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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Cell Cycle >Aurora Kinase Inhibitors >MK-5108 (VX-689)

MK-5108 (VX-689)

MK-5108 (VX-689) Structure
CAS No.
1010085-13-8
Chemical Name:
MK-5108 (VX-689)
Synonyms
MK-5108;VX-689;CS-545;MK-5198;MK-5108(VX-689);MK-5108 (VX-689) USP/EP/BP;MK-5108 VX-689 Aurora Kinase Inhibitor;MK 5108; VX-689; VX 689; MK5108; VX689;trans-4-(3-Chloro-2-fluorophenoxy)-1-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]cyclohexanecarboxylic acid;4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid
CBNumber:
CB62570376
Molecular Formula:
C22H21ClFN3O3S
Molecular Weight:
461.94
MOL File:
1010085-13-8.mol
Modify Date:
2024/11/11 17:44:06
Request For Quotation

MK-5108 (VX-689) Properties

Boiling point 637.6±65.0 °C(Predicted)
Density 1.429
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility ≥23.1 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form solid
pka 4.41±0.44(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

MK-5108 (VX-689) Chemical Properties,Uses,Production

Uses

MK-5108 is a highly selective Aurora-A kinase inhibitor that shows antitumor activity alone and in combination with Docetaxel (D494420).

MK-5108 (VX-689) Preparation Products And Raw materials

Raw materials

Preparation Products

MK-5108 (VX-689) Suppliers

Global( 116)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32080 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30241 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22883 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10473 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6391 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3135 58 Inquiry
TargetMol Chemicals Inc. United States 38470 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8467 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43340 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57505 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Nantong HI-FUTURE Biology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
LEAPCHEM CO., LTD. 58
Aladdin Scientific 58

MK-5108 (VX-689) Spectrum

MK-5108 (VX-689)(1010085-13-8)1HNMR

1010085-13-8(MK-5108 (VX-689))Related Search:

Bortezomib Alisertib (MLN8237) Aurora A Inhibitor I Hesperadin MLN8054
Barasertib (AZD1152-HQPA)
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trans-4-(3-Chloro-2-fluorophenoxy)-1-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]cyclohexanecarboxylic acid MK-5108(VX-689) (1r,4r)-4-(3-chloro-2-fluorophenoxy)-1-((6-(thiazol-2-ylaMino)pyridin-2-yl)Methyl)cyclohexanecarboxylic acid MK-5198 MK 5108; VX-689; VX 689; MK5108; VX689 CS-545 Cyclohexanecarboxylic acid, 4-(3-chloro-2-fluorophenoxy)-1-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-, trans- MK-5108 (VX-689) USP/EP/BP MK-5108 VX-689 MK-5108 VX-689 Aurora Kinase Inhibitor 4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid trans-4-(3-Chloro-2-fluorophenoxy)-1-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)cyclohexane-1-carboxylic acid 1010085-13-8 Inhibitors Inhibitor