(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Structure
CAS No.
148700-85-0
Chemical Name:
(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
Synonyms
L 733060;L-733,060 hydrochlor;L-733,060 HYDROCHLORIDE;3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine;Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-;(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
CBNumber:
CB6676120
Molecular Formula:
C20H19F6NO
Molecular Weight:
403.36
MOL File:
148700-85-0.mol
Modify Date:
2023/5/4 17:34:33

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Properties

storage temp. 2-8°C
solubility DMSO: >10 mg/mL
form solid
color white

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Biological Activity

A potent antagonist of human tachykinin NK 1 receptors (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze; orally bioavailable and brain penetrant.

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Suppliers

Global( 18)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
BIOTREND Chemicals AG +41 44 805 76 76 Germany 1250 62 Inquiry
Beijing Seajet Scientific Inc 010-88597838,9569,8795 China 378 70 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
MOLEKULA Ltd. +44 (0) 1747 831066 United Kingdom 6152 66 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Shanghai Chaoyan Biotechnology Co., Ltd. 021-50840550 CHINA 6217 58 Inquiry
Shanghai Weiwei Biological Technology Co., Ltd. 021-55669583 18616258598 CHINA 4398 58 Inquiry
L-733,060 HYDROCHLORIDE (2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE 3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine L 733060 Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)- L-733,060 hydrochlor 148700-85-0 Tachykinin receptor