U-46619
- CAS No.
- 56985-40-1
- Chemical Name:
- U-46619
- Synonyms
- U-46619;U 46619,U46619;9,11-Methanoxy-PGH2;11-Methanoepoxy PGH2;9,11-Methanoepoxy PGH2;U46619, U-46619, U 46619;11α,9α-Epoxymethanoprostaglandin H2;U-46619 - CAS 56985-40-1 - Calbiochem;9,11-DIDEOXY-11ALPHA,9ALPHA-EPOXYMETHANO;4-alpha,5-beta(z),6-alpha(1e,3s*)))-r-(1-alph
- CBNumber:
- CB6437516
- Molecular Formula:
- C21H34O4
- Molecular Weight:
- 350.49
- MOL File:
- 56985-40-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:14
| Boiling point | 519.7±30.0 °C(Predicted) |
|---|---|
| Density | 1.092±0.06 g/cm3(Predicted) |
| Flash point | -10 °C |
| storage temp. | -20°C |
| solubility | ≥100 mg/mL in DMSO, ≥100 mg/mL in Ethanol, ≥100 mg/mL in DMF, ≥2 mg/mL in PBS pH 7.2 |
| pka | 4.76±0.10(Predicted) |
| form | solution |
| color | Colorless to light yellow |
| BRN | 4267334 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319-H336 | |||||||||
| Precautionary statements | P210-P305+P351+P338 | |||||||||
| Hazard Codes | F,Xi | |||||||||
| Risk Statements | 11-36-66-67 | |||||||||
| Safety Statements | 16-26 | |||||||||
| RIDADR | UN 1231 3/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | MJ9681090 | |||||||||
| F | 8-10-23 | |||||||||
| Toxicity | LD50 intravenous in mouse: 66ug/kg | |||||||||
| NFPA 704 |
|
U-46619 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D8174 | 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10?mg/mL in methyl acetate | 56985-40-1 | 1MG | ₹34261.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D8174 | 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10?mg/mL in methyl acetate | 56985-40-1 | 5MG | ₹107286.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D8174 | 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10?mg/mL in methyl acetate | 56985-40-1 | 10MG | ₹189718.95 | 2022-06-14 | Buy |
U-46619 Chemical Properties,Uses,Production
Uses
U 46619 is a PGH2 analog that may be used as a thromboxane A2 (TP) receptor agonist affecting mitogenic growth of vascular smooth muscle in humans.
Biological Activity
PGH 2 (TXA 2 ) analog that is a potent and stable thromboxane A 2 (TP) receptor agonist (EC 50 = 0.035 μ M). Potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations. Activates ERK-1 and ERK-2 in HEK-293 cells expressing TP α and TP β receptors.
Biochem/physiol Actions
Thromboxane receptor agonist.
U-46619 Preparation Products And Raw materials
Raw materials
Preparation Products
U-46619 Suppliers
Global( 63)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | China | 25014 | 65 | Inquiry |
| Shanghai klamar Reagent Co., LTD | 4001650900 13817534909 | China | 10709 | 58 | Inquiry |
| DC Chemicals | 021-58447131 13564518121 | China | 9412 | 58 | Inquiry |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | China | 3451 | 58 | Inquiry |
56985-40-1(U-46619)Related Search:
9,11-DIDEOXY-11ALPHA,9ALPHA-EPOXYMETHANO
9,11-DIDEOXY-11A,9A-EPOXYMETHANO-*PROSTA GLANDIN F2A
9,11-dideoxy-11α,9α-epoxymethanoprostaglandin f2α
9,11-dideoxy-11alpha,9alpha-epoxymethanoprostaglandin F2a
(5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2 -oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid
(5Z)-7-[(1R,4S)-6β-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]heptan-5α-yl]-5-heptenoic acid
(Z)-7-[(1R,4S)-6β-[(E,S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5α-yl]-5-heptenoic acid
11α,9α-Epoxymethanoprostaglandin H2
9,11-Methanoepoxy PGH2
9,11-Methanoxy-PGH2
9,11-Dideoxy-9α,11α-methanoepoxyprostaglandin F2α Solution
4-alpha,5-beta(z),6-alpha(1e,3s*)))-r-(1-alph
7-(6-(3-hydroxy-1-octenyl)-2-oxabicyclo(2.2.1)hept-5-yl)-5-heptenoicaci(1
9a,11a-methanoepoxy-15-hydroxyprosta-5,13-dienoicacid
U-46619
9,11-dideoxy-11A,9A-epoxymethano-*prostaglandin F
9,11-dideoxy-11alpha,9alpha-epoxymethano prostaglandin F2A S
9,11-DIDEOXY-9ALPHA, 11ALPHA-METHANOEPOXY-PROSTA-5Z,13E-DIEN-1-OIC ACID
9,11-DIDEOXY-9ALPHA, 11ALPHA-METHANOEPOXY-PROSTA-5Z,13E-DIEN-OIC ACID
9,11-DIDEOXY-9ALPHA,11ALPHA-METHANOEPOXYPROSTAGLANDIN F2ALPHA
9,11-DIDEOXY-11ALPHA,9ALPHA-EPOXY-METHANOPROSTAGLANDIN F2ALPHA
9,11-DIDEOXY-9ALPHA,11ALPHA-METHANOEPOXY PGF2ALPHA
9,11-DIDEOXY-11Α,9Α-EPOXYMETHANOPROSTAGLANDIN F2Α,SOLUTION
U-46619 - CAS 56985-40-1 - Calbiochem
5-Heptenoic acid, 7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl]-, (5Z)-
11-Methanoepoxy PGH2
U46619, U-46619, U 46619
U 46619,U46619
56985-40-1
Biochemicals and Reagents
BioChemical
Prostaglandins
Lipids
Fatty Acids
Prostanoid receptor and related