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(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Structure
CAS No.
98760-08-8
Chemical Name:
(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane
Synonyms
(2r,3s)-3-(n-boc-amino)-1-oxirane-4-phenylbutane;(2R,3S)-BOC-E;(2R,3S)-Boc-Epoxide;(2R,3S)-3-(N-BOC-AMI;(1S,2R)-Boc epoxide  ;Atazanavir Impurity C;2-epoxy-4-phenylbutane;Atazanavir Impurity 20;3S)-3-(tert-Butoxycarbonyl)aMino-1;THREO-N-BOC-L-PHENYLALANINE EPOXIDE
CBNumber:
CB6339142
Molecular Formula:
C15H21NO3
Molecular Weight:
263.34
MOL File:
98760-08-8.mol
Modify Date:
2024/4/16 14:59:45

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Properties

Melting point 50-52°C
Boiling point 398.8±25.0 °C(Predicted)
Density 1.118±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 12.19±0.46(Predicted)
color White to Off-White
CAS DataBase Reference 98760-08-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  29242998

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Powder

Uses

Atazanavir intermediate. Enantiomer R

Application

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane is an intermediate of the HIV-1 protease inhibitor atazanavir (sc-207305) and aslo an intermediate of amprenavir.

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Preparation Products And Raw materials

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(2R, 3S)-1,2-EPOXY-3-N-(TERT-BUTOXYCARBONYL)AMINO-4-PHENYLBUTANE (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane [1(S)-BENZYL-2(R),3-EPOXYPROPYL]-CARBAMIC ACID TERT-BUTYL ESTER THREO-N-BOC-L-PHENYLALANINE EPOXIDE TERT-BUTYL (1S)-1-[(2R)-OXIRAN-2-YL]-2-PHENYLETHYLCARBAMATE Tert-Butyl[(1S)-1-(2R)-Oxiranyl-2-Phenylethyl]carbamate Carbamic acid,[(1S)-1-(2R)-oxiranyl-2-phenylethyl]-,1,1-dimethylethyl ester (2R,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane (2R,3S)-1,2-Epoxy-3-N-(tert-butoxycarbonyl)amino- (2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane [(1S)-1-((2R)-Oxiranyl)-2-phenylethyl]carbamic Acid tert-Butyl Ester N-[(1S)-1-[(2R)-2-Oxiranyl]-2-phenylethyl]-carbamic Acid 1,1-Dimethylethyl Ester tert-Butyl[(1S,2R)-oxiranyl-2-phenylethyl]carbamate (1S,2R)-Boc epoxide   (RS) BOC EPOXIDE // 2,R - 3S, - 3 - N - TERT - BUT Carbamic acid, N-[(1S)-1-[(2R)-2-oxiranyl]-2-phenylethyl]-, 1,1-dimethylethyl ester TERT-BUTYL (S)-1-((R)-OXIRAN-2-YL)-2-PHENYLETHYLCARBAMATE (2R,3S)-3-(N-BOC-amino)-1-oxirane-4-phenylbutane,98% 2-epoxy-4-phenylbutane 3S)-3-(tert-Butoxycarbonyl)aMino-1 "[(1S)-1-(2R)-oxiranyl-2-phenylethyl]-carbaMic acid- 1,1-diMethylethyl ester" [(1S)-1-(2R)-oxiranyl-2-phenylethyl]-, 1,1-diMethylethyl ester (2R,3S)-3-(t-BOC)amino-1,2-epoxy-4-phenylbutane (2R,3S)-3-(N-BOC-aMino)-1-oxirane-4-phenylbutane, 98% 5GR 2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane,Carbamic acid, N-[(1S)-1-(2R)-2-oxiranyl-2-phenylethyl]-, 1,1-dimethylethyl ester [(1S)-1-((2R)-Oxiranyl)-2-phenylethyl]carbaMic Acid tert- (2S, 3R)-1, 2-Epoxy-3-(Boc-aMino)-4-Phenylbutane (2R,3S)-N-Boc-3-amino-1,2-epoxy-4-Phenylbutane(Boc Epoxy) threo-N-Boc-L-phenylalanine epoxide≥ 99% (HPLC) Atazanavir Impurity C (2R,3S)-3-[N-(tert-butyloxycarbonyl)amino]-1,2-epoxy-4-phenylbutane (1S) -1- (2R) -Ethoxyethyl-2-phenethylcarbamic acid tert-butyl ester / atazanavir intermediate Atazanavir Impurity 20 (2R,3S)-3-(N-BOC-AMI tert-butyl N-[(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate (2R,3S)-Boc-Epoxide (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane [Boc-Epoxide] (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane ISO 9001:2015 REACH (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy- 4-phenylbutane(2R3S Epoxide) (2r,3s)-3-(n-boc-amino)-1-oxirane-4-phenylbutane (2R,3S)-BOC-E (2R,3S)-3-(N-BOC-Amino)-1,2-epoxy-4-phenylbutane t-Butyl{(1s)-1-[(2R-oxiran-2-yl]-2-phenylethyl}carbamate (R-OPC) 2'-deoxy-2',2'-difluoro-,3',5'-dibenzoate (T9)" (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane (Atazanavir Impurity) 98760-08-8 78760-08-8 98760-08-5 Heterocycles chiral Chiral Amino Epoxides Aromatics Compounds Aromatics Chiral Reagents