ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Nitro compounds >L-Glutamic acid γ-(4-nitroanilide)
L-Glutamic acid γ-(4-nitroanilide)
- CAS No.
- 7300-59-6
- Chemical Name:
- L-Glutamic acid γ-(4-nitroanilide)
- Synonyms
- UTAMYL;GLU-PNA;Glu-4NA;ST5307107;110893-27-1;G1135_SIGMA;-p-NITROANIL;H-GLU(PNA)-OH;GPNA/H-Glu-PNA;EINECS 230-748-5
- CBNumber:
- CB6496764
- Molecular Formula:
- C11H13N3O5
- Molecular Weight:
- 267.24
- MOL File:
- 7300-59-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/8 17:36:42
| Melting point | 185-188°C |
|---|---|
| alpha | [α]D20 +36～+39°(c=2,dil.HCl) |
| Boiling point | 590.6±50.0 °C(Predicted) |
| Density | 1.463 |
| refractive index | 32 ° (C=2, 0.5mol/L HCl) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly) |
| form | Solid |
| pka | 2.21±0.10(Predicted) |
| color | White to Pale Yellow |
| BRN | 2818758 |
| InChI | InChI=1S/C11H13N3O5/c12-10(15)6-5-9(11(16)17)13-7-1-3-8(4-2-7)14(18)19/h1-4,9,13H,5-6H2,(H2,12,15)(H,16,17)/t9-/m0/s1 |
| InChIKey | IMTMBDXEKMXETQ-VIFPVBQESA-N |
| SMILES | C(O)(=O)[C@H](CCC(N)=O)NC1=CC=C([N+]([O-])=O)C=C1 |
| CAS DataBase Reference | 7300-59-6(CAS DataBase Reference) |
| EPA Substance Registry System | L-Glutamine, N-(4-nitrophenyl)- (7300-59-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29242990 | |||||||||
| NFPA 704 |
|
L-Glutamic acid γ-(4-nitroanilide) price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G1135 | L-Glutamic acid γ-(4-nitroanilide) γ-glutamyl transpeptidase substrate | 7300-59-6 | 1G | ₹4557.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G1135 | L-Glutamic acid γ-(4-nitroanilide) γ-glutamyl transpeptidase substrate | 7300-59-6 | 5G | ₹17785.48 | 2022-06-14 | Buy |
| TCI Chemicals (India) | G0065 | L-γ-Glutamyl-p-nitroanilide Monohydrate | 7300-59-6 | 1G | ₹4100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | G0065 | L-γ-Glutamyl-p-nitroanilide Monohydrate | 7300-59-6 | 5G | ₹18000 | 2022-05-26 | Buy |
L-Glutamic acid γ-(4-nitroanilide) Chemical Properties,Uses,Production
Description
L-Glutamic acid γ-(4-nitroanilide) is a substrate for γ-glutamyltransferase (GGT). It is an important enzyme that is widely used in biocatalysis and clinical diagnostics.
Chemical Properties
cream coloured to light yellow powder
Uses
Substrate for gamma-glutamyl transpeptidase
Preparation
To a microwave vial containing a solution of Boc-L-glutamic acid tert-butyl ester (0.165 mmol, 1.0 equiv) and HATU (0.165 mmol, 1.0 equiv) in DMF (1.65 mL) was added the amine followed by DIPEA (57.5 μL, 2.0 equiv). The vial was sealed and heated under microwave irradiation for 30 min at 120 °C. Upon completion, the reaction was partitioned between water and CH2Cl2, extracted 3× with CH2Cl2, dried over anhydrous Na2SO4, and concentrated under vacuum. Compounds were purified via reverse phase chromatography (5-95% acetonitrile/water) to afford the N-Boc-glutamylanilide-tert-butyl esters. The compounds were transferred to vials followed by the addition of 2.0 mL of 4.0 M HCl in dioxane. The reaction stirred at 40 °C for 4 h. The reactions were concentrated under vacuum to afford L-Glutamic acid γ-(4-nitroanilide).
Solubility in water
Soluble in water, formic acid (50 mg/ml), and 0.5mol/l hydrochloric acid. Chloroform: Slightly soluble. DMF: Slightly soluble. DMSO: Slightly soluble. Ethanol: Slightly soluble. Methanol: Slightly soluble. PBS (pH 7.2): Slightly soluble
L-Glutamic acid γ-(4-nitroanilide) Preparation Products And Raw materials
L-Glutamic acid γ-(4-nitroanilide) Suppliers
Global( 129)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
| SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34571 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23555 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
7300-59-6(L-Glutamic acid γ-(4-nitroanilide))Related Search:
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GAMMA-L-GLUTAMYL-P-NITROANILIDE HYDRATE,GAMMA-L-GLUTAMYL P-NITROANILIDE, MONOHYDRATE
DL-Glutamine
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L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT
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L-Glutamic acid γ-(4-nitroanilide)
N-(4-Aminophenyl)propanamide
4-Nitroaniline
H-GLU-PNA
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-Glutamyl-p-nitroanilide Monohydrate
L-&gamma
L-gamma-Glutamyl-p-nitroanilide
gamma-glutamine-4-nitroanilide
L-GLUTAMIC ACID 5-(4-NITROANILIDE)
L-GAMMA-GLUTAMYL-P-NITROANILIDE
GLUTAMIC ACID(PNA)-OH
H-GLU(PNA)-OH
GAMMA-L-GLU-P-NITROANILIDE
GAMMA-L-GLUTAMYL-4-NITROANILIDE
GAMMA-L-GLUTAMYL-P-NITROANILIDE
GLU-PNA
L-Glutamic acid 5-(4-nitroanilide) monohydrate
L-γ-Glutamyl-p-nitroanilide monohydrate≥ 98% (HPLC)
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE)*F REE BASE
gamma-L-Glutamyl-4-nitroanilide, 98.5%
L-Glutamine, N-(4-nitrophenyl)-
l-glutamic acid γ-(4-nitroanilide)
N-(4-nitrophenyl)-L-glutamine
g-L-Glutamyl-4-nitroanilide
^y-L-Glutamyl-4-nitroanilide, 98+%
L-gamma-Glutamyl-p-nitroanilide monohydrate,98%
gamma-L-Glutamyl-4-nitroanilide, 98+%
GaMMa - L - glutaMine paranitroaniline a hydrate
L-gaMMa- glutaMyl - on - nitroaniline
L-Glutamyl-4-nitroanilide
N-(4-Nitrophenyl)-L-glutamine
(2S)-2-amino-5-[(4-nitrophenyl)amino]-5-oxopentanoic acid
(2S)-2-amino-5-[(4-nitrophenyl)amino]-5-oxo-pentanoic acid
(2S)-2-amino-5-keto-5-[(4-nitrophenyl)amino]valeric acid
(2S)-2-azaniumyl-5-[(4-nitrophenyl)amino]-5-oxopentanoate
L-γ-GlutaMyl-p-nitroanilide Monohydrate
(S)-2-AMino-5-((4-nitrophenyl)aMino)-5-oxopentanoic acid
L-GlutaMy-4-nitroanilide MoMhydrate
110893-27-1
EINECS 230-748-5
G1135_SIGMA
L-2-Amino-4'-nitroglutaranilic acid
L-Glutamic acid gamma-(4-nitroanilide)
N~5~-(4-nitrophenyl)glutamine
ST5307107
GPNA/H-Glu-PNA
nomega-(4-nitrophenyl)-l-glutamine
L-Y-GLUTAMIC ACID-P-NITROANILIDE MONOHYDRATE
γ-L-Glutamyl-4-nitroanilide, 98+%
gamma-glutamyl-p-nitroanilide
L-γ-Glutamyl-p-nitroanilide, L-Glutamic acid 5-(4-nitroanilide)
Glu-4NA
L-Gulutamic acid γ-p-nitroanilide
γ-Glutamyl-p-nitroanilide
GPNA, L-γ-Glutamyl-p-nitroanilide
L-Gulutamic Acid
L-γ-Glutamyl-p-nitroanilideMonohydrate>
-p-NITROANIL
UTAMYL
γ-L-GLUTAMYL-p-NITROANILIDE
Nω-(4-Nitrophenyl)-L-glutamine Monohydrate
γ-L-Glutamyl-Pnitroanilide monohydrate
L-Glutamic acid gamma-(4-nitroanilide) gamma-glutamyl transpeptidase substrate