DOXYLAMINE
- CAS No.
- 469-21-6
- Chemical Name:
- DOXYLAMINE
- Synonyms
- oxylamine;Dosilamin;DOXYLAMINE;NCI C60684;DOXYLAMINE USP/EP/BP;Doxylamine Hydrogen inate;2-dimethylaminoethoxyphenylmethyl-2-picoline;alpha-Dimethylaminoethoxyphenylmethyl-2-picoline;2-[a-(2-dimethylaminoethoxy)-a-methylbenzyl]pyridine;dimethyl(2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl)amine
- CBNumber:
- CB6316736
- Molecular Formula:
- C17H22N2O
- Molecular Weight:
- 270.37
- MOL File:
- 469-21-6.mol
- Modify Date:
- 2024/3/19 15:37:51
| Melting point | 25°C |
|---|---|
| Boiling point | bp0.5 137-141° |
| Density | 1.0023 (rough estimate) |
| refractive index | 1.5486 (estimate) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| pka | pKa 9.20(H2O t = 25 c = 0.002–0.01) (Uncertain);4.4 (Uncertain);9.2 (Uncertain) |
| color | Colourless |
| Stability | Temperature Sensitive |
| EPA Substance Registry System | Doxylamine (469-21-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| Toxicity | An antihistamine that formerly was used in pregnant women for antihistaminic and sedative properties. Although it has excellent sedative properties, it has been implicated in teratogenesis and in causing neurobehavioral toxicity and is therefore no longer used |
DOXYLAMINE Chemical Properties,Uses,Production
Uses
(±)-Doxylamine is an intermediate in the synthesis of Doxylamine N, N’-Dioxide (D562025), which is an impurity of Doxylamine (succinate salt, D562000), which is an H1 Histamine receptor antagonist.
General Description
Clear colorless liquid.
Reactivity Profile
DOXYLAMINE is an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides
DOXYLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 54)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | China | 305 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | China | 2255 | 58 | Inquiry |
| Shijiazhuang Gantuo Biotechnology Co., Ltd | +8613373514458 | China | 218 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | China | 9003 | 58 | Inquiry |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | China | 3582 | 58 | Inquiry |
469-21-6(DOXYLAMINE)Related Search:
N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine
NCI C60684
Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether
Pyridine, 2-[alpha-[2-(dimethylamino)ethoxy]-alpha-methylbenzyl]-
DOXYLAMINE
dimethyl(2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl)amine
2-[a-(2-dimethylaminoethoxy)-a-methylbenzyl]pyridine
2-dimethylaminoethoxyphenylmethyl-2-picoline
phenyl-2-pyridylmethyl-b-N,N-dimethylaminoethyl ether
Doxylamine Hydrogen inate
2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine
alpha-Dimethylaminoethoxyphenylmethyl-2-picoline
Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-
oxylamine
DOXYLAMINE USP/EP/BP
Dosilamin
469-21-6