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4-methoxy-3-methylaniline

4-methoxy-3-methylaniline Structure
CAS No.
136-90-3
Chemical Name:
4-methoxy-3-methylaniline
Synonyms
3-methyl-p-anisidine;4-AMINO-2-METHYLANISOLE;3-Methyl-4-methoxyaniline;4-METHOXY-3-METHYLANILINE;3-Methyl-4-methoxybenzenamine;4-methoxy-3-methylbenzenamine;BenzenaMine, 4-Methoxy-3-Methyl-;4-AMINO-24-AMINO-2-METHYLANISOLE-METHYLANISOLE;4-AMino-2-Methylanisole[4-Methoxy-3-Methylaniline]
CBNumber:
CB6266868
Molecular Formula:
C8H11NO
Molecular Weight:
137.18
MOL File:
136-90-3.mol
MSDS File:
SDS
Modify Date:
2024/7/11 19:21:31

4-methoxy-3-methylaniline Properties

Melting point 57-60℃
Boiling point 252.03°C (rough estimate)
Density 1.0630 (rough estimate)
refractive index 1.5360 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka 5.32±0.10(Predicted)
form Solid
color Dark Red to Black

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
HS Code  2922290090

4-methoxy-3-methylaniline price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 724661 4-Methoxy-3-methylaniline 98% 136-90-3 1G ₹9785.8 2022-06-14 Buy
Product number Packaging Price Buy
724661 1G ₹9785.8 Buy

4-methoxy-3-methylaniline Chemical Properties,Uses,Production

Uses

4-Methoxy-3-methylaniline is used in preparation of triamine pyrimidine derivatives as antitumor agents.

Synthesis

The synthesis of 4-methoxy-3-methylaniline is as follows:
4-Methoxy-3-methyl-phenylamine10% Palladium on carbon (10% Pd/C) (1.5 g) was added to a solution of 1 -methoxy-2- methyl-4-nitrobenzene (9.5 g, 57 mmol) in methanol (100 ml_). The mixture was stirred under a hydrogen atmosphere (1 atm.) at room temperature for 16 h. The mixture was filtered through a pad of CELITE and the filtrate was evaporated in vacuo to yield 4- methoxy-3-methylphenylamine (8.0 g, 57 mmol, 100%).
synthesis of 4-methoxy-3-methylaniline.png

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4-AMino-2-Methylanisole[4-Methoxy-3-Methylaniline] 3-Methyl-4-methoxybenzenamine 4-AMINO-2-METHYLANISOLE 4-METHOXY-3-METHYLANILINE 3-Methyl-4-methoxyaniline 4-methoxy-3-methylbenzenamine BenzenaMine, 4-Methoxy-3-Methyl- 4-AMINO-24-AMINO-2-METHYLANISOLE-METHYLANISOLE 3-methyl-p-anisidine 136-90-3