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thonzylamine hydrochloride

thonzylamine hydrochloride Structure
CAS No.
63-56-9
Chemical Name:
thonzylamine hydrochloride
Synonyms
NH 188;Anahist;Resistab;Novohetramin;Thonzylamine HCl;Thonzylamine HCl 98%;Thonzilamine hydrochloride;Neohetramine hydrochloride;thonzylamine hydrochloride;thonzylamine hydrochloride ISO 9001:2015 REACH
CBNumber:
CB6875530
Molecular Formula:
C16H22N4O.ClH
Molecular Weight:
322.84
MOL File:
63-56-9.mol
MSDS File:
SDS
Modify Date:
2024/1/5 22:10:32

thonzylamine hydrochloride Properties

Melting point 173-176°
Boiling point bp2.2 185-187°
Density 1.2562 (rough estimate)
refractive index 1.5800 (estimate)
Stability Stable. Incompatible with strong oxidizing agents.
EPA Substance Registry System Thonzylamine hydrochloride (63-56-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H312
Precautionary statements  P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P310-P321-P330-P405-P501
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
Toxicity LD50 orally in guinea pigs: 493 mg (base)/kg (Reinhard, Seudi)

thonzylamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White, crystalline powder; faint odor. Very soluble in water; freely soluble in alcohol and chloroform; practically insoluble in ether and benzene; pH 5.0–6.0 (2% solution).

Uses

Medicine (antihistamine).

General Description

Thonzylamine hydrochloride,2-[[2-(dimethylamino)-ethyl](p-methoxybenzyl)amino]pyrimidine hydrochloride, is a white crystallinepowder soluble in water (1:1), in alcohol (1:6), and in chloroform(1:4). A 2% aqueous solution has a pH of 5.5. It is similar in activity to tripelennamine but is claimed to be lesstoxic. The usual dose is 50 mg taken up to 4 times daily. Itis available in certain combination products.

Air & Water Reactions

Water soluble.

Reactivity Profile

thonzylamine hydrochloride behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Health Hazard

SYMPTOMS: Symptoms of exposure to thonzylamine hydrochloride may include drowsiness, lethargy, fatigue, hypnosis, coma, vertigo, ataxia, tinnitus, blurred vision, tremors, anxiety, insomnia, excitement, hallucinations, delirium, convulsions, dry mouth, anorexia, nausea, vomiting, abdominal distress, constipation, diarrhea, central nervous system depression, gastrointestinal reactions, respiratory arrest and circulatory collapse.

Fire Hazard

Flash point data for thonzylamine hydrochloride are not available. thonzylamine hydrochloride is probably combustible.

thonzylamine hydrochloride Preparation Products And Raw materials

Global( 35)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ARCTIC EXPORTS INC +1-3026880818 +1-3026880818 Canada 68 58 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9337 55 Inquiry
SHANDONG ZHI SHANG CHEMICAL CO.LTD +86 18953170293 China 2931 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25196 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
Golden Pharma Co., Limited +undefined18958062155 China 5905 58 Inquiry
Shanghai Likang New Materials Co., Limited +86-16631818819 +86-17736933208 China 9311 58 Inquiry

thonzylamine hydrochloride Spectrum

Thonzilamine hydrochloride 1,2-Ethanediamine, N-(4-methoxyphenyl)methyl-N,N-dimethyl-N-2-pyrimidinyl-, monohydrochloride Anahist Neohetramine hydrochloride Resistab N-(4-Methoxybenzyl)-N-(2-(diMethylaMino)ethyl)pyriMidin-2-aMine thonzylamine hydrochloride NH 188 N-p-Methoxybenzyl-N',N'-dimethyl-N-2-pyrimidinylethylene diamine hydrochloride Thonzylamine HCl 98% Thonzylamine HCl N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine,hydrochloride thonzylamine hydrochloride ISO 9001:2015 REACH N1-(4-methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine hydrochloride Novohetramin 63-56-9 C16H22N4OHCl API