N-desalkylflurazepam
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N-desalkylflurazepam 속성
- 녹는점
- 204-206°C
- 끓는 점
- 454.0±45.0 °C(Predicted)
- 밀도
- 1.39±0.1 g/cm3(Predicted)
- 인화점
- 9℃
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- A neat solid
- 산도 계수 (pKa)
- 11.55±0.70(Predicted)
- 색상
- White to off-white
- InChI
- InChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
- InChIKey
- UVCOILFBWYKHHB-UHFFFAOYSA-N
- SMILES
- N1C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=NCC1=O
- CAS 데이터베이스
- 2886-65-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,T | ||
---|---|---|---|
위험 카페고리 넘버 | 11-23/24/25-39/23/24/25 | ||
안전지침서 | 22-24/25-45-36/37-16-7 | ||
유엔번호(UN No.) | UN1230 - class 3 - PG 2 - Methanol, solution | ||
WGK 독일 | 2 | ||
RTECS 번호 | DF2370100 | ||
HS 번호 | 2933997500 |
N-desalkylflurazepam C화학적 특성, 용도, 생산
개요
Desalkylflurazepam (Item No. 18484) is an analytical reference material that is structurally categorized as a benzodiazepine. It is an active metabolite of several benzodiazepines, including flurazepam , flutoprazepam, fludiazepam, midazolam, and quazepam. Desalkylflurazepam inhibits L-type voltage-gated calcium channels (Cav; IC50s = 55 and 37 μM for Cav1.2 and 1.3, respectively) by positively modulating GABAA receptors. It can be detected in urine, serum, and meconium by LC-MS/MS. This product is intended for research and forensic applications.화학적 성질
Light Yellow Solid용도
The major human metabolite of flurazepam. This is a controlled drug precursor therefore a liscence may be required for purchase일반 설명
N-Desalkylflurazepam (also known as norflurazepam, 2886-65-9) is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward.Mode of action
N-Desalkylflurazepam is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward.N-desalkylflurazepam 준비 용품 및 원자재
원자재
7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethyl-ene-2H-1,4-benzodiazepine
2-브로모-4'-클로로-2'-(o-플루오로벤조일)아세트아닐리드
2-클로로-N-[4-클로로-2-(2-플루오로벤조일)페닐]아세트아미드
BOC-Glycine
준비 용품
N-desalkylflurazepam 관련 검색:
히드로클로로티아지드 부틸디페닐클로로실란 에피클로로하이드린 1,8-디아자비사이클로[5.4.0]운덴센-7 트리틸클로라이드 페닐히드라진 디하이드로미르세놀 클로로아세트산 클로로디플루오르메탄
CHLOROPHENYLSILANE 97
PHENYL VALERATE
Chlorodimethylphenylsilane
7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
FLURAZEPAM DIHYDROCHLORIDE
Doxefazepam
Proflazepam
Elfazepam
FLURAZEPAM