AZD2098

AZD2098 Structure
CAS No.
566203-88-1
Chemical Name:
AZD2098
Synonyms
AZD2098;AZD 2098 NEW;AZD-2098 >=98% (HPLC);AZD 2098;AZD-2098;AZD2098;2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide;Benzenesulfonamide, 2,3-dichloro-N-(3-methoxy-2-pyrazinyl)-;AZD-2098,inhibit,CC chemokine receptor,CCR,Inhibitor,AZD2098,AZD 2098
CBNumber:
CB63175527
Molecular Formula:
C11H9Cl2N3O3S
Molecular Weight:
334.18
MOL File:
566203-88-1.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

AZD2098 Properties

Melting point 185-186°C
Boiling point 489.3±55.0 °C(Predicted)
Density 1.569±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DMSO (>25 mg/ml)
pka 5.56±0.40(Predicted)
form powder
color white to beige
Stability Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

AZD2098 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML2272 AZD-2098 ≥98% (HPLC) 566203-88-1 5MG ₹10684.28 2022-06-14 Buy
Sigma-Aldrich(India) SML2272 AZD-2098 ≥98% (HPLC) 566203-88-1 25MG ₹43061.85 2022-06-14 Buy
Product number Packaging Price Buy
SML2272 5MG ₹10684.28 Buy
SML2272 25MG ₹43061.85 Buy

AZD2098 Chemical Properties,Uses,Production

Biochem/physiol Actions

AZD-2098 is an orally active, potent and selective CCR4 antagonist (pIC50 = 7.8/8.0/8.0/7.6 against CCL22 binding to human/mouse/rat/dog CCR4; inactive toward CXCR1/2 & CCR1/2b/5/7/8 at 10 μM) with little or no activity toward a panel of ~120 receptors/enzymes. AZD-2098 effectively inhibits chemokine-induced cellular responses in vitro (pIC50 = 7.5 against CCL22-induced calcium influx in hCCR4-expressing CHO cells; pIC50 = 6.3 against CCL17- or CCL22-induced chemotaxis of primary human Th2 cells) and exhibits efficacy against antigen-induced inflammatory response among ovalbumin-sensitized rats in vivo (Emax = 7.5 μmol/kg p.o.; 1 h before and every 12 h after antigen challenge).

AZD2098 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 54)Suppliers
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ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Chunchuang (Wuhan) Technology Co., Ltd 15342225168 China 10005 58 Inquiry
Bide Pharmatech Ltd. 400-1647117 15221909166 China 63720 58 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9650 58 Inquiry
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 China 10010 58 Inquiry
AZD2098 AZD 2098 NEW AZD 2098;AZD-2098;AZD2098 2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide Benzenesulfonamide, 2,3-dichloro-N-(3-methoxy-2-pyrazinyl)- AZD-2098 >=98% (HPLC) AZD-2098,inhibit,CC chemokine receptor,CCR,Inhibitor,AZD2098,AZD 2098 566203-88-1 C11H9Cl2N3O3S