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6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Structure
CAS No.
153559-76-3
Chemical Name:
6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID
Synonyms
LG 268;CD 3127;lg100268;ALRT 268;LGD 1268;AGN 192620;LGD 100268;hthalenyl)cyclopropyl)-;3-pyridinecarboxylicacid,6-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-nap;6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]nicotinic Acid
CBNumber:
CB6458625
Molecular Formula:
C24H29NO2
Molecular Weight:
363.49
MOL File:
153559-76-3.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Properties

Melting point 275-277°C
Boiling point 487.0±33.0 °C(Predicted)
Density 1.115±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: ≥5mg/mL (warmed)
pka 2.35±0.10(Predicted)
form powder
color white to beige

SAFETY

Risk and Safety Statements

WGK Germany  3

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0279 LG100268 ≥98% (HPLC) 153559-76-3 5MG ₹14386.43 2022-06-14 Buy
Sigma-Aldrich(India) SML0279 LG100268 ≥98% (HPLC) 153559-76-3 25MG ₹57632.3 2022-06-14 Buy
Product number Packaging Price Buy
SML0279 5MG ₹14386.43 Buy
SML0279 25MG ₹57632.3 Buy

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM).

Biochem/physiol Actions

LG100268 (LG268) is a potent and selective rexinoid and retinoid-X receptor (RXR) agonist. LG100268 binds to the α, β and γ RXR receptors with an IC50 = 3-4 nM and has no activity at the RAR retinoic acid receptors.

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Suppliers

Global( 51)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Sigma-Aldrich 021-61415566 800-8193336 China 51471 80 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 China 12308 58 Inquiry
MedChemExpress 021-58955995 United States 6398 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; China 29778 58 Inquiry
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 China 8888 55 Inquiry
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 China 11289 58 Inquiry
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 China 49323 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
Sigma-Aldrich 80
Beijing Jin Ming Biotechnology Co., Ltd. 58
MedChemExpress 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Nanjing Norris-Pharm Technology Co., Ltd 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58

153559-76-3(6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID)Related Search:

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID 6-TERT-BUTYL-3-FORMYLPYRIDINE 1,4,6,7-TETRAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE 1,2,4-TRI-ISO-PROPYLBENZENE METHYL 6-(1-(1,2,3,4-TETRAHYDRO-1,1,4,4,6-PENTAMETHYLNAPHTHALEN-7-YL)CYCLOPROPYL)PYRIDINE-3-CARBOXYLATE
2-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]pyridine-5-carboxylic acid 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID 6-[1-(3,5,5,8,8-PentaMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid 3-Pyridinecarboxylicacid,6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentaMethyl-2-naphthalenyl)cyclopropyl]- 3-pyridinecarboxylicacid,6-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-nap hthalenyl)cyclopropyl)- lg100268 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID (FOR R&D ONLY) 6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]- 3-Pyridinecarboxylic Acid AGN 192620 ALRT 268 CD 3127 LG 268 LGD 100268 LGD 1268 6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]nicotinic Acid 153559-76-3 Intermediates & Fine Chemicals Pharmaceuticals Retinoids