Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Dolutegravir 2-Desfluoro Impurity

Dolutegravir 2-Desfluoro Impurity

Dolutegravir 2-Desfluoro Impurity Structure
CAS No.
1863916-88-4
Chemical Name:
Dolutegravir 2-Desfluoro Impurity
Synonyms
4-Fluoro Dolutegravir;Dolutegravir Impurity G;Dolutegravir Impurity 50;Dolutegravir Impurity 47;Dolutegravir 4-Fluoro Impurity;Dolutegravir 2-Desfluoro Impurity;(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity;Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
CBNumber:
CB64796145
Molecular Formula:
C20H20FN3O5
Molecular Weight:
401.39
MOL File:
1863916-88-4.mol
Modify Date:
2023/7/12 17:02:14
Request For Quotation

Dolutegravir 2-Desfluoro Impurity Properties

Boiling point 675.7±55.0 °C(Predicted)
Density 1.49±0.1 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka 4.50±1.00(Predicted)
color Off-White to Light Brown

Dolutegravir 2-Desfluoro Impurity Chemical Properties,Uses,Production

Uses

Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 2-Desfluoro Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

Dolutegravir 2-Desfluoro Impurity Suppliers

Global( 32)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
GLP Pharma Standards +91 9866074638 Hyderabad, India 1644 58 Inquiry
Varanous Labs Pvt Ltd +91-7036248882 +91-7036248882 Hyderabad, India 1541 58 Inquiry
CHEMAZON LABORATORIES +91 9848551964 Hyderabad, India 1320 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Chemicea Pharmaceuticals Pvt Ltd +91-9881765045/+91-8796656135 Pune, India 825 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12382 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Supplier Advantage
GLP Pharma Standards 58
Varanous Labs Pvt Ltd 58
CHEMAZON LABORATORIES 58
Pharma Affiliates 58
Chemicea Pharmaceuticals Pvt Ltd 58
CLEARSYNTH LABS LTD. 58
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
sgtlifesciences pvt ltd 58
China National Standard Pharmaceutical Corporation Limited 58

1863916-88-4(Dolutegravir 2-Desfluoro Impurity)Related Search:

Dolutegravir 4-Desfluoro Impurity IMpurity of Dolutegravir GSK1349572 Dolutegravir Impurity 3 Dolutegravir sodium
Dolutegravir Impurity 6 O-Methyl Dolutegravir
chevron_left

1of2

chevron_right
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Dolutegravir Impurity G Dolutegravir 2-Desfluoro Impurity 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)- (4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Dolutegravir Impurity 47 Dolutegravir Impurity 50 4-Fluoro Dolutegravir Dolutegravir 4-Fluoro Impurity 1863916-88-4