L-CYSTATHIONINE

L-CYSTATHIONINE Structure
CAS No.
56-88-2
Chemical Name:
L-CYSTATHIONINE
Synonyms
L-CYSTATHIONINE;L(+)CYSTATHIONINE;CYSTATHIONINE, L-;L-Cystathionine (P);L-Cystathionine Standard;L-CYSTATHIONINE, >= 98% (TLC);CYSTATHIONINE, L-(DS)(REQUEST QUOTE);(2R,7S)-2,7-Diamino-4-thiaoctanedioic acid;[R]-S-[2-AMINO-2-CARBOXYETHYL]-L-HOMOCYSTEINE;S-[(R)-2-Amino-2-carboxyethyl]-L-homocysteine
CBNumber:
CB6446239
Molecular Formula:
C7H14N2O4S
Molecular Weight:
222.26
MOL File:
56-88-2.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:16

L-CYSTATHIONINE Properties

Melting point 312
alpha D20 +23.7° (1N HCl)
Density 1.430±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. -20°C
solubility Aqueous Acid (Slightly)
form Solid
Boiling point 481.0±45.0 °C(Predicted)
pka 2.08±0.10(Predicted)
color White to Off-White
Merck 13,2807
BRN 2505200

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
WGK Germany  3
10-21
HS Code  29309090
NFPA 704
0
2 0

L-CYSTATHIONINE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C7505 L-Cystathionine ≥98% (TLC) 56-88-2 10MG ₹9710.03 2022-06-14 Buy
Sigma-Aldrich(India) C7505 L-Cystathionine ≥98% (TLC) 56-88-2 50MG ₹22916.53 2022-06-14 Buy
Sigma-Aldrich(India) C7505 L-Cystathionine ≥98% (TLC) 56-88-2 250MG ₹92239.83 2022-06-14 Buy
Product number Packaging Price Buy
C7505 10MG ₹9710.03 Buy
C7505 50MG ₹22916.53 Buy
C7505 250MG ₹92239.83 Buy

L-CYSTATHIONINE Chemical Properties,Uses,Production

Description

L-(+)-Cystathionine is a dipeptide formed by serine and homocysteine. Transsulfuration of methionine yields homocysteine, which combines with serine to form this precursor of cysteine. L-(+)-Cystathionine is largely expressed in the mammalian brain and deficiency can indicate the presence of metabolic disorders such as cystathioninuria.

Chemical Properties

White Crystalline Solid

Uses

L-Cystathionine has been used in ultra-performance liquid chromatography for the validation of cystathionine and the correlation of its abundance with vertebrate metamorphosis. It has also been used as an inhibitor of sinusoidal GSH (glutathione) carrier to signify that thiol redox state imbalance is associated with the modulation of autophagy in carcinoma cells.

Purification Methods

S,S-Cystathionine is purified by converting it to the HCl salt in 20% HCl and carefully basifying with aqueous NH3 until separation is complete. Filter it off and dry it in a vacuum. It forms prisms from H2O. The dibenzoyl derivative has m 229o (from EtOH). [IR: Greenstein & Winitz Chemistry of the Amino Acids (J Wiley) Vol 3 p2690 1961 and Tallan et al. J Biol Chem 230 707 1958, Synthesis: du Vigneaud et al. J Biol Chem 143 59 1942, Anslow et al. J Biol Chem 166 39 1946.] [Prepn: Weiss & Stekol J Am Chem Soc 73 2497 1951; see also du Vigneaud et al. J Biol Chem 143 60 1942, Biological synthesis: Greenberg Methods Enzymol 5 943 1962, Beilstein 4 IV 3197.]

L-CYSTATHIONINE Preparation Products And Raw materials

Raw materials

Preparation Products

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CYSTATHIONINE, L- L(+)CYSTATHIONINE L-CYSTATHIONINE L-CYSTATHIONINE, >= 98% (TLC) [R]-S-[2-AMINO-2-CARBOXYETHYL]-L-HOMOCYSTEINE (2S)-2-amino-4-[(2R)-2-amino-3-hydroxy-3-oxopropyl]sulfanylbutanoic acid L-Cystathionine,(R)-S-(2-Amino-2-carboxyethyl)-L-homocysteine (2S)-2-Amino-4-{[(2R)-2-amino-2-carboxyethyl]thio}butanoic acid [R-(R*,S*)]-2-AMino-4-[(2-aMino-2-carboxyethyl)thio]butanoic Acid S-[(2R)-2-AMino-2-carboxyethyl]-L-hoMocysteine CYSTATHIONINE, L-(DS)(REQUEST QUOTE) (2R,7S)-2,7-Diamino-4-thiaoctanedioic acid S-[(R)-2-Amino-2-carboxyethyl]-L-homocysteine L-Homocysteine, S-[(2R)-2-amino-2-carboxyethyl]- L-Cystathionine Standard L-Cystathionine (P) 56-88-2 Amino Acid Library BioChemical Metabolic Libraries Metabolomics Cysteine Derivatives Peptide Synthesis Specialty Synthesis Unnatural Amino Acid Derivatives Amino Acids 13C, 2H, 15N Amino Acids & Derivatives Intermediates Sulfur & Selenium Compounds