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ETHYL LOFLAZEPATE

ETHYL LOFLAZEPATE Structure
CAS No.
29177-84-2
Chemical Name:
ETHYL LOFLAZEPATE
Synonyms
Victan;Meilax;cm6912;CM 6912;arboxylate;Ethyl Loazepate;ethylfluclozepate;ETHYL LOFLAZEPATE;Ethyl lofrazepate;Ethyl fluclozepate
CBNumber:
CB6269238
Molecular Formula:
C18H14ClFN2O3
Molecular Weight:
360.77
MOL File:
29177-84-2.mol
Modify Date:
2023/5/4 17:34:37
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ETHYL LOFLAZEPATE Properties

Melting point 193-194°
Boiling point 507.7±50.0 °C(Predicted)
Density 1.3609 (estimate)
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml; Methanol: 1 mg/ml
form A crystalline solid
pka 10.56±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H336
Precautionary statements  P261-P271-P304+P340-P312-P403+P233-P405-P501

ETHYL LOFLAZEPATE Chemical Properties,Uses,Production

Originator

Victan,Clin Midy,France,1982

Uses

A new benzodiazepine derivative as a new anti-anxiety drug. Ethyl Loflazepate and its metabolite were compared with those of Diazepam (D416855), Nitrazepam (N490140) and Lorazepam (L469850). The anticonflict effect of Ethyl Loflazepate was slightly more potent than that of Diazepam and much more potent than that of Lorazepam. Controlled substance.

Therapeutic Function

Tranquilizer

ETHYL LOFLAZEPATE Preparation Products And Raw materials

Raw materials

2-Amino-5-chloro-2'-fluorobenzophenone

Preparation Products

29177-84-2(ETHYL LOFLAZEPATE)Related Search:

CLENBUTEROL D9 Clenbuterol hydrochloride Clenpenterol N-(DIPHENYLMETHYLENE)GLYCINE METHYL ESTER 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid
3-Amino-L-alanine hydrochloride N-desalkylflurazepam ([1-PHENYL-METH-(E)-YLIDENE]-AMINO)-ACETIC ACID ETHYL ESTER ETHYL LOFLAZEPATE N-(A-METHYLBENZYLIDENE)ISOPROPYLAMINE
3-[(4-chlorophenyl)amino]propanoic acid Ethyl N-(diphenylmethylene)glycinate Ethyl (+/-)-BMAA HYDROCHLORIDE (SYNTHETIC) SYN THETIC PREPARATION
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ethylfluclozepate Loflazepic acid, ethyl ester loflazepicacid,ethylester Meilax Victan 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-, ethyl ester (8CI) 7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepine-3-carboxylic acid ethyl ester 7-Chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepine-3-carboxylic acid ethyl ester Ethyl lofrazepate Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydr ETHYL LOFLAZEPATE 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-, ethyl ester 1h-1,4-benzodiazepine-3-carboxylicacid,7-chloro-5-(2-fluorophenyl)-2,3-dihydr arboxylate CM 6912 cm6912 Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylate Ethyl 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepine-3-carboxylate Ethyl fluclozepate ethyl7-chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-1h-1,4-benzodiazepine-3-c CUCHJCMWNFEYOM-UHFFFAOYSA-N 7-chloro-3-ethoxycarbonyl-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepine Ethyl Loazepate Ethyl Loflazepate (1.0mg/ml in Acetonitrile) 29177-84-2 C18H14ClFN2O3 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals