Doxylamine succinate
![Doxylamine succinate Structure](CAS/GIF/562-10-7.gif)
- CAS No.
- 562-10-7
- Chemical Name:
- Doxylamine succinate
- Synonyms
- unisom;decapryn;hoggarn;gittalun;sedaplus;alsadorm;mereprine;DoxylaMineSuccinat;Decapryn succinate;DOXYLAMINE SUCCINATE
- CBNumber:
- CB9416701
- Molecular Formula:
- C21H28N2O5
- Molecular Weight:
- 388.46
- MOL File:
- 562-10-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:42
Melting point | 95-98?C |
---|---|
Flash point | 9℃ |
storage temp. | 2-8°C |
solubility | Very soluble in water, freely soluble in ethanol (96 per cent). |
form | Solid |
color | White to Off-White |
Stability | Stable, but may be light sensitive. Incompatible with strong oxidizing agents, acids, bases. |
InChIKey | KBAUFVUYFNWQFM-UHFFFAOYSA-N |
LogP | 2.519 (est) |
CAS DataBase Reference | 562-10-7(CAS DataBase Reference) |
IARC | 3 (Vol. 79) 2001 |
EPA Substance Registry System | Doxylamine succinate (1:1) (562-10-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332-H335 | |||||||||
Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
Hazard Codes | Xn,T,F | |||||||||
Risk Statements | 22-36/37/38-20/21/22-39/23/24/25-23/24/25-11 | |||||||||
Safety Statements | 26-36/37-45-16-7 | |||||||||
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
WGK Germany | 2 | |||||||||
RTECS | US9275000 | |||||||||
HS Code | 2933399090 | |||||||||
Toxicity | LD50 in mice, rabbits (mg/kg): 470, 250 orally; 62, 49 i.v.; in mice, male rats, female rats (mg/kg): 460, 440, 445 s.c. (Brown, Werner) | |||||||||
NFPA 704 |
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Doxylamine succinate price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D3775 | Doxylamine succinate salt | 562-10-7 | 5G | ₹8324.43 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1420 | Doxylamine Succinate Pharmaceutical Secondary Standard; Certified Reference Material | 562-10-7 | 1G | ₹13238.98 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D3775 | Doxylamine succinate salt | 562-10-7 | 50G | ₹48214.55 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D-045 | Doxylamine succinate solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 562-10-7 | 1ML | ₹4575.2 | 2022-06-14 | Buy |
TCI Chemicals (India) | D5583 | Doxylamine Succinate | 562-10-7 | 5G | ₹6300 | 2022-05-26 | Buy |
Doxylamine succinate Chemical Properties,Uses,Production
Chemical Properties
white to light cream powder
Uses
Doxylamine succinate salt has been used as a therapeutic drug to check developmental toxicity.
General Description
The acid succinate salt (bisuccinate)of doxylamine, 2-[ -[2-(dimethylamino)ethoxy]- -methylbenzyl]pyridine bisuccinate (Decapryn Succinate), isa white to creamy-white powder with a characteristic odor.It is soluble in water (1:1), alcohol (1:2), and chloroform(1:2). A 1% solution has a pH of about 5.Doxylamine succinate is comparable in potency todiphenhydramine. It is indicated for the relief of seasonalrhinitis symptoms, but is also used as a nighttime sedative.Concurrent use of alcohol and other CNS depressantsshould be avoided.
Air & Water Reactions
Water soluble.
Health Hazard
SYMPTOMS: Symptoms of exposure to Doxylamine succinate may include drowsiness, excitability, nervousness, dizziness and sleeplessness.
Fire Hazard
Flash point data for Doxylamine succinate are not available. Doxylamine succinate is probably combustible.
Doxylamine succinate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
PRODIGIOUS LIFE SCIENCES | +91-9177472555 +91-9177472555 | Hyderabad, India | 236 | 58 | Inquiry |
Vivimed Labs Ltd | +914066086608 | Telangana, India | 61 | 58 | Inquiry |
Malladi Drugs AND Pharmaceuticals Limited | +91-9004653310 +91-9003056437 | Tamil Nadu, India | 69 | 58 | Inquiry |
Anugraha Chemicals | +91-8041685494 +91-9845939733 | Karnataka, India | 22 | 58 | Inquiry |
R L Fine Chem Pvt. Ltd | +91-8042488999 +91-8042488999 | Karnataka, India | 74 | 58 | Inquiry |
Aruvi Labs | +91-8056181939 +91-8056181939 | Tamil Nadu, India | 149 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Urmila Chemopharma | +91-9819537618 +91-8928751722 | Maharashtra, India | 25 | 58 | Inquiry |
Ar Ex Laboratories Pvt Ltd | 91-22-24454109 | Maharashtra, India | 18 | 58 | Inquiry |
Supplier | Advantage |
---|---|
PRODIGIOUS LIFE SCIENCES | 58 |
Vivimed Labs Ltd | 58 |
Malladi Drugs AND Pharmaceuticals Limited | 58 |
Anugraha Chemicals | 58 |
R L Fine Chem Pvt. Ltd | 58 |
Aruvi Labs | 58 |
Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
Ralington Pharma | 58 |
Urmila Chemopharma | 58 |
Ar Ex Laboratories Pvt Ltd | 58 |
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