloro- (9CI) 5-Chloro-2,4(1H,3H)-pyrimidinedione NSC 28172 5-CHLOROURACIL CRYSTALLINE 5-Chlorouracil,98% Fluorouracil Impurity 5(Fluorouracil EP Impurity E) Fluorouracil BP Impurity E 5-Chlorouracil > 5-Chlorouracil USP/EP/BP 5-Chlorouracil (Fluorouracil Impurity) 4(1H,3H)-Pyrimidinedione,5-chloro- Fluorouracil EP Impurity E (5-Chlorouracil) 5-ChlorouracilQ: What is 5-Chlorouracil Q: What is the CAS Number of 5-Chlorouracil Q: What is the storage condition of 5-Chlorouracil Q: What are the applications of 5-Chlorouracil Fluorouracil Related Compound E (5-Chloropyrimidine-2,4(1H,3H)-dione) (1279054) 5-Chloro-1H-pyrimidine-2,4-dione 5-CHLOROPYRIMIDINE-2,4(1H,3H)-DIONE Fluorouracil EP Impurity E Fluorouracil USP Related Compound E 5-chloro-2,4-dioxopyrimidine Fluorouracil Related Compound E (5-Chloropyrimidine-2,4(1H,3H)-dione) Fluorouracil EP Impurity E (Fluorouracil USP Related Compound E) 1820-81-1 156-2-19 C4H3ClN2O2 Building Blocks Pyrimidines Heterocyclic Building Blocks Halogenated Heterocycles Pyrimidine series Heterocyclic Compounds Biochemistry Nucleobases and their analogs Nucleosides, Nucleotides & Related Reagents Nucleic acids Bases & Related Reagents Heterocycles Nucleotides PYRIMIDINE Pyridines, Pyrimidines, Purines and Pteredines