Glucagon
![Glucagon Structure](CAS/GIF/16941-32-5.gif)
- CAS No.
- 16941-32-5
- Chemical Name:
- Glucagon
- Synonyms
- Glucaton;Glucagon;GlucaGen;Glucagone;Glucagonum;GLUCAGON 37;GlucagonTFA;Glucagon HCl;Glukagon TFA;Glucagon 1-29
- CBNumber:
- CB6299499
- Molecular Formula:
- C153H225N43O49S
- Molecular Weight:
- 3482.75
- MOL File:
- 16941-32-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/10 15:15:42
Density | 1.53±0.1 g/cm3(Predicted) |
---|---|
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | Practically insoluble in water and in most organic solvents. It is soluble in dilute mineral acids and in dilute solutions of alkali hydroxides. |
form | powder |
color | White to off-white |
Water Solubility | Soluble to 1 mg/ml in water |
InChIKey | MASNOZXLGMXCHN-SXVMFYJYNA-N |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS08,GHS07 |
---|---|
Signal word | Danger |
Hazard statements | H317-H332-H334 |
Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501-P261-P271-P304+P340-P312 |
WGK Germany | 3 |
F | 3-10-21 |
HS Code | 2937190000 |
Glucagon price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | G2044 | Glucagon synthetic, powder, suitable for cell culture | 16941-32-5 | 1MG | ₹11907.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | G2044 | Glucagon synthetic, powder, suitable for cell culture | 16941-32-5 | 5MG | ₹32085.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | G2044 | Glucagon synthetic, powder, suitable for cell culture | 16941-32-5 | 25MG | ₹116531.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | G1774 | Glucagon ≥95% (HPLC), powder, synthetic | 16941-32-5 | 0.1MG | ₹21000.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | G1774 | Glucagon ≥95% (HPLC), powder, synthetic | 16941-32-5 | 1MG | ₹106117.48 | 2022-06-14 | Buy |
Glucagon Chemical Properties,Uses,Production
Chemical Properties
White or almost white powder
Uses
Glucagon is an Amino Acid sequence.
Definition
Produced by the α cells of the islands of Langerhans and also by the gastric mucosa. It is opposite in effect to insulin. It appears to be a straight-chain polypeptide with a molecular weight of approximately 3500. Small amounts have been detected in comm
Biological Functions
Glucagon, a 29-amino-acid, straight-chain polypeptide of α-cell pancreatic origin, triggers liver glycogenolysis and gluconeogenesis, thereby elevating glucose levels. The principal action of glucagon is the liver-mediated release into the blood of abnormally high concentrations of glucose, which causes hyperglycemia. This means that glucagon has an effect on blood glucose levels that is opposite to what occurs with insulin.
General Description
produced by recombinant DNA technology ismarketed by Novo Nordisk (glucagon [recombinant] hydrochloride,GlucaGen HypoKit, GlucaGen Diagnostic Kit)and by Eli Lilly (glucagon [recombinant] Emergency Kit).
Clinical Use
Endogenous glucagon isproduced from the gene-derived protein PG in the cells ofthe islets of Langerhans in the pancreas. The core functionof this hormone is to renormalize blood glucose levels whenthey fall too low, by stimulating production from glycogen stores in liver and muscle, and stimulating hepatic gluconeogenesis.Glucagon also elicits biochemical processes (suchas fatty acid oxidation) that supply the needed precursors forgluconeogenesis. Glucagon supplied exogenously (i.e., injected)in response to emergency hypoglycemia acts rapidlyto elicit these same responses. Clinically, glucagon also providesan alternative to cholinergic antagonists for reducingGI motility and secretory activity during radiologic imagingprocedures.
Glucagon Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Manus Aktteva | +91 (79) 6512-3395 | New Delhi, India | 581 | 34 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Apeloa production Co.,Limited | +8619933239880 | China | 853 | 58 | Inquiry |
Cellmano Biotech Limited | 0551-65326643 18156095617 | China | 999 | 58 | Inquiry |
Apextide Co Ltd | +86-15300650552 +86-15300650552 | China | 71 | 58 | Inquiry |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
Zhejiang Hangyu API Co., Ltd | +8617531972939 | China | 2944 | 58 | Inquiry |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 | China | 265 | 58 | Inquiry |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | China | 2503 | 58 | Inquiry |
qingdao future trading Co., Ltd | +86-13335044410 +86-13335044410 | China | 110 | 58 | Inquiry |
Related articles
- Exploring Glucagon's Role in Insulin Secretion and its Implications for Diabetes Treatment
- Glucagon's role in insulin secretion can be targeted with GCGR antagonists and GLP-1R agonists for diabetes treatment.
- Feb 6,2024
- What is Glucagon?
- Glucagon regulates blood sugar, which is the opposite of insulin.
- Sep 25,2023
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