ChemicalBook > Product Catalog >Biochemical Engineering >Plant extracts >SINOMENINE HYDROCHLORIDE

SINOMENINE HYDROCHLORIDE

SINOMENINE HYDROCHLORIDE Structure
CAS No.
6080-33-7
Chemical Name:
SINOMENINE HYDROCHLORIDE
Synonyms
Sinomenin HCl;SINOMENINE HCL;Cucoline hydrochloride;Kukoline hydrochloride;Sinomenine Hydrocloride;SINOMENINE HYDROCHLORIDE;Tuduranine Hydrochloride;Sinomenine HCl Dihydrate;Sabianine A hydrochloride;Sinomenine Hydrochloride >
CBNumber:
CB6245173
Molecular Formula:
C19H24ClNO4
Molecular Weight:
365.85
MOL File:
6080-33-7.mol
Modify Date:
2024/5/11 20:10:50

SINOMENINE HYDROCHLORIDE Properties

Melting point 231.0 to 235.0 °C
storage temp. Inert atmosphere,2-8°C
solubility H2O: soluble20mg/mL, clear
form powder
color white to beige
optical activity [α]/D -70 to -90°, c = 1 in H2O
Water Solubility Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335-H351
Precautionary statements  P201-P280-P301+P312+P330-P302+P352+P312-P304+P340+P312-P308+P313
Safety Statements  24/25
WGK Germany  3
RTECS  QD2163000
HS Code  29334900
NFPA 704
0
3 0

SINOMENINE HYDROCHLORIDE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML1002 Sinomenine hydrochloride ≥98% (HPLC) 6080-33-7 50MG ₹11528.63 2022-06-14 Buy
TCI Chemicals (India) S0926 Sinomenine Hydrochloride 6080-33-7 1G ₹8100 2022-05-26 Buy
TCI Chemicals (India) S0926 Sinomenine Hydrochloride 6080-33-7 5G ₹25900 2022-05-26 Buy
Product number Packaging Price Buy
SML1002 50MG ₹11528.63 Buy
S0926 1G ₹8100 Buy
S0926 5G ₹25900 Buy

SINOMENINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Sinomenine is a natural plant alkaloid commonly used to alleviate inflammation associated with rheumatoid arthritis. It activates histamine release, reduces joint stiffness and pain, and alters cytokine generation without producing gastrointestinal adverse events. Sinomenine also impairs signaling through NF-κB, resulting in immunosuppression as well as reduced inflammation and pain. It enhances the bioavailability of some compounds, at least in part through an inhibition of drug export by transporters like P-glycoprotein.

Chemical Properties

White Solid

Uses

Sinomenine is an optical isomer of Methoxythebainone. Sinomenine was extracted from root of Sinomenium acutum. Sinomenine has anti-inflammatory and analgesic effect.

Purification Methods

Crystallise the salt from water (1g/1.5mL) or EtOH. The free base [115-53-7] M 329.4, has m 161o (from EtOH) (and again at 182o) after crystallisation from *C6H6, and [] D 20 -78.9o (c 1, EtOH). The picrate has m 159-162o(dec) (from H2O). [Beilstein 21 II 470, 21 III/IV 6670.]

SINOMENINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 211)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Hebei Zhuanglai Chemical Trading Co.,Ltd +8613343047651 China 3002 58 Inquiry
Hebei Shengyang Water Conservancy Engineering Co., Ltd. +8615373025980 China 857 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry

SINOMENINE HYDROCHLORIDE Spectrum

(9a,13a,14a)-4-Hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochloride SINOMENINE HYDROCHLORIDE SINOMENINE HCL (9α,13α,14α)- 7,8-Didehydro-4- hydroxy-3,7-diMet 7,8-Didehydro-4-hydroxy-3,7-diMethoxy-17-Methyl- 9α,13α,14α-Morphinan-6-one Hydrochloride Tuduranine Hydrochloride hydroxy-dimethoxy-methyl-BLAH-azatetracyclo[BLAH]hexadeca-BLAH,BLAH,BLAH,BLAH-tetraenone Sinomenine Hydrocloride Cucoline hydrochloride Sinomenine hydrochloride (Cucoline hydrochloride) Sinomenine Hydrochloride > Kukoline hydrochloride Sabianine A hydrochloride TIANFU-CHEM CAS:6080-33-7 SINOMENINE HYDROCHLORIDE 9α,13α,14α-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, hydrochloride Sinomenine hydrochloride (Cucoline) Sinomenine HCl Dihydrate Sinomenine hydrochloride (6CI, 7CI) Sinomenin HCl 98% Sinomenine Hydrochloride Powder Sinomenine Hydrochloride, ≥ 98.0% 6080-33-7 C19H23NO4HCl Alkaloids Inhibitors pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract chemical reagent Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals APIs