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1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE

1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE Structure
CAS No.
162054-19-5
Chemical Name:
1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE
Synonyms
SC-58125;SC-58125, 10 mM in DMSO;1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE;5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)pyrazole;5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3-trifluoromethyl-1H-pyrazole;5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole;1H-Pyrazole, 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-;Cyclooxygenase,cancer,SC58125,COX,Inhibitor,SC-58125,inflammatory,antitumor,COX-2,edema,inhibit
CBNumber:
CB6486473
Molecular Formula:
C17H12F4N2O2S
Molecular Weight:
384.35
MOL File:
162054-19-5.mol
MSDS File:
SDS
Modify Date:
2025/4/17 18:22:24
Request For Quotation

1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE Properties

storage temp. Store at +4°C
solubility DMSO: ≥20mg/mL
form powder
color white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  T
Risk Statements  25
Safety Statements  45-24/25-22
WGK Germany  3
NFPA 704
0
2 0

1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PZ0139 SC-58125 ≥98% (HPLC) 162054-19-5 5MG ₹13184.85 2022-06-14 Buy
Sigma-Aldrich(India) PZ0139 SC-58125 ≥98% (HPLC) 162054-19-5 25MG ₹51180.6 2022-06-14 Buy
Product number Packaging Price Buy
PZ0139 5MG ₹13184.85 Buy
PZ0139 25MG ₹51180.6 Buy

1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor with anti-inflammatory properties. SC-58125 blocks edema and hyperalgesia without causing gastric mucosal damage. SC-58125 also displays anti tumor activity.

Definition

ChEBI: A member of the class of pyrazoles that is 1H-pyrazole substituted by a 4-fluorophenyl group at position 5, a 4-(methylsulfonyl)phenyl group at position 1 and a trifluoromethyl group at position 3. A selective cyclooxygenase 2 inhibitor it exhibits anticancer property.

Biological Activity

Selective cyclooxygenase 2 (COX-2) inhibitor (IC 50 values are 0.04 and >100 μ M for COX-2 and COX-1 respectively). Anti-inflammatory; blocks edema and hyperalgesia in vivo following an inflammatory insult, without causing gastric mucosal damage. Also displays antitumor activity.

1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE Suppliers

Global( 64)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32202 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131957 58 Inquiry
Boao Pike 010-57798038 15652371397 CHINA 6629 58 Inquiry
Resenbio 029-86354885 China 1774 50 Inquiry
Shanghai Yuda Industrial Co., Ltd. 021-64133189 13788995069 CHINA 6105 58 Inquiry
Shanghai Hao Biological Technology Co., Ltd. 021-58116080 18019263206 CHINA 6906 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6650 58 Inquiry
Shanghai Jingke Chemical Technology Co., Ltd. 021-54997581 13524423207 CHINA 6972 58 Inquiry
Beijing Baiao Innovation Technology Co., Ltd. 010-5718533 13366620421 CHINA 6002 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
TargetMol Chemicals Inc. 58
Amadis Chemical Company Limited 58
Boao Pike 58
Resenbio 50
Shanghai Yuda Industrial Co., Ltd. 58
Shanghai Hao Biological Technology Co., Ltd. 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Shanghai Jingke Chemical Technology Co., Ltd. 58
Beijing Baiao Innovation Technology Co., Ltd. 58

1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE Spectrum

1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE(162054-19-5)1HNMR

162054-19-5(1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE)Related Search:

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4'-Hydroxyacetophenone 3-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE 3-(4-Fluorophenyl)-1H-pyrazole 1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE 5-(TRIFLUOROMETHYL)-3-(4-FLUOROPHENYL)-1H-PYRAZOLE
1,5-DIPHENYL-3-METHYL-1H-PYRAZOLE 3-DIFLUOROMETHYL-5-PHENYLPYRAZOLE 1,5-DIPHENYL-3-TRIFLUOROMETHYL-1H-PYRAZOLE 3-TRIFLUOROMETHYL-5-METHYL-1-(PHENYL)PYRAZOLE 5-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOLE
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SC-58125 1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE 5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)pyrazole 5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole 5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3-trifluoromethyl-1H-pyrazole 1H-Pyrazole, 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)- Cyclooxygenase,cancer,SC58125,COX,Inhibitor,SC-58125,inflammatory,antitumor,COX-2,edema,inhibit SC-58125, 10 mM in DMSO 162054-19-5 C17H12F4N2O2S