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N-desalkylflurazepam

CAS No.: 2886-65-9

Chemical Name:: N-desalkylflurazepam

Synonyms: DESALKYLFLURAZEPAM;NORFLUDIAZEPAM;N-desallkylflurazepam;FlurazepaM Related CoMpound F;cm7116;ro5-3367;sch17514;MMK1 TFA;RO 5-3367;nor-Flurazepam

CBNumber:: CB4316060

Molecular Formula:: C15H10ClFN2O

Molecular Weight:: 288.7

MOL File:: 2886-65-9.mol

Modify Date:: 2024/7/2 8:55:08

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N-desalkylflurazepam Properties

Melting point	204-206°C
Boiling point	454.0±45.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
Flash point	9℃
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	A neat solid
pka	11.55±0.70(Predicted)
color	White to off-white
InChI	InChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
InChIKey	UVCOILFBWYKHHB-UHFFFAOYSA-N
SMILES	N1C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=NCC1=O
CAS DataBase Reference	2886-65-9(CAS DataBase Reference)
NIST Chemistry Reference	Norfludiazepam(2886-65-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H336

Precautionary statements

P261-P271-P304+P340+P312-P403+P233-P405-P501

Hazard Codes

F,T

Risk Statements

11-23/24/25-39/23/24/25

Safety Statements

22-24/25-45-36/37-16-7

RIDADR

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany

RTECS

DF2370100

HS Code

2933997500

NFPA 704

	0
2		0

N-desalkylflurazepam price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	D-915	Desalkylflurazepam solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?	2886-65-9	1ML	₹4655	2022-06-14	Buy

Product number	Packaging	Price	Buy
D-915	1ML	₹4655	Buy

N-desalkylflurazepam Chemical Properties,Uses,Production

Description

Desalkylflurazepam (Item No. 18484) is an analytical reference material that is structurally categorized as a benzodiazepine. It is an active metabolite of several benzodiazepines, including flurazepam , flutoprazepam, fludiazepam, midazolam, and quazepam. Desalkylflurazepam inhibits L-type voltage-gated calcium channels (Ca_v; IC₅₀s = 55 and 37 μM for Ca_v1.2 and 1.3, respectively) by positively modulating GABA_A receptors. It can be detected in urine, serum, and meconium by LC-MS/MS. This product is intended for research and forensic applications.

Chemical Properties

Light Yellow Solid

Uses

The major human metabolite of flurazepam. This is a controlled drug precursor therefore a liscence may be required for purchase

General Description

N-Desalkylflurazepam (also known as norflurazepam, 2886-65-9) is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward.

Mode of action

N-Desalkylflurazepam is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward.

N-desalkylflurazepam Preparation Products And Raw materials

Raw materials

7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethyl-ene-2H-1,4-benzodiazepine 2-bromo-4'-chloro-2'-(o-fluorobenzoyl)acetanilide 2-chloro-N-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide BOC-Glycine

Preparation Products

Flualprazolam 2-Amino-5-chloro-2'-fluorobenzophenone 4-Imidazolidinone, 1,1'-methylenebis[3-[4-chloro-2-(o-fluorobenzoyl)phenyl]- (7CI,8CI) Midazolam [7-CHLORO-5-(2-FLUORO-PHENYL)-3H-BENZO[E][1,4]DIAZEPIN-2-YL]-METHYL-AMINE

N-desalkylflurazepam Suppliers

Global( 168)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	China	12446	58	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	China	18642	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21667	55	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9343	55	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29888	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49392	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

N-desalkylflurazepam Spectrum

N-desalkylflurazepam(2886-65-9)¹HNMR

2886-65-9(N-desalkylflurazepam)Related Search:

CHLOROPHENYLSILANE 97 Hydrochlorothiazide tert-Butylchlorodiphenylsilane Epichlorohydrin PHENYL VALERATE

Chlorodimethylphenylsilane DBU Triphenylmethyl Chloride Phenylhydrazine Dihydromyrcenol

7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one FLURAZEPAM DIHYDROCHLORIDE Doxefazepam Elfazepam Chloroacetic acid

Proflazepam Difluorochloromethane Fludiazepam

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Dealkylflurazepam Descarbethoxyloflazepate Flurazepam M (des-alkyl) Flurazepam M (N-1-des-alkyl) Flurazepam, des-alkyl N-1-desalkyl-flurazepam N-Desalkyl-2-oxoquazepam N-Desalkylflurazepam N-Desalkylflutoprazepam norflutoprazepam RO 5-3367 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-2h-4-benzodiazepin-2-one 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-fluorophenyl)-1,3-dihydro- 7-chloro-5-(o-fluorophenyl)-1,3-dihydro-2h-4-benzodiazepin-2-one ro5-3367 sch17514 7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE 7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-1,4-BENZODIAZEPIN-2-ONE 7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE 5-(2-FLUOROPHENYL)-7-CHLORO-1,4-BENZODIAZEPIN-2-ONE cm7116 DESALKYLFLURAZEPAM,100/MLINMETHANOL nor-Flurazepam Flurazepam Related Compound F (50 mg) (7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one) 7-Chloro-5-(2-fluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one 7-chloro-5-(2-fluorophenyl)- 1,4-Benzodiazepin-2-one desalkylflurazepam Solution, 100ppm Desalkylflurazepam solution 7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDROXY-4-BENZODIAZEPIN-2-ONE 5-(2-Fluorophenyl)-1,3-dihydro-7-chloro-2H-1,4-benzodiazepin-2-one DESALKYLFLURAZEPAM,1.0MG/MLINMETHANOL 7-CHLORO-5-(2-FLUOROPHENYL)-1,3- DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE 98.0% MIN 2H-1,4-BENZODIAZEIN-2-ONE-7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDRO 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one 5-(2-Fluorophenyl)-1,3-dihydro-7-chloro-2H-1,4-benzodiazepin-2-oneNorfludiazepam 5-(2-Fluorophenyl)-7-chloro-1,3-dihydro-3H-1,4-benzodiazepin-2-one Flurazepam Related Compound F Solution, 100ppm Midazolam Impurity F Desalkylflurazepam (CRM) Midazolam Impurity 6(Midazolam EP Impurity F) Midazolam ImpurityⅠ:7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Flurazepam Hydrochloride ImpurityⅠ：7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one nor-Flurazepam (1.0 mg/mL in Methanol) Flurazepam Related Compound F(Secondary Standards traceble to USP) TIANFU CHEM 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Flurazepam Hydrochloride ImpurityⅠ：7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Midazolam ImpurityⅠ:7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Flurazepam Related Compound F (7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one) (1285603) 7-Chloro-5-(2-fluoropheny)-1,3-dihydro-2H-1,4-benzodiazepin-2-one NORFLUDIAZEPAM DESALKYLFLURAZEPAM FlurazepaM Related CoMpound F N-desallkylflurazepam Flurazepam USP Related Compound F N-Desalkylflurazepam, Norflurazepam Flurazepam-N-desalkyl