Dansyl ethylenediamine
- CAS No.
- 35060-08-3
- Chemical Name:
- Dansyl ethylenediamine
- Synonyms
- DNSEDA;NSC 666752;DANSYL ETHYLENEDIAMINE;N-Dansylethylenediamine;(2-AMINOETHYL)-DANSYLAMIDE;N-(2-Aminoethyl)dansylamide;2-(5-DiMethylaMino-1-naphthalenesulfonaMido)ethylaMine;5-DIMETHYLAMINONAPHTHALENE-1-(N-(2-AMINOETHYL))-SULFONAMIDE;N-(2-AMinoethyl)-5-(diMethylaMino)-1-naphthalenesulfonaMide;N-(2-aminoethyl)-5-(dimethylamino)naphthalene-1-sulfonamide
- CBNumber:
- CB6328834
- Molecular Formula:
- C14H19N3O2S
- Molecular Weight:
- 293.38
- MOL File:
- 35060-08-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/14 14:46:44
Melting point | 145-146°C |
---|---|
Boiling point | 470.2±55.0 °C(Predicted) |
Density | 1.262±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | methanol: soluble1mg/mL, clear, slightly yellow to deep yellow |
form | Solid |
pka | 11.30±0.50(Predicted) |
color | Light Yellow |
BRN | 2817535 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38 |
Safety Statements | 26 |
WGK Germany | 3 |
HS Code | 38220090 |
Dansyl ethylenediamine Chemical Properties,Uses,Production
Description
Dansyl ethylenediamine is a lipophilic fluorophore that can be coupled to coarboxylic acids of proteins and other water-soluble polymers. The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Spectral data: λex=335nm, λem=525nm in methanol. Dansyl ethylenediamine has also shown to inhibit human renal dipeptidase (hrDP) irreversibly in a time-dependent manner.
Chemical Properties
Yellow to orange powder.
References
[1] YUKI INOUE. Fluorescent molecularly imprinted polymer thin films for specific protein detection prepared with dansyl ethylenediamine-conjugated O-acryloyl l-hydroxyproline[J]. Biosensors and Bioelectronics, 2013. DOI:10.1016/j.bios.2013.03.005.
[2] ADACHIH. Importance of Glu-125 in the catalytic activity of human renal dipeptidase.[J]. Biochimica et biophysica acta, 1993. DOI:10.1016/0167-4838(93)90276-w.
[3] MALLAMPATI S, AERSCHOT A V, HOOGMARTENS J, et al. Analysis of dideoxyadenosine triphosphate by CE with fluorescence detection. I. Derivatization through the phosphate group[J]. ELECTROPHORESIS, 2007, 28. DOI:10.1002/elps.200700234.
[4] DUDLEY R W, SLOTTERBECK B D, MCINERNEY M F, et al. Fatty acylation enhances cellular localization of dansylated phenylalanines[J]. Molecular and Cellular Biochemistry, 2010, 346: 81-87. DOI:10.1007/s11010-010-0593-4.
Dansyl ethylenediamine Preparation Products And Raw materials
Raw materials
Preparation Products
Dansyl ethylenediamine Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | China | 19185 | 58 | Inquiry |
Aceschem Inc. | +1-817863-6948 +1-(817)863-6948 | United States | 19639 | 58 | Inquiry |
Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
HUNAN CHEMFISH SCIENTIFIC CO.,LTD | 13021512891 | China | 6866 | 58 | Inquiry |
Hunan chemfish Scientific co.,ltd | 0731-85567275 15528049369 | China | 4898 | 58 | Inquiry |
CHO Chemical Materials Chang Zhou CO., LTD | 15995034354 | China | 2707 | 58 | Inquiry |
Hangzhou J&H Chemical Co., Ltd. | +86-571-87396432 | China | 10063 | 53 | Inquiry |
TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | China | 31163 | 58 | Inquiry |
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