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Ethyl diethoxyphosphinylformate

Ethyl diethoxyphosphinylformate Structure
CAS No.
1474-78-8
Chemical Name:
Ethyl diethoxyphosphinylformate
Synonyms
Foscarnet EP Impurity D;Foscarnet impurity D CRS;TRIETHYL PHOSPHONOFORMATE;Triethyl carboxyphosphonate;Triethyl phosphonomethanoate;Foscarnet Related CoMpound D;Diethyl carbethoxyphosphonate;TRIETHYL PHOSPHONOFORMATE 98%;ethyl diethyl-phosphonoformate;Ethyl diethoxyphospinylformate
CBNumber:
CB6423762
Molecular Formula:
C7H15O5P
Molecular Weight:
210.16
MOL File:
1474-78-8.mol
Modify Date:
2023/4/23 13:52:06

Ethyl diethoxyphosphinylformate Properties

Boiling point 135 °C12 mm Hg(lit.)
Density 1.11 g/mL at 25 °C(lit.)
refractive index n20/D 1.423(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility Chloroform (Slightly), Methanol (Slightly)
color Colorless to Almost colorless
Specific Gravity 1.11
BRN 1781949
Stability Moisture Sensitive
CAS DataBase Reference 1474-78-8(CAS DataBase Reference)
NIST Chemistry Reference Phosphinecarboxylic acid, diethoxy-, ethyl ester, oxide(1474-78-8)
EPA Substance Registry System Phosphinecarboxylic acid, diethoxy-, ethyl ester, oxide (1474-78-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P280g-P302+P352a-P321-P333+P313-P501a
Hazard Codes  Xi
Risk Statements  36/37/38-43
Safety Statements  24/25-36/37-26-37-24
WGK Germany  3
TSCA  Yes
HS Code  2931 39 90
NFPA 704
1
1 0

Ethyl diethoxyphosphinylformate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR2870 Foscarnet Related Compound D pharmaceutical secondary standard, certified reference material 1474-78-8 0.5ML ₹56787.95 2022-06-14 Buy
TCI Chemicals (India) E0400 Ethyl Diethoxyphosphinylformate min. 98.0 % 1474-78-8 25G ₹2900 2022-05-26 Buy
Product number Packaging Price Buy
PHR2870 0.5ML ₹56787.95 Buy
E0400 25G ₹2900 Buy

Ethyl diethoxyphosphinylformate Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

Diethyl (Ethoxycarbonyl)phosphonate is an impurity in the synthesis of Foscarnet (F727400), an inhibitor of viral DNA polymerase and reverse transcriptase. Foscarnet is used as an antiviral.

General Description

for synthesis

Purification Methods

Dissolve it in Et2O, shake this with H2O (to remove any trace of NaCl impurity), dry (Na2SO4), evaporate and distil it using an efficient fractionating column. [Nylén Chem Ber 57 1035 1924, Reetz et al. J Am Chem Soc 77 3813 1955, Monson Advanced Organic Synthesis Academic Press p 89 1972, Beilstein 3 II 103.]

Ethyl diethoxyphosphinylformate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 154)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Grr Fine Chem/Grr Exports 91-79-40031771 Gujarat, India 405 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10259 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Diethyl carbethoxyphosphonate Diethyl ethoxycarbonylphosphonate Ethyl diethoxyphosphinecarboxylate oxide Formic acid, phosphono-, triethyl ester phosphinecarboxylicacid,diethoxy-,ethylester,oxide Triethyl carboxyphosphonate Triethyl phosphonomethanoate (ETHOXYCARBONYL)PHOSPHONIC ACID DIETHYL ESTER ETHYL DIETHOXYPHOSPHINYLFORMATE DIETHOXYPHOSPHINYLFORMIC ACID ETHYL ESTER TRIETHYL PHOSPHONOFORMATE TRIETHYL PHOSPHONOFORMATE 98% PhosphonoformicacidTriethylester Ethyl diethoxyphosphinylformate,98% TRIETHYL PHOSPHONOFORMATE (ETHYL DIETHOXYPHOSPHINILFORMATE) ethyl diethyl-phosphonoformate ETHYL DIETHOXYPHOSPHINYLFORMATE (TRIETHYL PHOSPHONOFORMATE) Foscarnet Related Compound D (0.27 mL) (O,O-diethyl ethoxycarbonylphosphonate) Diethoxyphosphinylformic Acid Ethyl Ester (Ethoxycarbonyl)phosphonic Acid Diethyl Ester Triethyl Phosphonoformate Foscarnet Related CoMpound D Ethyl diethoxyphospinylformate Foscarnet Related Compound D (O,O-diethyl ethoxycarbonylphosphonate) (1283324) Foscarnet EP Impurity D Phosphinecarboxylic acid, 1,1-diethoxy-, ethyl ester, 1-oxide Foscarnet impurity D CRS Foscarnet Sodium Impurity 4(Foscarnet Sodium EP Impurity D) Foscarnet Sodium EP Impurity D Foscarnet USP Related Compound D Foscarnet Sodium Hexahydrate EP Impurity D Foscarnet Sodium EP Impurity D (Foscarnet USP Related Compound D) 1474-78-8 C2H5O2POCOOC2H5 C7H15O5P Building Blocks Phosphorus Compounds Phosphonates/Phosphinates Organic Building Blocks Organic Building Blocks Phosphonates/Phosphinates Phosphorus Compounds