trans-Dichlorodiamineplatinum(II)
![trans-Dichlorodiamineplatinum(II) Structure](CAS/GIF/14913-33-8.gif)
- CAS No.
- 14913-33-8
- Chemical Name:
- trans-Dichlorodiamineplatinum(II)
- Synonyms
- CPDC;CIS-DDP;PLATINEX;PLATINOL;NEOPLATIN;PLATAMINE;BRIPLATIN;CISPLATYL;CISMAPLAT;nsc131558
- CBNumber:
- CB6236182
- Molecular Formula:
- Cl2H4N2Pt
- Molecular Weight:
- 298.03
- MOL File:
- 14913-33-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/15 10:42:46
Melting point | 340 °C (dec.)(lit.) |
---|---|
storage temp. | 2-8°C |
solubility | DMSO (Sparingly) |
form | crystalline |
color | yellow |
Water Solubility | Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water. |
Exposure limits |
ACGIH: TWA 0.002 mg/m3 NIOSH: IDLH 4 mg/m3; TWA 0.002 mg/m3 |
EPA Substance Registry System | Platinum, diamminedichloro-, (SP-4-1)- (14913-33-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS05,GHS08 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H317-H318-H334 | |||||||||
Precautionary statements | P280-P302+P352-P305+P351+P338+P310 | |||||||||
Hazard Codes | T,Xn | |||||||||
Risk Statements | 45-25-41-68-42/43-40-23/24/25 | |||||||||
Safety Statements | 53-26-39-45-36/37-24-23 | |||||||||
RIDADR | UN 3288 6.1/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TP2455000 | |||||||||
F | 10-21 | |||||||||
HazardClass | 6.1(a) | |||||||||
PackingGroup | II | |||||||||
HS Code | 28439000 | |||||||||
Toxicity | mouse,LD50,intraperitoneal,27mg/kg (27mg/kg),Chemico-Biological Interactions. Vol. 5, Pg. 415, 1972. | |||||||||
NFPA 704 |
|
trans-Dichlorodiamineplatinum(II) price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P1525 | trans-Platinum(II)diammine dichloride | 14913-33-8 | 250MG | ₹7980.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P1525 | trans-Platinum(II)diammine dichloride | 14913-33-8 | 1G | ₹21978 | 2022-06-14 | Buy |
ALFA India | ALF-010472-06 | trans-Diamminedichloroplatinum(II), Pt 64.5% min | 14913-33-8 | 5g | ₹105930 | 2022-05-26 | Buy |
ALFA India | ALF-010472-03 | trans-Diamminedichloroplatinum(II), Pt 64.5% min | 14913-33-8 | 1g | ₹11247 | 2022-05-26 | Buy |
trans-Dichlorodiamineplatinum(II) Chemical Properties,Uses,Production
Chemical Properties
Yellow Powder or Crystal
Uses
Transplatin is the trans stereoisomer impurity of trans-Dichlorodiamineplatinum(II), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
Definition
ChEBI: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.
Safety Profile
Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. See also PLATINUM COMPOUNDS. When heated to decomposition it emits toxic fumes of NOx and Cl-.
trans-Dichlorodiamineplatinum(II) Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
GLP Pharma Standards | +91 9866074638 | Hyderabad, India | 1644 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21677 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
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