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Tetrahydrouridine

Tetrahydrouridine Structure
CAS No.
18771-50-1
Chemical Name:
Tetrahydrouridine
Synonyms
nsc-112907;nsc-112907-d;DFMA | RMI 71897;TETRAHYDROURIDINE;3,4,5,6-tetrahydrouridine;Tetrahydrouridine dihydrate;Uridine, 3,4,5,6-tetrahydro-;3,4,5,6-Tetrahydrouridine (>3,4,5,6-Tetrahydrouridine (>80%);Tetrahydrouridine (aqueous solution)
CBNumber:
CB6748654
Molecular Formula:
C9H16N2O6
Molecular Weight:
248.23
MOL File:
18771-50-1.mol
Modify Date:
2023/5/18 11:30:59
Request For Quotation

Tetrahydrouridine Properties

Melting point >195°C (dec.)
Boiling point 668.6±55.0 °C(Predicted)
Density 1.622±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Methanol (Slightly), Water (Slightly)
form Solid
pka 12.50±0.40(Predicted)
color White to Off-White
Stability Light Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Tetrahydrouridine price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 584223 InSolution Tetrahydrouridine - CAS 18771-50-1 - Calbiochem Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase. 18771-50-1 25MG ₹39950 2022-06-14 Buy
Product number Packaging Price Buy
584223 25MG ₹39950 Buy

Tetrahydrouridine Chemical Properties,Uses,Production

Description

Tetrahydrouridine is a competitive, reversible inhibitor of cytidine deaminase (Ki values = 54 and 240 nM for human and E. coli enzymes, respectively). Its use, alone or in combination with the DNA methyltransferase inhibitor 5-fluoro-2’-deoxycytidine, is being evaluated in animal models and clinical trials for diseases, including cancer and mitochondrial DNA depletion syndrome.

Uses

3,4,5,6-Tetrahydrouridine, is a derivative of Uridine (U829910). Tetrahydrouridine (THU), is a potent inhibitor of cytidine. It inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels deaminase (CDA), and thus can be used as a potential and promising treatment for tumors with highly expressed CDA.

Tetrahydrouridine Preparation Products And Raw materials

Raw materials

Preparation Products

Tetrahydrouridine Suppliers

Global( 90)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 13164 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
NewCan Biotech Limited +86-0571-86912261 +8613735419629 China 9980 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
Shandong Zhishang New Material Co., Ltd. +8617653113209 China 3050 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
Pharma Affiliates 58
CONIER CHEM AND PHARMA LIMITED 58
Zhengzhou Alfa Chemical Co.,Ltd 58
TargetMol Chemicals Inc. 58
NewCan Biotech Limited 58
Labnetwork lnc. 58
Shandong Zhishang New Material Co., Ltd. 58

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Propyleneurea Tetrahydrouridine 5,6-Dihydrouridine
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3,4,5,6-Tetrahydrouridine (>80% by HPLC) (4S)-3,4,5,6-Tetrahydro-4β-hydroxy-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-one 3,4,5,6-tetrahydrouridine nsc-112907 nsc-112907-d tetrahydro-4-hydroxy-1-beta-d-ribofuranosyl-2(1h)-pyrimidinon TETRAHYDROURIDINE Uridine, 3,4,5,6-tetrahydro- 3,4,5,6-Tetrahydrouridine (> Tetrahydrouridine dihydrate 3,4,5,6-Tetrahydrouridine (>80%) Uridine Impurity 27（Tetrahydrouridine） 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one DFMA | RMI 71897 Tetrahydro uridineQ: What is Tetrahydro uridine Q: What is the CAS Number of Tetrahydro uridine Q: What is the storage condition of Tetrahydro uridine Q: What are the applications of Tetrahydro uridine Tetrahydrouridine (aqueous solution) 18771-50-1