(+)-FANGCHINOLINE
- CAS No.
- 436-77-1
- Chemical Name:
- (+)-FANGCHINOLINE
- Synonyms
- Hanfangchin B（Fangchinoline）;(+)-limacine;Tetrandrine B;Hanfangichin B;FANGCHINO-LINE;(+)-FANGCHINOLINE;FANGCHINOLINE (RG);7-o-demethyltetrandrine;12-O-MethylatherosperMoline;(+)-FANGCHINOLINE USP/EP/BP
- CBNumber:
- CB6221346
- Molecular Formula:
- C37H40N2O6
- Molecular Weight:
- 608.72
- MOL File:
- 436-77-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/26 15:15:06
| Melting point | 240～242℃ |
|---|---|
| Boiling point | 709.7±60.0 °C(Predicted) |
| Density | 1.204±0.06 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| solubility | Soluble in chloroform and methanol; |
| pka | 9.38±0.20(Predicted) |
| form | powder to crystal |
| color | White to Orange to Green |
| Water Solubility | slightly soluble in water |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| HS Code | 2939.79.0000 | |||||||||
| NFPA 704 |
|
(+)-FANGCHINOLINE price More Price(2)
(+)-FANGCHINOLINE Chemical Properties,Uses,Production
Description
A bisbenzylisoquino!ine alkaloid obtained from Limacia cuspidata (Miers.) Hook. f. et Thorn., the base crystallizes from Me2CO in the form of long, colourless needles. It is strongly laevorotatory with [α]D - 2120 (CHCI3) and has been shown to be the optical antipode of fanchinoline (q.v.).
Uses
(+)-Fangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
Definition
ChEBI: A bisbenzylisoquinoline alkaloid that is (1beta)- berbaman which has been substituted by methyl groups at the 2 and 2' positions, by methoxy groups at the 6, 6', and 12 positions, and by a hydroxy group at position 7. Isolated from S ephania tetrandra, it has been found to possess neuroprotective and anti-tumour activity.
References
Tomita, Furukawa., Tetrahedron Lett., 4293 (1966)
(+)-FANGCHINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | China | 2303 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12456 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16208 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860 +86-18080483897 | China | 3424 | 58 | Inquiry |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
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