CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-

CAS No.: 168960-18-7

Chemical Name:: CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-

Synonyms: TERT-BUTYL (1R,4S)-4-(HYDROXYMETHYL)CYCLOPENT-2-ENYLCARBAMATE;tert-Butyl ((1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)carbamate;TERT-BUTYL CIS-[4(S)-(HYDROXYMETHYL)CYCLOPENT-2-EN-1(R)-YL]CARBAMATE;Carbamic acid, [(1R,4S)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-, 1,1-;(1R,4S)-N-(tert-Butyloxycarbonyl)-1-amino-4-(hydroxymethyl)-2-cyclopentene;1-((1R,4S)-4-(Hydroxymethyl)cyclopent-2-en-1-yl)-2-methylpropan-2-yl carbamate;N-[(1R,4S)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]-carbamic Acid 1,1-Dimethylethyl Ester;Carbamic acid, N-[(1R,4S)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-, 1,1-dimethylethyl ester;CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-

CBNumber:: CB6326249

Molecular Formula:: C11H19NO3

Molecular Weight:: 213.27

MOL File:: 168960-18-7.mol

MSDS File:: SDS

Modify Date:: 2023/5/4 15:16:11

Request For Quotation

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- Properties

Boiling point	338.8±31.0 °C(Predicted)
Density	1.09±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO; Methanol
pka	12.06±0.40(Predicted)
form	Oil
color	Yellow

SAFETY

Risk and Safety Statements

Hazard statements	H412
Precautionary statements	P273-P501

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- Chemical Properties,Uses,Production

Uses

N-?[(1R,?4S)?-?4-?(Hydroxymethyl)?-?2-?cyclopenten-?1-?yl]?-carbamic Acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing ent-Abacavir (Abacavir EP Impurity A) (A105015), an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- Preparation Products And Raw materials

Raw materials

Preparation Products

(1S-cis)-4-Amino-2-cyclopentene-1-methanol

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- Suppliers

Global( 19)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd.	15800340161	CHINA	6846	58	Inquiry
Combi-Blocks Inc.	858 635 8950	United States	6632	69	Inquiry
Nanjing Dalton chemical technology company limited	15051832550	China	160	58	Inquiry
Aikon International Limited	025-58859352 18068836627	China	15085	58	Inquiry
Shaanxi Didu New Material Co., Ltd	029-63373950 15353716720	China	10011	58	Inquiry
Shanghai Haohong Pharmaceutical Co., Ltd.	4008210725 4008210725	China	55023	58	Inquiry
LONZA Inc.	201 316 9200	United States	252	81	Inquiry

Supplier	Advantage
A.J Chemicals	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Shanghai Hao Zhun Biological Technology Co., Ltd.	58
Combi-Blocks Inc.	69
Nanjing Dalton chemical technology company limited	58
Aikon International Limited	58
Shaanxi Didu New Material Co., Ltd	58
Shanghai Haohong Pharmaceutical Co., Ltd.	58
LONZA Inc.	81

168960-18-7(CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-)Related Search:

(-)-(1S,4R)-N-BOC-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID Carbamic acid, 4-pentenyl-, 1,1-dimethylethyl ester (9CI) 1-N-BOC-AMINO-2-CYCLOPENTENE TERT-BUTYL N-ALLYLCARBAMATE CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-

(1S-cis)-4-Amino-2-cyclopentene-1-methanol

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TERT-BUTYL CIS-[4(S)-(HYDROXYMETHYL)CYCLOPENT-2-EN-1(R)-YL]CARBAMATE CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- Carbamic acid, [(1R,4S)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-, 1,1- TERT-BUTYL (1R,4S)-4-(HYDROXYMETHYL)CYCLOPENT-2-ENYLCARBAMATE tert-Butyl ((1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)carbamate (1R,4S)-N-(tert-Butyloxycarbonyl)-1-amino-4-(hydroxymethyl)-2-cyclopentene 1-((1R,4S)-4-(Hydroxymethyl)cyclopent-2-en-1-yl)-2-methylpropan-2-yl carbamate N-[(1R,4S)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]-carbamic Acid 1,1-Dimethylethyl Ester Carbamic acid, N-[(1R,4S)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-, 1,1-dimethylethyl ester 168960-18-7 N-BOC