Ethylenediamine
- CAS No.
- 107-15-3
- Chemical Name:
- Ethylenediamine
- Synonyms
- EDA;ETHANE-1,2-DIAMINE;1,2-DIAMINOETHANE;YEA;1,2-ETHANEDIAMINE;Ethylendiamine;1,2-Ethylenediamine;Diaminoethane;H2NCH2CH2NH2;Ethyleendiamine
- CBNumber:
- CB2127811
- Molecular Formula:
- C2H8N2
- Molecular Weight:
- 60.1
- MOL File:
- 107-15-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/14 15:18:26
| Melting point | 8.5 °C (lit.) |
|---|---|
| Boiling point | 118 °C (lit.) |
| Density | 0.899 g/mL at 25 °C (lit.) |
| vapor density | 2.07 (vs air) |
| vapor pressure | 10 mm Hg ( 20 °C) |
| refractive index |
n |
| Flash point | 93 °F |
| storage temp. | Flammables area |
| solubility | ethanol: soluble(lit.) |
| pka | 10.712(at 0℃) |
| form | Liquid, Fuming In Air |
| Specific Gravity | 0.899 |
| color | colorless to pale yellow |
| PH | 12.2 (100g/l, H2O, 20℃) |
| Odor | Strong ammoniacal odor; ammonia-like mild and ammoniacal odor. |
| explosive limit | 2-17%(V) |
| Water Solubility | miscible |
| Sensitive | Air Sensitive |
| Merck | 14,3795 |
| BRN | 605263 |
| Henry's Law Constant | 1.69(x 10-9 atm?m3/mol) at 25 °C (Westheimer and Ingraham, 1956) |
| Exposure limits | TLV-TWA 10 ppm (～25 mg/m3) (ACGIH, MSHA, and OSHA); IDLH 2000 ppm (NIOSH). |
| Dielectric constant | 16.0（18℃） |
| InChIKey | PIICEJLVQHRZGT-UHFFFAOYSA-N |
| LogP | -1.6 at 20℃ |
| CAS DataBase Reference | 107-15-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethylenediamine(107-15-3) |
| EPA Substance Registry System | Ethylenediamine (107-15-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS02,GHS05,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302+H332-H311-H314-H317-H334-H412 | |||||||||
| Precautionary statements | P210-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 10-21/22-34-42/43 | |||||||||
| Safety Statements | 23-26-36/37/39-45 | |||||||||
| OEB | A | |||||||||
| OEL | TWA: 10 ppm (25 mg/m3) | |||||||||
| RIDADR | UN 1604 8/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | KH8575000 | |||||||||
| F | 10-34 | |||||||||
| Autoignition Temperature | 716 °F | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29212110 | |||||||||
| Toxicity | LD50 orally in rats: 1.16 g/kg (Smyth) | |||||||||
| IDLA | 1,000 ppm | |||||||||
| NFPA 704 |
|
Ethylenediamine price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | E26266 | Ethylenediamine ReagentPlus?, ≥99% | 107-15-3 | 5ML | ₹2468.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E26266 | Ethylenediamine ReagentPlus?, ≥99% | 107-15-3 | 100ML | ₹3031 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E26266 | Ethylenediamine ReagentPlus?, ≥99% | 107-15-3 | 500ML | ₹3832.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E26266 | Ethylenediamine ReagentPlus?, ≥99% | 107-15-3 | 1L | ₹4676.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E26266 | Ethylenediamine ReagentPlus?, ≥99% | 107-15-3 | 2.5L | ₹5152.7 | 2022-06-14 | Buy |
Ethylenediamine Chemical Properties,Uses,Production
Description
Ethylenediamine is used in numerous industrial proces ses as a solvent for casein or albumin, as a stabilizer in rubber latex and as a textile lubricant. It can be found in epoxy-resin hardeners, cooling oils, fungicides, and waxes. Contact dermatitis from ethylenediamine is almost exclusively due to topical medicaments. Occupational contact dermatitis in epoxy-resin systems is rather infrequent. Ethylenediamine can cross react with triethylenetetramine and diethylenetriamine. Ethylenediamine was responsible for sensitization in pharmacists handling aminophylline suppositories, in nurses preparing and administering injectable theophylline, and in a laboratory technician in the manufacture of aminophylline tab lets.
Chemical Properties
Ethylenediamine, a polyamine, is a strongly alkaline, colorless, clear, thick liquid. Ammonia odor. A solid below 8.5℃. The Odor Threshold is 1.0 ppm
Physical properties
Clear, colorless, volatile, slight viscous, hygroscopic liquid with a sweet, ammonia-like odor. The average least detectable odor threshold concentrations in water at 60 °C and in air at 40 °C were 12 and 52 mg/L, respectively (Alexander et al., 1982).
Uses
[Note—Edamine is the recommended contraction for the ethylenediamine radical.].
Production Methods
The production of ethylene-1,2-diamine (EDA) is by the catalytic amination of monoethanolamine or the reaction of aqueous ammonia with 1,2-dichloroethane (Spitz 1979). U.S. Production is estimated at greater than 33,000 tons in 1975.
Definition
ChEBI: An alkane-alpha,omega-diamine in which the alkane is ethane.
General Description
Ethylenediamine is a linear aliphatic diamine, widely used as a building block in organic synthesis. It readily forms heterocyclic imidazolidine derivatives, because of its bifunctional nature, having two amines. Ethylenediamine is also utilized as a raw material for the synthesis of chelating agents, polymers, agrochemicals and pharmaceutical intermediates.
Air & Water Reactions
Highly flammable. Hygroscopic. Fumes in the air. Water soluble. Biodegrades readily.
Reactivity Profile
A base. Highly reactive with many compounds. Can react violently with acetic acid, acetic anhydride, acrolein, acrylic acid, acrylonitrile, allyl chloride, carbon disulfide, chlorosulfonic acid, epichlorohydrin, ethylene chlorohydrin, hydrogen chloride, mesityl oxide, nitric acid, oleum, AgClO4, sulfuric acid, beta-propiolactone and vinyl acetate. Incompatible with strong acids, strong oxidizers (perchlorate salts), and chlorinated organic compounds. Ethylenediamine is also incompatible with halogenated organic compounds and metal halides. May react with nitromethane and diisopropyl peroxydicarbonate. May ignite on contact with cellulose nitrate. Readily absorbs carbon dioxide from the air to give crusty solid deposits. . Ethylenediamine reacts violently with ethylene chlorohydrin. (Lewis, R.J., Sr. 1992. Sax's Dangerous Properties of Industrial Materials, 8th Edition. New York: Van Nostrand Reinhold. pp. 1554.).
Hazard
Toxic by inhalation and skin absorption, strong irritant to skin and eyes. Flammable, moderate fire risk. Questionable carcinogen.
Health Hazard
Ethylenediamine is a severe skin irritant, producing sensitization, an allergic reaction andblistering on the skin. Pure liquid on contact with the eyes can damage vision. A25% aqueous solution can be injurious to theeyes. Inhalation of its vapors can producea strong irritation to the nose and respiratory tract leading to chemical pneumonitis and pulmonary edema. Such irritation inhumans with symptoms of cough and dis tressed breathing may be noted at concentrations of >400 ppm. Repeated exposure tohigh concentrations of this substance in airmay cause lung, liver, and kidney damage.The toxicity of this compound, however, is much less than that of ethylenimine.The acute oral toxicity value in animalswas low to moderate. An oral LD50 value inrats is 500 mg/kg (NIOSH 1986).
Fire Hazard
Burning rate: 2.2 mm/minute. When exposed to heat or flame, the material has a moderate fire potential. The material can react readily with oxidizing materials. Containers may explode in heat of fire. Material emits nitrogen oxides when burned. Avoid carbon disulfide, silver perchlorate, imines, oxidizing materials. Stable. Hazardous polymerization may not occur.
Chemical Reactivity
Reactivity with Water Gives off heat, but reaction is not hazardous; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Flush with water; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Industrial uses
EDA functions as a reactive intermediate in the synthesis of carbamate fungicides and in the preparation of dyes, synthetic waxes, resins, insecticides and asphalt wetting agents (Parmeggiani 1983). EDA is a solvent for casein, albumin, shellac, and sulfur; an emulsifier; a stabilizer for rubber latex; an inhibitor in antifreeze solutions; and a pharmaceutic aid (aminophylline injection stabilizer) (Windholz 1983). It is also an important ingredient in hair-settings, cold wave lotions, and nail polish (Arena 1979).
Contact allergens
Ethylenediamine is used in numerous industrial processes as a solvent for casein or albumin, as a stabilizer in rubber latex, and as a textile lubricant. It can be found in epoxy resin hardeners, cooling oils, fungicides, and waxes. Contact dermatitis from ethylenediamine is almost exclusively due to topical medicaments. Occupational contact dermatitis in epoxy resin systems is rather infrequent. Ethylenediamine can crossreact with triethylenetetramine and diethylenetriamine. Ethylenediamine was found to be responsible for sensitization in pharmacists handling aminophylline suppositories, in nurses preparing and administering injectable theophylline, and in a laboratory technician in the manufacture of aminophylline tablets
Safety Profile
A human poison by inhalation. Experimental poison by inhalation, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion and skin contact, Experimental reproductive effects. Corrosive. A severe skin and eye irritant. An allergen and sensitizer. Mutation data reported. Flammable liquid when exposed to heat, flame, or oxidizers. Can react violently with acetic acid, acetic anhydride, acrolein, acrylic acid, acrylonitrile, allyl chloride, CS2, chlorosulfonic acid, epichlorohydrin, ethylene chlorohydrin, HCl, mesityl oxide, HNO3, oleum, AgClO4, H2SO4, Ppropiolactone, or vinyl acetate. To fight fwe, use CO2, dry chemical, alcohol foam. When heated to decomposition it emits toxic fumes of NOx and NH3. See also MINES.
Potential Exposure
Ethylenediamine is used as an intermediate; as a urine acidifier; as a solvent; an emulsifier for casein and shellac solutions; a stabilizer in rubber late. A chemical intermediate in the manufacture of dyes; corrosion inhibitors; synthetic waxes; fungicides, resins, insecticides, asphalt wetting agents; and pharmaceuticals. Ethylenediamine is a degradation product of the agricultural fungicide Maneb.
Environmental Fate
Chemical/Physical. Absorbs carbon dioxide forming carbonates (Patnaik, 1992; Windholz et al.,
1983).
At an influent concentration of 1,000 mg/L, treatment with GAC resulted in an effluent
concentration of 893 mg/L. The adsorbability of the carbon used was 21 mg/g carbon (Guisti et
al., 1974).
Shipping
UN1604 Ethylenediamine, Hazard class: 8; Labels: 8-Corrosive material, 3-Flammable liquid
Incompatibilities
Vapor may form explosive mixture with air. Ethylenediamine is a medium strong base. Violent reaction with strong acids; strong oxidizers; chlorinated organic compounds; acetic acid; acetic anhydride; acrolein, acrylic acid; acrylonitrile, allyl chloride; carbon disulfide; chlorosulfonic acid; epichlorohydrin, ethylene chlorohydrin, oleum, methyl oxide; vinyl acetate. Also incompatible with silver perchlorate, 3-propiolactone, mesityl oxide; ethylene dichloride; organic anhydrides; isocyanates, acrylates, substituted allyls; alkylene oxides; ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks aluminum, copper, lead, tin, zinc, and alloys; some plastics, rubber, and coatings.
Waste Disposal
Controlled incineration (oxides of nitrogen are removed from the effluent gas by scrubbers and/or thermal devices).
Ethylenediamine Preparation Products And Raw materials
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