AZD2098
![AZD2098 Structure](CAS/20200611/GIF/566203-88-1.gif)
- CAS No.
- 566203-88-1
- Chemical Name:
- AZD2098
- Synonyms
- AZD2098;AZD 2098 NEW;AZD-2098 >=98% (HPLC);AZD 2098;AZD-2098;AZD2098;2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide;Benzenesulfonamide, 2,3-dichloro-N-(3-methoxy-2-pyrazinyl)-;AZD-2098,inhibit,CC chemokine receptor,CCR,Inhibitor,AZD2098,AZD 2098
- CBNumber:
- CB63175527
- Molecular Formula:
- C11H9Cl2N3O3S
- Molecular Weight:
- 334.18
- MOL File:
- 566203-88-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
Melting point | 185-186°C |
---|---|
Boiling point | 489.3±55.0 °C(Predicted) |
Density | 1.569±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Soluble in DMSO (>25 mg/ml) |
pka | 5.56±0.40(Predicted) |
form | powder |
color | white to beige |
Stability | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
AZD2098 price More Price(2)
AZD2098 Chemical Properties,Uses,Production
Biochem/physiol Actions
AZD-2098 is an orally active, potent and selective CCR4 antagonist (pIC50 = 7.8/8.0/8.0/7.6 against CCL22 binding to human/mouse/rat/dog CCR4; inactive toward CXCR1/2 & CCR1/2b/5/7/8 at 10 μM) with little or no activity toward a panel of ~120 receptors/enzymes. AZD-2098 effectively inhibits chemokine-induced cellular responses in vitro (pIC50 = 7.5 against CCL22-induced calcium influx in hCCR4-expressing CHO cells; pIC50 = 6.3 against CCL17- or CCL22-induced chemotaxis of primary human Th2 cells) and exhibits efficacy against antigen-induced inflammatory response among ovalbumin-sensitized rats in vivo (Emax = 7.5 μmol/kg p.o.; 1 h before and every 12 h after antigen challenge).
AZD2098 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 54)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48467 | 58 | Inquiry |
Chunchuang (Wuhan) Technology Co., Ltd | 15342225168 | China | 10005 | 58 | Inquiry |
Bide Pharmatech Ltd. | 400-1647117 15221909166 | China | 63720 | 58 | Inquiry |
Olix (Shanghai) Pharmaceutical Technology Co., Ltd | 17316404525 | China | 9650 | 58 | Inquiry |
Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | China | 10010 | 58 | Inquiry |
566203-88-1(AZD2098)Related Search:
AZD2098
AZD 2098 NEW
AZD 2098;AZD-2098;AZD2098
2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide
Benzenesulfonamide, 2,3-dichloro-N-(3-methoxy-2-pyrazinyl)-
AZD-2098 >=98% (HPLC)
AZD-2098,inhibit,CC chemokine receptor,CCR,Inhibitor,AZD2098,AZD 2098
566203-88-1
C11H9Cl2N3O3S